Related papers: Bayesian Bi-clustering Methods with Applications i…
The problem of categorical data analysis in high dimensions is considered. A discussion of the fundamental difficulties of probability modeling is provided, and a solution to the derivation of high dimensional probability distributions…
Clustering in high-dimensions poses many statistical challenges. While traditional distance-based clustering methods are computationally feasible, they lack probabilistic interpretation and rely on heuristics for estimation of the number of…
We present a new model-based integrative method for clustering objects given both vectorial data, which describes the feature of each object, and network data, which indicates the similarity of connected objects. The proposed general model…
Biclustering is an unsupervised data mining technique that aims to unveil patterns (biclusters) from gene expression data matrices. In the framework of this thesis, we propose new biclustering algorithms for microarray data. The latter is…
We study the accuracy of Bayesian supervised method used to cluster individuals into genetically homogeneous groups on the basis of dominant or codominant molecular markers. We provide a formula relating an error criterion the number of…
Clustering algorithms are one of the main analytical methods to detect patterns in unlabeled data. Existing clustering methods typically treat samples in a dataset as points in a metric space and compute distances to group together similar…
This paper presents a new modeling strategy for joint unsupervised analysis of multiple high-throughput biological studies. As in Multi-study Factor Analysis, our goals are to identify both common factors shared across studies and…
A key problem in statistical modeling is model selection, how to choose a model at an appropriate level of complexity. This problem appears in many settings, most prominently in choosing the number ofclusters in mixture models or the number…
Data clustering is the process of identifying natural groupings or clusters within multidimensional data based on some similarity measure. Clustering is a fundamental process in many different disciplines. Hence, researchers from different…
Disease mapping is the field of spatial epidemiology interested in estimating the spatial pattern in disease risk across $n$ areal units. One aim is to identify units exhibiting elevated disease risks, so that public health interventions…
As data sets continue to grow in size and complexity, effective and efficient techniques are needed to target important features in the variable space. Many of the variable selection techniques that are commonly used alongside clustering…
The advances of next-generation sequencing technology have accelerated study of the microbiome and stimulated the high throughput profiling of metagenomes. The large volume of sequenced data has encouraged the rise of various studies for…
Maximum likelihood estimates (MLEs) are asymptotically normally distributed, and this property is used in meta-analyses to test the heterogeneity of estimates, either for a single cluster or for several sub-groups. More recently, MLEs for…
In order to identify clusters of objects with features transformed by unknown affine transformations, we develop a Bayesian cluster process which is invariant with respect to certain linear transformations of the feature space and able to…
Biclustering involves the simultaneous clustering of objects and their attributes, thus defining local two-way clustering models. Recently, efficient algorithms were conceived to enumerate all biclusters in real-valued datasets. In this…
Clustering consists of partitioning data objects into subsets called clusters according to some similarity criteria. This paper addresses a generalization called quasi-clustering that allows overlapping of clusters, and which we link to…
Unsupervised clustering of curves according to their shapes is an important problem with broad scientific applications. The existing model-based clustering techniques either rely on simple probability models (e.g., Gaussian) that are not…
Bayesian models are a powerful tool for studying complex data, allowing the analyst to encode rich hierarchical dependencies and leverage prior information. Most importantly, they facilitate a complete characterization of uncertainty…
Given a set of data, biclustering aims at finding simultaneous partitions in biclusters of its samples and of the features which are used for representing the samples. Consistent biclusterings allow to obtain correct classifications of the…
Clustering methods are a valuable tool for the identification of patterns in high dimensional data with applications in many scientific problems. However, quantifying uncertainty in clustering is a challenging problem, particularly when…