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Feature selection is a combinatorial optimization problem that is NP-hard. Conventional approaches often employ heuristic or greedy strategies, which are prone to premature convergence and may fail to capture subtle yet informative…

Machine Learning · Computer Science 2025-10-22 Yusi Fan , Tian Wang , Zhiying Yan , Chang Liu , Qiong Zhou , Qi Lu , Zhehao Guo , Ziqi Deng , Wenyu Zhu , Ruochi Zhang , Fengfeng Zhou

Due to the complexity of cancer, clustering algorithms have been used to disentangle the observed heterogeneity and identify cancer subtypes that can be treated specifically. While kernel based clustering approaches allow the use of more…

Machine Learning · Statistics 2018-11-21 Nora K. Speicher , Nico Pfeifer

In recent times, following the paradigm of DETR (DEtection TRansformer), query-based end-to-end instance segmentation (QEIS) methods have exhibited superior performance compared to CNN-based models, particularly when trained on large-scale…

Computer Vision and Pattern Recognition · Computer Science 2024-05-24 Dingwen Zhang , Hao Li , Diqi He , Nian Liu , Lechao Cheng , Jingdong Wang , Junwei Han

Machine learning methods with quantitative imaging features integration have recently gained a lot of attention for lung nodule classification. However, there is a dearth of studies in the literature on effective features ranking methods…

Image and Video Processing · Electrical Eng. & Systems 2020-03-17 Hina Shakir , Haroon Rasheed , Tariq Mairaj Rasool Khan

Prediction of patient survival using high-dimensional multi-omics data requires systematic feature selection methods that ensure predictive performance, sparsity, and reliability for prognostic biomarker discovery. We developed a hybrid…

Genomics · Quantitative Biology 2026-04-15 John Zobolas , Anne-Marie George , Alberto López , Sebastian Fischer , Marc Becker , Tero Aittokallio

Combining the advantages of quantum computing and neural networks, quantum neural networks (QNNs) have gained considerable attention recently. However, because of the lack of quantum resource, it is costly to train QNNs. In this work, we…

Quantum Physics · Physics 2021-07-20 Tong Dou , Zhenwei Zhou , Kaiwei Wang , Shilu Yan , Wei Cui

Foundation models (FMs) are transforming computational pathology by offering new ways to analyze histopathology images. However, FMs typically require weeks of training on large databases, making their creation a resource-intensive process.…

Image and Video Processing · Electrical Eng. & Systems 2026-01-27 Till Nicke , Daniela Schacherer , Jan Raphael Schäfer , Natalia Artysh , Antje Prasse , André Homeyer , Andrea Schenk , Henning Höfener , Johannes Lotz

Feature selection that selects an informative subset of variables from data not only enhances the model interpretability and performance but also alleviates the resource demands. Recently, there has been growing attention on feature…

Neural and Evolutionary Computing · Computer Science 2023-03-15 Zahra Atashgahi , Xuhao Zhang , Neil Kichler , Shiwei Liu , Lu Yin , Mykola Pechenizkiy , Raymond Veldhuis , Decebal Constantin Mocanu

Cancer is one of the leading causes of death worldwide, making the development of rapid, minimally invasive, label-free and scalable diagnostic strategies a major challenge in modern oncology. In this context, spectroscopic liquid biopsy…

We propose a few-shot learning method for unsupervised feature selection, which is a task to select a subset of relevant features in unlabeled data. Existing methods usually require many instances for feature selection. However, sufficient…

Machine Learning · Computer Science 2021-07-05 Atsutoshi Kumagai , Tomoharu Iwata , Yasuhiro Fujiwara

Cancer, with its inherent heterogeneity, is commonly categorized into distinct subtypes based on unique traits, cellular origins, and molecular markers specific to each type. However, current studies primarily rely on complete multi-omics…

Machine Learning · Computer Science 2024-11-26 Yingxuan Ren , Fengtao Ren , Bo Yang

In this paper, we introduce an unsupervised cancer segmentation framework for histology images. The framework involves an effective contrastive learning scheme for extracting distinctive visual representations for segmentation. The encoder…

Computer Vision and Pattern Recognition · Computer Science 2022-06-20 Yilong Li , Yaqi Wang , Huiyu Zhou , Huaqiong Wang , Gangyong Jia , Qianni Zhang

Brain tumors analysis is important in timely diagnosis and effective treatment to cure patients. Tumor analysis is challenging because of tumor morphology like size, location, texture, and heteromorphic appearance in the medical images. In…

Image and Video Processing · Electrical Eng. & Systems 2022-02-14 Mirza Mumtaz Zahoor , Shahzad Ahmad Qureshi , Saddam Hussain Khan , Asifullah Khan

Generative learning is a powerful tool for representation learning, and shows particular promise for problems in biomedical imaging. However, in this context, sampling from the distribution is secondary to finding representations of real…

Image and Video Processing · Electrical Eng. & Systems 2022-09-07 Simon Myles Thomas

Tumor cells acquire different genetic alterations during the course of evolution in cancer patients. As a result of competition and selection, only a few subgroups of cells with distinct genotypes survive. These subgroups of cells are often…

Applications · Statistics 2018-03-20 Li Zeng , Joshua L. Warren , Hongyu Zhao

Unsupervised anomaly detection (UAD) presents a complementary alternative to supervised learning for brain tumor segmentation in magnetic resonance imaging (MRI), particularly when annotated datasets are limited, costly, or inconsistent. In…

Computer Vision and Pattern Recognition · Computer Science 2025-10-20 Gerard Comas-Quiles , Carles Garcia-Cabrera , Julia Dietlmeier , Noel E. O'Connor , Ferran Marques

Cancer is responsible for millions of deaths worldwide every year. Although significant progress has been achieved in cancer medicine, many issues remain to be addressed for improving cancer therapy. Appropriate cancer patient…

Machine Learning · Computer Science 2021-03-31 David Oniani , Chen Wang , Yiqing Zhao , Andrew Wen , Hongfang Liu , Feichen Shen

Feature selection is a widely used dimension reduction technique to select feature subsets because of its interpretability. Many methods have been proposed and achieved good results, in which the relationships between adjacent data points…

Machine Learning · Computer Science 2020-06-01 Yan Min , Mao Ye , Liang Tian , Yulin Jian , Ce Zhu , Shangming Yang

We propose a statistical framework to integrate radiological magnetic resonance imaging (MRI) and genomic data to identify the underlying radiogenomic associations in lower grade gliomas (LGG). We devise a novel imaging phenotype by…

Despite significant research efforts and advancements, cancer remains a leading cause of mortality. Early cancer prediction has become a crucial focus in cancer research to streamline patient care and improve treatment outcomes. Manual…

Computer Vision and Pattern Recognition · Computer Science 2024-08-19 Samta Rani , Tanvir Ahmad , Sarfaraz Masood , Chandni Saxena
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