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Ion Beam Analysis (IBA) is an established tool for material characterization, providing precise information on elemental composition, depth profiles, and structural information in the region near the surface of materials. However,…

Materials Science · Physics 2025-02-21 Tiago Fiorini da Silva

As global life expectancy increases, so does the burden of chronic diseases, yet individuals exhibit considerable variability in the rate at which they age. Identifying biomarkers that distinguish fast from slow ageing is crucial for…

Image and Video Processing · Electrical Eng. & Systems 2024-11-27 Kaustubh Chakradeo , Pernille Nielsen , Lise Mette Rahbek Gjerdrum , Gry Sahl Hansen , David A Duchêne , Laust H Mortensen , Majken K Jensen , Samir Bhatt

Limited DXA access hinders osteoporosis screening. This proof-of-concept study proposes using widely available knee X-rays for opportunistic Bone Mineral Density (BMD) estimation via deep learning, emphasizing robust uncertainty…

Computer Vision and Pattern Recognition · Computer Science 2025-05-29 Long Hui , Wai Lok Yeung

The increasing complexity of medical imaging data underscores the need for advanced anomaly detection methods to automatically identify diverse pathologies. Current methods face challenges in capturing the broad spectrum of anomalies, often…

Image and Video Processing · Electrical Eng. & Systems 2024-01-22 Cosmin I. Bercea , Benedikt Wiestler , Daniel Rueckert , Julia A. Schnabel

Normative aging trends of the brain can serve as an important reference in the assessment of neurological structural disorders. Such models are typically developed from longitudinal brain image data -- follow-up data of the same subject…

Computer Vision and Pattern Recognition · Computer Science 2021-06-29 Alphin J Thottupattu , Jayanthi Sivaswamy , Venkateswaran P. Krishnan

Hand modeling is critical for immersive VR/AR, action understanding, or human healthcare. Existing parametric models account only for hand shape, pose, or texture, without modeling the anatomical attributes like bone, which is essential for…

Computer Vision and Pattern Recognition · Computer Science 2021-06-22 Yuwei Li , Minye Wu , Yuyao Zhang , Lan Xu , Jingyi Yu

Blood-based biomarkers underpin clinical diagnosis and management, yet their interpretation relies largely on fixed population reference intervals that ignore stable, intra-patient variability. As such, population-based interpretation can…

Individuals age differently depending on a multitude of different factors such as lifestyle, medical history and genetics. Often, the global chronological age is not indicative of the true ageing process. An organ-based age estimation would…

Image and Video Processing · Electrical Eng. & Systems 2020-12-29 Karim Armanious , Sherif Abdulatif , Anish Rao Bhaktharaguttu , Thomas Küstner , Tobias Hepp , Sergios Gatidis , Bin Yang

Autism spectrum disorder is a developmental disorder characterized by significant social, communication, and behavioral challenges. Individuals diagnosed with autism, intellectual, and developmental disabilities (AUIDD) typically require…

Computers and Society · Computer Science 2021-11-25 Shadi Ghafghazi , Amarie Carnett , Leslie Neely , Arun Das , Paul Rad

Fetal ultrasounds are an essential part of prenatal care and can be used to estimate gestational age (GA). Accurate GA assessment is important for providing appropriate prenatal care throughout pregnancy and identifying complications such…

Predicting an individual's aging trajectory is a central challenge in preventative medicine and bioinformatics. While machine learning models can predict chronological age from biomarkers, they often fail to capture the dynamic,…

Machine Learning · Computer Science 2025-08-14 Nazira Dunbayeva , Yulong Li , Yutong Xie , Imran Razzak

Knee osteoarthritis (KOA) diagnosis from radiographs remains challenging due to the subtle morphological details that standard deep learning models struggle to capture effectively. We propose a novel multimodal framework that combines…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Marouane Tliba , Mohamed Amine Kerkouri , Yassine Nasser , Nour Aburaed , Aladine Chetouani , Ulas Bagci , Rachid Jennane

Predictive modeling using structural magnetic resonance imaging (MRI) data is a prominent approach to study brain-aging. Machine learning algorithms and feature extraction methods have been employed to improve predictions and explore…

Machine Learning · Computer Science 2025-01-20 Georgios Antonopoulos , Shammi More , Simon B. Eickhoff , Federico Raimondo , Kaustubh R. Patil

Accurate estimation of biological brain age from three dimensional (3D) T$_1$-weighted magnetic resonance imaging (MRI) is a critical imaging biomarker for identifying accelerated aging associated with neurodegenerative diseases. Effective…

Image and Video Processing · Electrical Eng. & Systems 2025-08-05 Mehreen Kanwal , Yunsik Son

Modern language models are evaluated on large benchmarks, which are difficult to make sense of, especially for model selection. Looking at the raw evaluation numbers themselves using a model-centric lens, we propose SimBA, a three phase…

Computation and Language · Computer Science 2025-10-22 Nishant Subramani , Alfredo Gomez , Mona Diab

Deep learning techniques have demonstrated great potential for accurately estimating brain age by analyzing Magnetic Resonance Imaging (MRI) data from healthy individuals. However, current methods for brain age estimation often directly…

Computer Vision and Pattern Recognition · Computer Science 2024-09-24 Fanzhe Yan , Gang Yang , Yu Li , Aiping Liu , Xun Chen

Age estimation has attracted attention for its various medical applications. There are many studies on human age estimation from biomedical images. However, there is no research done on mammograms for age estimation, as far as we know. The…

Computer Vision and Pattern Recognition · Computer Science 2022-07-14 Charitha Dissanayake Lekamlage , Fabia Afzal , Erik Westerberg , Abbas Cheddad

Lesion detection in brain Magnetic Resonance Images (MRIs) remains a challenging task. MRIs are typically read and interpreted by domain experts, which is a tedious and time-consuming process. Recently, unsupervised anomaly detection (UAD)…

Image and Video Processing · Electrical Eng. & Systems 2022-02-01 Marcel Bengs , Finn Behrendt , Max-Heinrich Laves , Julia Krüger , Roland Opfer , Alexander Schlaefer

Background: While deep learning technology, which has the capability of obtaining latent representations based on large-scale data, can be a potential solution for the discovery of a novel aging biomarker, existing deep learning methods for…

Machine Learning · Computer Science 2023-02-02 Seong-Eun Moon , Ji Won Yoon , Shinyoung Joo , Yoohyung Kim , Jae Hyun Bae , Seokho Yoon , Haanju Yoo , Young Min Cho

Chronological age of healthy people is able to be predicted accurately using deep neural networks from neuroimaging data, and the predicted brain age could serve as a biomarker for detecting aging-related diseases. In this paper, a novel 3D…

Image and Video Processing · Electrical Eng. & Systems 2021-06-08 Jian Cheng , Ziyang Liu , Hao Guan , Zhenzhou Wu , Haogang Zhu , Jiyang Jiang , Wei Wen , Dacheng Tao , Tao Liu
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