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COVID-19 remains a challenging global threat with ongoing waves of infections and clinical disease which have resulted millions of deaths and an enormous strain on health systems worldwide. Effective vaccines have been developed for the…

While several non-pharmacological measures have been implemented for a few months in an effort to slow the coronavirus disease (COVID-19) pandemic in the United States, the disease remains a danger in a number of counties as restrictions…

Physics and Society · Physics 2021-04-06 Chao Fan , Xiangqi Jiang , Ronald Lee , Ali Mostafavi

The outbreak of the novel coronavirus (COVID-19) is unfolding as a major international crisis whose influence extends to every aspect of our daily lives. Effective testing allows infected individuals to be quarantined, thus reducing the…

Machine Learning · Computer Science 2020-07-28 Rahul Singh , Fang Liu , Ness B. Shroff

Several recent studies have tackled the issue of optimal network immunization by providing efficient criteria to identify key nodes to be removed in order to break apart a network, thus preventing the occurrence of extensive epidemic…

Physics and Society · Physics 2018-02-22 Giovanni Strona , Claudio Castellano

Regional quarantine policies, in which a portion of a population surrounding infections are locked down, are an important tool to contain disease. However, jurisdictional governments -- such as cities, counties, states, and countries -- act…

Physics and Society · Physics 2021-06-10 Arun G. Chandrasekhar , Paul Goldsmith-Pinkham , Matthew O. Jackson , Samuel Thau

A pandemic is the spread of a disease across large regions, and can have devastating costs to the society in terms of health, economic and social. As such, the study of effective pandemic mitigation strategies can yield significant positive…

Artificial Intelligence · Computer Science 2024-10-02 Ari Gestetner , Buser Say

Infectious disease superspreading caused by heterogeneity in contact behavior has been observed to be an important determinant of epidemic dynamics and size in both empirical and theoretical settings. However, it has also been observed that…

Populations and Evolution · Quantitative Biology 2026-01-27 Ari S. Freedman , Bjarke F. Nielsen , Maximillian M. Nguyen , Laurent Hébert-Dufresne , Simon A. Levin

Discovering and isolating infected individuals is a cornerstone of epidemic control. Because many infectious diseases spread through close contacts, contact tracing is a key tool for case discovery and control. However, although contact…

Populations and Evolution · Quantitative Biology 2021-05-26 Sadamori Kojaku , Laurent Hébert-Dufresne , Enys Mones , Sune Lehmann , Yong-Yeol Ahn

Current efforts of modelling COVID-19 are often based on the standard compartmental models such as SEIR and their variations. As pre-symptomatic and asymptomatic cases can spread the disease between populations through travel, it is…

Physics and Society · Physics 2020-10-06 Xiaoye Ding , Shenyang Huang , Abby Leung , Reihaneh Rabbany

We analyse 'stop-and-go' containment policies that produce infection cycles as periods of tight lockdowns are followed by periods of falling infection rates. The subsequent relaxation of containment measures allows cases to increase again…

Theoretical Economics · Economics 2021-11-22 Claudius Gros , Daniel Gros

To contain the propagation of emerging diseases that are transmissible from human to human, non-pharmaceutical interventions (NPIs) aimed at reducing the interactions between humans are usually implemented. One example of the latter kind of…

Physics and Society · Physics 2021-05-21 Paulo Cesar Ventura , Alberto Aleta , Francisco Aparecido Rodrigues , Yamir Moreno

Non-pharmaceutical interventions (NPIs) are effective measures to contain a pandemic. Yet, such control measures commonly have a negative effect on the economy. Here, we propose a macro-level approach to support resolving this…

Neural and Evolutionary Computing · Computer Science 2021-02-25 Rohit Salgotra , Thomas Seidelmann , Dominik Fischer , Sanaz Mostaghim , Amiram Moshaiov

We consider the SEIR compartmental epidemic model subject to state and input constraints (a cap on the proportion of infectious individuals and limits on the allowed social distancing and quarantining measures, respectively). We present a…

Optimization and Control · Mathematics 2024-06-11 Willem Esterhuizen , Philipp Sauerteig , Stefan Streif , Karl Worthmann

We propose a novel testing and containment strategy in order to contain the spread of SARS-CoV2 while permitting large parts of the population to resume social and economic activity. Our approach recognises the fact that testing capacities…

Populations and Evolution · Quantitative Biology 2020-04-29 Jakob Jonnerby , Philip Lazos , Edwin Lock , Francisco Marmolejo-Cossío , C. Bronk Ramsey , Meghana Shukla , Divya Sridhar

COVID-19 has forced quarantine measures in several countries across the world. These measures have proven to be effective in significantly reducing the prevalence of the virus. To date, no effective treatment or vaccine is available. In the…

Populations and Evolution · Quantitative Biology 2020-12-02 Davide Faranda , Tommaso Alberti

In this study, we propose a time-dependent Susceptible-Exposed-Infected-Recovered (SEIR) model for the analysis of the SARS-CoV-2 epidemic outbreak in three different countries, the United States of America, Italy and Iceland using public…

Populations and Evolution · Quantitative Biology 2021-11-08 P. Girardi , C. Gaetan

The COVID-19 crisis highlighted the importance of non-medical interventions, such as testing and isolation of infected individuals, in the control of epidemics. Here, we show how to minimize testing needs while maintaining the number of…

Systems and Control · Electrical Eng. & Systems 2024-07-04 D. Acemoglu , A. Fallah , A. Giometto , D. Huttenlocher , A. Ozdaglar , F. Parise , S. Pattathil

We consider the SEIRS epidemiology model with such features of the COVID-19 outbreak as: abundance of unidentified infected individuals, limited time of immunity and a possibility of vaccination. The control of the pandemic dynamics is…

Populations and Evolution · Quantitative Biology 2026-03-31 J. Ilnytskyi , T. Patsahan

We are currently facing a highly critical case of a world-wide pandemic. The novel coronavirus (SARS-CoV-2, a.k.a. COVID-19) has proved to be extremely contagious and the original outbreak from Asia has now spread to all continents. This…

Physics and Society · Physics 2020-06-26 Priyanka , Vicky Verma

Contact tracing is an important control strategy for containing Ebola epidemics. From a theoretical perspective, explicitly incorporating contact tracing with disease dynamics presents challenges, and population level effects of contact…

Populations and Evolution · Quantitative Biology 2015-11-10 Cameron Browne , Hayriye Gulbudak , Glenn Webb