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Complex biological systems have been successfully modeled by biochemical and genetic interaction networks, typically gathered from high-throughput (HTP) data. These networks can be used to infer functional relationships between genes or…

Molecular Networks · Quantitative Biology 2015-04-13 Hyunghoon Cho , Bonnie Berger , Jian Peng

We propose an adaptive diffusion mechanism to optimize a global cost function in a distributed manner over a network of nodes. The cost function is assumed to consist of a collection of individual components. Diffusion adaptation allows the…

Optimization and Control · Mathematics 2015-06-03 Jianshu Chen , Ali H. Sayed

Information networks are ubiquitous and are ideal for modeling relational data. Networks being sparse and irregular, network embedding algorithms have caught the attention of many researchers, who came up with numerous embeddings algorithms…

Machine Learning · Computer Science 2020-09-25 Junshan Wang , Yilun Jin , Guojie Song , Xiaojun Ma

Network embedding aims to learn low-dimensional representations of nodes while capturing structure information of networks. It has achieved great success on many tasks of network analysis such as link prediction and node classification.…

Social and Information Networks · Computer Science 2020-04-03 Hansheng Xue , Luwei Yang , Wen Jiang , Yi Wei , Yi Hu , Yu Lin

While many unsupervised learning models focus on one family of tasks, either generative or discriminative, we explore the possibility of a unified representation learner: a model which uses a single pre-training stage to address both…

Computer Vision and Pattern Recognition · Computer Science 2023-07-18 Soumik Mukhopadhyay , Matthew Gwilliam , Vatsal Agarwal , Namitha Padmanabhan , Archana Swaminathan , Srinidhi Hegde , Tianyi Zhou , Abhinav Shrivastava

The evolutionary processes of complex systems contain critical information regarding their functional characteristics. The generation time of edges provides insights into the historical evolution of various networked complex systems, such…

Artificial Intelligence · Computer Science 2025-01-14 En Xu , Can Rong , Jingtao Ding , Yong Li

Diffusion, a fundamental internal mechanism emerging in many physical processes, describes the interaction among different objects. In many learning tasks with limited training samples, the diffusion connects the labeled and unlabeled data…

Machine Learning · Computer Science 2023-05-02 Tangjun Wang , Zehao Dou , Chenglong Bao , Zuoqiang Shi

Predicting the effect of amino acid mutations on enzyme thermodynamic stability (DDG) is fundamental to protein engineering and drug design. While recent deep learning approaches have shown promise, they often process sequence and structure…

Machine Learning · Computer Science 2025-11-10 Abigail Lin

Network embedding has recently emerged as a promising technique to embed nodes of a network into low-dimensional vectors. While fairly successful, most existing works focus on the embedding techniques for static networks. But in practice,…

Social and Information Networks · Computer Science 2020-10-28 Zenan Xu , Zijing Ou , Qinliang Su , Jianxing Yu , Xiaojun Quan , Zhenkun Lin

Drawing upon recent advances in language model alignment, we formulate offline Reinforcement Learning as a two-stage optimization problem: First pretraining expressive generative policies on reward-free behavior datasets, then fine-tuning…

Machine Learning · Computer Science 2024-10-31 Huayu Chen , Kaiwen Zheng , Hang Su , Jun Zhu

Foundation models, such as CNNs and ViTs, have powered the development of image representation learning. However, general guidance to model architecture design is still missing. Inspired by the connection between image representation…

Computer Vision and Pattern Recognition · Computer Science 2025-06-16 Zhemin Zhang , Xun Gong

Hypergraph neural networks (HNNs) using neural networks to encode hypergraphs provide a promising way to model higher-order relations in data and further solve relevant prediction tasks built upon such higher-order relations. However,…

Machine Learning · Computer Science 2023-02-16 Peihao Wang , Shenghao Yang , Yunyu Liu , Zhangyang Wang , Pan Li

Network embedding is an effective method to learn low-dimensional representations of nodes, which can be applied to various real-life applications such as visualization, node classification, and link prediction. Although significant…

Machine Learning · Computer Science 2020-03-31 Shixun Huang , Zhifeng Bao , Guoliang Li , Yanghao Zhou , J. Shane Culpepper

The analogy to heat diffusion has enhanced our understanding of information flow in graphs and inspired the development of Graph Neural Networks (GNNs). However, most diffusion-based GNNs emulate passive heat diffusion, which still suffers…

Machine Learning · Computer Science 2025-10-23 Mengying Jiang

The integration of multimodal data presents a challenge in cases when the study of a given phenomena by different instruments or conditions generates distinct but related domains. Many existing data integration methods assume a known…

Machine Learning · Statistics 2022-06-16 Andres F. Duque , Guy Wolf , Kevin R. Moon

Adaptive networks are well-suited to perform decentralized information processing and optimization tasks and to model various types of self-organized and complex behavior encountered in nature. Adaptive networks consist of a collection of…

Multiagent Systems · Computer Science 2013-05-07 Ali H. Sayed

Complex networks are frequently employed to model physical or virtual complex systems. When certain entities exist across multiple systems simultaneously, unveiling their corresponding relationships across the networks becomes crucial. This…

Physics and Society · Physics 2025-04-16 Rui Tang , Ziyun Yong , Shuyu Jiang , Xingshu Chen , Yaofang Liu , Yi-Cheng Zhang , Gui-Quan Sun , Wei Wang

Evolutionary artificial neural networks (EANNs) refer to a special class of artificial neural networks (ANNs) in which evolution is another fundamental form of adaptation in addition to learning. Evolutionary algorithms are used to adapt…

Artificial Intelligence · Computer Science 2016-11-17 Ajith Abraham

Sequence alignment has had an enormous impact on our understanding of biology, evolution, and disease. The alignment of biological {\em networks} holds similar promise. Biological networks generally model interactions between biomolecules…

Molecular Networks · Quantitative Biology 2019-11-25 Wayne B. Hayes

We addressed the problem of detecting the change in behavior of information diffusion from a small amount of observation data, where the behavior changes were assumed to be effectively reflected in changes in the diffusion parameter value.…

Social and Information Networks · Computer Science 2011-10-13 Kouzou Ohara , Kazumi Saito , Masahiro Kimura , Hiroshi Motoda