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Scientific progress is tightly coupled to the emergence of new research tools. Today, machine learning (ML)-especially deep learning (DL)-has become a transformative instrument for quantum science and technology. Owing to the intrinsic…

Quantum Physics · Physics 2025-08-15 Timothy Heightman , Marcin Płodzień

This chapter gives an introduction to qualitative and quantitative topological analyses of molecular electronic transitions. Among the possibilities for qualitatively describing how the electronic structure of a molecule is reorganized upon…

Chemical Physics · Physics 2018-11-27 Thibaud Etienne

Modeling electronic systems is an important application for quantum computers. In the context of materials science, an important open problem is the computational description of chemical reactions on surfaces. In this work, we outline a…

Molecular Dynamics (MD) simulations are vital for exploring complex systems in computational physics and chemistry. While machine learning methods dramatically reduce computational costs relative to ab initio methods, their accuracy in…

Materials Science · Physics 2025-07-18 Ivan Žugec , Tin Hadži Veljković , Maite Alducin , J. Iñaki Juaristi

Active learning is a machine learning method aiming at optimal design for model training. At variance with supervised learning, which labels all samples, active learning provides an improved model by labeling samples with maximal…

Recent years have witnessed the fast development of machine learning potentials (MLPs) and their widespread applications in chemistry, physics, and material science. By fitting discrete ab initio data faithfully to continuous and…

Chemical Physics · Physics 2025-05-13 Junfan Xia , Yaolong Zhang , Bin Jiang

Molecular representation is a critical element in our understanding of the physical world and the foundation for modern molecular machine learning. Previous molecular machine learning models have employed strings, fingerprints, global…

Machine Learning · Computer Science 2025-05-28 Daniil A. Boiko , Thiago Reschützegger , Benjamin Sanchez-Lengeling , Samuel M. Blau , Gabe Gomes

Machine learning has been applied to several problems in particle physics research, beginning with applications to high-level physics analysis in the 1990s and 2000s, followed by an explosion of applications in particle and event…

Computational Physics · Physics 2019-05-17 Kim Albertsson , Piero Altoe , Dustin Anderson , John Anderson , Michael Andrews , Juan Pedro Araque Espinosa , Adam Aurisano , Laurent Basara , Adrian Bevan , Wahid Bhimji , Daniele Bonacorsi , Bjorn Burkle , Paolo Calafiura , Mario Campanelli , Louis Capps , Federico Carminati , Stefano Carrazza , Yi-fan Chen , Taylor Childers , Yann Coadou , Elias Coniavitis , Kyle Cranmer , Claire David , Douglas Davis , Andrea De Simone , Javier Duarte , Martin Erdmann , Jonas Eschle , Amir Farbin , Matthew Feickert , Nuno Filipe Castro , Conor Fitzpatrick , Michele Floris , Alessandra Forti , Jordi Garra-Tico , Jochen Gemmler , Maria Girone , Paul Glaysher , Sergei Gleyzer , Vladimir Gligorov , Tobias Golling , Jonas Graw , Lindsey Gray , Dick Greenwood , Thomas Hacker , John Harvey , Benedikt Hegner , Lukas Heinrich , Ulrich Heintz , Ben Hooberman , Johannes Junggeburth , Michael Kagan , Meghan Kane , Konstantin Kanishchev , Przemysław Karpiński , Zahari Kassabov , Gaurav Kaul , Dorian Kcira , Thomas Keck , Alexei Klimentov , Jim Kowalkowski , Luke Kreczko , Alexander Kurepin , Rob Kutschke , Valentin Kuznetsov , Nicolas Köhler , Igor Lakomov , Kevin Lannon , Mario Lassnig , Antonio Limosani , Gilles Louppe , Aashrita Mangu , Pere Mato , Narain Meenakshi , Helge Meinhard , Dario Menasce , Lorenzo Moneta , Seth Moortgat , Mark Neubauer , Harvey Newman , Sydney Otten , Hans Pabst , Michela Paganini , Manfred Paulini , Gabriel Perdue , Uzziel Perez , Attilio Picazio , Jim Pivarski , Harrison Prosper , Fernanda Psihas , Alexander Radovic , Ryan Reece , Aurelius Rinkevicius , Eduardo Rodrigues , Jamal Rorie , David Rousseau , Aaron Sauers , Steven Schramm , Ariel Schwartzman , Horst Severini , Paul Seyfert , Filip Siroky , Konstantin Skazytkin , Mike Sokoloff , Graeme Stewart , Bob Stienen , Ian Stockdale , Giles Strong , Wei Sun , Savannah Thais , Karen Tomko , Eli Upfal , Emanuele Usai , Andrey Ustyuzhanin , Martin Vala , Justin Vasel , Sofia Vallecorsa , Mauro Verzetti , Xavier Vilasís-Cardona , Jean-Roch Vlimant , Ilija Vukotic , Sean-Jiun Wang , Gordon Watts , Michael Williams , Wenjing Wu , Stefan Wunsch , Kun Yang , Omar Zapata

The description of excited state dynamics in multichromophoric systems constitutes both a theoretical and experimental challenge in modern physical chemistry. An experimental protocol which can systematically characterize both coherent and…

Quantum Physics · Physics 2011-10-31 Joel Yuen-Zhou , Jacob J. Krich , Masoud Mohseni , Alán Aspuru-Guzik

In spite of decades of research, much remains to be discovered about folding: the detailed structure of the initial (unfolded) state, vestigial folding instructions remaining only in the unfolded state, the interaction of the molecule with…

Biological Physics · Physics 2018-11-26 Walter A. Simmons

Machine learning (ML) plays an important role in quantum chemistry, providing fast-to-evaluate predictive models for various properties of molecules. However, most existing ML models for molecular electronic properties use density…

Chemical Physics · Physics 2024-06-26 Hao Tang , Brian Xiao , Wenhao He , Pero Subasic , Avetik R. Harutyunyan , Yao Wang , Fang Liu , Haowei Xu , Ju Li

Machine learning algorithms learn a desired input-output relation from examples in order to interpret new inputs. This is important for tasks such as image and speech recognition or strategy optimisation, with growing applications in the IT…

Quantum Physics · Physics 2015-05-27 M. Schuld , I. Sinayskiy , F. Petruccione

Due to the intrinsic complexity and nonlinearity of chemical reactions, direct applications of traditional machine learning algorithms may face with many difficulties. In this study, through two concrete examples with biological background,…

Molecular Networks · Quantitative Biology 2020-06-02 Wuyue Yang , Liangrong Peng , Yi Zhu , Liu Hong

The potential of mean-field decomposition techniques in interpreting electronic transitions in molecules is explored, particularly, the usefulness of these for offering computational signatures of different classes of such excitations. When…

Chemical Physics · Physics 2022-02-14 Janus J. Eriksen

Preparing molecules at rest and in a highly pure quantum state is a long standing dream in chemistry and physics, so far achieved only for a select set of molecules in dedicated experimental setups. Here, a quantum-limited combination of…

Quantum Physics · Physics 2015-05-30 D. Leibfried

Highly excited vibrational states of an isolated molecule encode the vibrational energy flow pathways in the molecule. Recent studies have had spectacular success in understanding the nature of the excited states mainly due to the extensive…

Chemical Physics · Physics 2009-11-07 A. Semparithi , V. Charulatha , S. Keshavamurthy

In this introductory review, we focus on applications of quantum computation to problems of interest in physics and chemistry. We describe quantum simulation algorithms that have been developed for electronic-structure problems,…

Quantum Physics · Physics 2014-04-16 Man-Hong Yung , James D. Whitfield , Sergio Boixo , David G. Tempel , Alán Aspuru-Guzik

Machine learning methods have revolutionized the discovery process of new molecules and materials. However, the intensive training process of neural networks for molecules with ever-increasing complexity has resulted in exponential growth…

Emerging Technologies · Computer Science 2022-12-27 Hui Zhang , Jonathan Wei Zhong Lau , Lingxiao Wan , Liang Shi , Hong Cai , Xianshu Luo , Patrick Lo , Chee-Kong Lee , Leong-Chuan Kwek , Ai Qun Liu

Quantum computing applications are an emerging field in high-energy physics. Its ambitious fusion with artificial intelligence is expected to deliver significant efficiency gains over existing methods and/or enable computation from a…

Quantum Physics · Physics 2025-11-24 Hideki Okawa

Recent years have seen a significant increase in the use of machine intelligence for predicting electronic structure, molecular force fields, and the physicochemical properties of various condensed systems. However, substantial challenges…

Chemical Physics · Physics 2023-11-10 Jianzhong Wu , Mengyang Gu