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Analysis of execution traces plays a fundamental role in many program analysis approaches, such as runtime verification, testing, monitoring, and specification mining. Execution traces are frequently parametric, i.e., they contain events…

Programming Languages · Computer Science 2015-07-01 Grigore Rosu , Feng Chen

By creating networks of biochemical pathways, communities of micro-organisms are able to modulate the properties of their environment and even the metabolic processes within their hosts. Next-generation high-throughput sequencing has led to…

Applications · Statistics 2023-03-28 Molly G. Hayes , Morgan G. I. Langille , Hong Gu

Multivariate meta-analysis of test accuracy studies when tests are evaluated in terms of sensitivity and specificity at more than one threshold represents an effective way to synthesize results by fully exploiting the data, if compared to…

Methodology · Statistics 2019-01-29 Annamaria Guolo , Duc Khanh To

Meta-learners and ensembles aim to combine a set of relevant yet diverse base models to improve predictive performance. However, determining an appropriate set of base models is challenging, especially in online environments where the…

Machine Learning · Computer Science 2021-11-30 Helen McKay , Nathan Griffiths , Phillip Taylor

Network meta-analysis of diagnostic test accuracy (NMA-DTA) is a relatively new field, involving combining evidence across studies to evaluate and compare the accuracy of different tests for a given condition. However, the methods proposed…

Methodology · Statistics 2026-04-23 Efthymia Derezea , Gabriel Rogers , Nicky J Welton , Hayley E Jones

It is becoming increasingly common for researchers to consider incorporating external information from large studies to improve the accuracy of statistical inference instead of relying on a modestly sized dataset collected internally. With…

Methodology · Statistics 2021-07-20 Tian Gu , Jeremy M. G. Taylor , Bhramar Mukherjee

Performance analysis is a critical step in the oft-repeated, iterative process of performance tuning of parallel programs. Per-process, per-thread traces (detailed logs of events with timestamps) enable in-depth analysis of parallel program…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-05-15 Abhinav Bhatele , Rakrish Dhakal , Alexander Movsesyan , Aditya K. Ranjan , Onur Cankur

Meta-learning, or "learning to learn," is a subfield of machine learning where the goal is to develop models and algorithms that can learn from various tasks and improve their learning process over time. Unlike traditional machine learning…

Machine Learning · Computer Science 2024-07-23 Mouad El Bouchattaoui

This article proposes a meta-learning method for estimating the conditional average treatment effect (CATE) from a few observational data. The proposed method learns how to estimate CATEs from multiple tasks and uses the knowledge for…

Machine Learning · Statistics 2023-05-22 Tomoharu Iwata , Yoichi Chikahara

Many machine learning models have important structural tuning parameters that cannot be directly estimated from the data. The common tactic for setting these parameters is to use resampling methods, such as cross--validation or the…

Machine Learning · Statistics 2014-05-28 Max Kuhn

This paper presents a Bayesian framework for assessing the adequacy of a model without the necessity of explicitly enumerating a specific alternate model. A test statistic is developed for tracking the performance of the model across…

Artificial Intelligence · Computer Science 2013-03-25 Kathryn Blackmond Laskey

Computational engineering generates knowledge through the analysis and interpretation of research data, which is produced by computer simulation. Supercomputers produce huge amounts of research data. To address a research question, a lot of…

Information Retrieval · Computer Science 2020-07-15 Björn Schembera , Dorothea Iglezakis

For many conditions, it is of clinical importance to know not just the ability of a test to distinguish between those with and without the disease, but also the sensitivity to detect disease at different stages: in particular, the test's…

Methodology · Statistics 2026-02-10 Efthymia Derezea , Nicky J Welton , Gabriel Rogers , Hayley E Jones

Typically, machine learning models are trained and evaluated without making any distinction between users (e.g, using traditional hold-out and cross-validation). However, this produces inaccurate performance metrics estimates in multi-user…

Machine Learning · Computer Science 2023-12-11 Enrique Garcia-Ceja , Luciano Garcia-Banuelos , Nicolas Jourdan

We develop a model-based methodology for integrating gene-set information with an experimentally-derived gene list. The methodology uses a previously reported sampling model, but takes advantage of natural constraints in the…

Methodology · Statistics 2015-06-02 Zhishi Wang , Qiuling He , Bret Larget , Michael A. Newton

In evidence synthesis, multilevel modeling approaches (MMAs) are commonly employed to combine aggregate data (AD) and individual participant data (IPD). These approaches rely on an aggregate outcome model that is ideally obtained by…

Methodology · Statistics 2026-02-18 Tran Trong Khoi Le , Marie-Felicia Béclin , Sivem Afach , Tat-Thang Vo

Hierarchical data with multiple observations per group is ubiquitous in empirical sciences and is often analyzed using mixed-effects regression. In such models, Bayesian inference gives an estimate of uncertainty but is analytically…

Machine Learning · Computer Science 2026-02-05 Alex Kipnis , Marcel Binz , Eric Schulz

Preprocessing forms an oft-neglected foundation for a wide range of statistical and scientific analyses. However, it is rife with subtleties and pitfalls. Decisions made in preprocessing constrain all later analyses and are typically…

Statistics Theory · Mathematics 2013-09-27 Alexander W. Blocker , Xiao-Li Meng

In this paper we will discuss metalearning and how we can go beyond the current classical learning paradigm. We will first address the importance of inductive biases in the learning process and what is at stake: the quantities of data…

Machine Learning · Computer Science 2024-01-02 Massinissa Hamidi , Aomar Osmani

In this paper, we present a visual analytics tool for enabling hypothesis-based evaluation of machine learning (ML) models. We describe a novel ML-testing framework that combines the traditional statistical hypothesis testing (commonly used…

Human-Computer Interaction · Computer Science 2020-08-28 Qianwen Wang , William Alexander , Jack Pegg , Huamin Qu , Min Chen