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This paper focuses on causal representation learning (CRL) under a general nonparametric latent causal model and a general transformation model that maps the latent data to the observational data. It establishes identifiability and…

Machine Learning · Computer Science 2024-02-15 Burak Varıcı , Emre Acartürk , Karthikeyan Shanmugam , Ali Tajer

The recent availability of huge, many-dimensional data sets, like those arising from genome-wide association studies (GWAS), provides many opportunities for strengthening causal inference. One popular approach is to utilize these…

Machine Learning · Statistics 2020-12-21 Ioan Gabriel Bucur , Tom Claassen , Tom Heskes

Dynamic models of biochemical networks typically consist of sets of non-linear ordinary differential equations involving states (concentrations or amounts of the components of the network) and parameters describing the reaction kinetics.…

Molecular Networks · Quantitative Biology 2014-03-07 Oana-Teodora Chis , Julio R. Banga , Eva Balsa-Canto

We consider the estimation of average treatment effects in observational studies and propose a new framework of robust causal inference with unobserved confounders. Our approach is based on distributionally robust optimization and proceeds…

Methodology · Statistics 2023-02-06 Dimitris Bertsimas , Kosuke Imai , Michael Lingzhi Li

This paper develops a Bayesian framework for robust causal inference from longitudinal observational data. Many contemporary methods rely on structural assumptions, such as factor models, to adjust for unobserved confounding, but they can…

Methodology · Statistics 2025-11-20 Angelos Alexopoulos , Nikolaos Demiris

Machine Learning explainability techniques have been proposed as a means of `explaining' or interrogating a model in order to understand why a particular decision or prediction has been made. Such an ability is especially important at a…

Machine Learning · Statistics 2022-02-28 Matthew J. Vowels

An old problem in multivariate statistics is that linear Gaussian models are often unidentifiable, i.e. some parameters cannot be uniquely estimated. In factor (component) analysis, an orthogonal rotation of the factors is unidentifiable,…

Machine Learning · Statistics 2023-05-04 Aapo Hyvärinen , Ilyes Khemakhem , Ricardo Monti

Causal discovery is a difficult problem that typically relies on strong assumptions on the data-generating model, such as non-Gaussianity. In practice, many modern applications provide multiple related views of the same system, which has…

Machine Learning · Computer Science 2025-09-29 Ambroise Heurtebise , Omar Chehab , Pierre Ablin , Alexandre Gramfort , Aapo Hyvärinen

Observed associations in a database may be due in whole or part to variations in unrecorded (latent) variables. Identifying such variables and their causal relationships with one another is a principal goal in many scientific and practical…

Machine Learning · Computer Science 2012-12-12 Ricardo Silva , Richard Scheines , Clark Glymour , Peter L. Spirtes

Community detection is a fundamental task in graph analysis, with methods often relying on fitting models like the Stochastic Block Model (SBM) to observed networks. While many algorithms can accurately estimate SBM parameters when the…

Machine Learning · Statistics 2025-06-05 Leonardo Martins Bianco , Christine Keribin , Zacharie Naulet

Causal mediation analysis is routinely conducted by applied researchers in a variety of disciplines. The goal of such an analysis is to investigate alternative causal mechanisms by examining the roles of intermediate variables that lie in…

Methodology · Statistics 2010-11-05 Kosuke Imai , Luke Keele , Teppei Yamamoto

Most of the regularization methods such as the LASSO have one (or more) regularization parameter(s), and to select the value of the regularization parameter is essentially equal to select a model. Thus, to obtain a model suitable for the…

Methodology · Statistics 2025-11-07 Sumito Kurata , Kei Hirose

Discovering the complete set of causal relations among a group of variables is a challenging unsupervised learning problem. Often, this challenge is compounded by the fact that there are latent or hidden confounders. When only observational…

Machine Learning · Computer Science 2021-01-19 Anqi Liu , Hao Liu , Tongxin Li , Saeed Karimi-Bidhendi , Yisong Yue , Anima Anandkumar

Recently, interpretable models called self-explaining models (SEMs) have been proposed with the goal of providing interpretability robustness. We evaluate the interpretability robustness of SEMs and show that explanations provided by SEMs…

Machine Learning · Computer Science 2020-07-03 Haizhong Zheng , Earlence Fernandes , Atul Prakash

This paper addresses the problem of learning linear dynamical systems from noisy observations. In this setting, existing algorithms either yield biased parameter estimates or have large sample complexities. We resolve these issues by…

Systems and Control · Electrical Eng. & Systems 2025-09-08 Yuyang Zhang , Xinhe Zhang , Jia Liu , Na Li

Designing learning algorithms that are resistant to perturbations of the underlying data distribution is a problem of wide practical and theoretical importance. We present a general approach to this problem focusing on unsupervised…

Machine Learning · Computer Science 2021-02-22 Andreas Maurer , Daniela A. Parletta , Andrea Paudice , Massimiliano Pontil

Computational and mathematical models rely heavily on estimated parameter values for model development. Identifiability analysis determines how well the parameters of a model can be estimated from experimental data. Identifiability analysis…

Quantitative Methods · Quantitative Biology 2021-02-12 Marissa Renardy , Denise Kirschner , Marisa Eisenberg

Recently, there has been considerable progress on designing algorithms with provable guarantees -- typically using linear algebraic methods -- for parameter learning in latent variable models. But designing provable algorithms for inference…

Machine Learning · Computer Science 2016-05-30 Sanjeev Arora , Rong Ge , Frederic Koehler , Tengyu Ma , Ankur Moitra

We investigate methods for parameter learning from incomplete data that is not missing at random. Likelihood-based methods then require the optimization of a profile likelihood that takes all possible missingness mechanisms into account.…

Methodology · Statistics 2012-07-02 Manfred Jaeger

Bayesian neural networks (BNNs) have recently regained a significant amount of attention in the deep learning community due to the development of scalable approximate Bayesian inference techniques. There are several advantages of using a…

Machine Learning · Statistics 2023-05-02 Aliaksandr Hubin , Geir Storvik