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Leukemia diagnosis primarily relies on manual microscopic analysis of bone marrow morphology supported by additional laboratory parameters, making it complex and time consuming. While artificial intelligence (AI) solutions have been…

Although the notion of diagnostic problem has been extensively investigated in the context of static systems, in most practical applications the behavior of the modeled system is significantly variable during time. The goal of the paper is…

Artificial Intelligence · Computer Science 2013-03-25 Luigi Portinale

Deep learning has significantly advanced medical imaging analysis (MIA), achieving state-of-the-art performance across diverse clinical tasks. However, its success largely depends on large-scale, high-quality labeled datasets, which are…

Computer Vision and Pattern Recognition · Computer Science 2025-05-09 Cheng Jin , Zhengrui Guo , Yi Lin , Luyang Luo , Hao Chen

Gliomas are the most frequent primary brain tumors in adults. Glioma change detection aims at finding the relevant parts of the image that change over time. Although Deep Learning (DL) shows promising performances in similar change…

Computer Vision and Pattern Recognition · Computer Science 2023-01-27 Tommaso Di Noto , Meritxell Bach Cuadra , Chirine Atat , Eduardo Gamito Teiga , Monika Hegi , Andreas Hottinger , Patric Hagmann , Jonas Richiardi

Producing densely annotated data is a difficult and tedious task for medical imaging applications. To address this problem, we propose a novel approach to generate supervision for semi-supervised semantic segmentation. We argue that…

Image and Video Processing · Electrical Eng. & Systems 2022-10-10 Constantin Seibold , Simon Reiß , Jens Kleesiek , Rainer Stiefelhagen

Histopathology imaging is crucial for the diagnosis and treatment of skin diseases. For this reason, computer-assisted approaches have gained popularity and shown promising results in tasks such as segmentation and classification of skin…

Computer Vision and Pattern Recognition · Computer Science 2024-10-28 Luis Carlos Rivera Monroy , Leonhard Rist , Martin Eberhardt , Christian Ostalecki , Andreas Baur , Julio Vera , Katharina Breininger , Andreas Maier

Noise in data appears to be inevitable in most real-world machine learning applications and would cause severe overfitting problems. Not only can data features contain noise, but labels are also prone to be noisy due to human input. In this…

Machine Learning · Computer Science 2025-05-09 Weipeng Huang , Qin Li , Yang Xiao , Cheng Qiao , Tie Cai , Junwei Liang , Neil J. Hurley , Guangyuan Piao

Predicting the subcellular localization of proteins is an important and challenging problem. Traditional experimental approaches are often expensive and time-consuming. Consequently, a growing number of research efforts employ a series of…

Machine Learning · Computer Science 2017-04-19 Shixiang Wan , Quan Zou

Microscopic evaluation of white blood cell morphology is central to leukemia diagnosis, yet current deep learning models often act as black boxes, limiting clinical trust and adoption. We introduce HemBLIP, a vision language model designed…

Computer Vision and Pattern Recognition · Computer Science 2026-01-08 Julie van Logtestijn , Petru Manescu

Clinical dataset labels are rarely certain as annotators disagree and confidence is not uniform across cases. Typical aggregation procedures, such as majority voting, obscure this variability. In simple experiments on medical imaging…

As the frontline data for cancer diagnosis, microscopic pathology images are fundamental for providing patients with rapid and accurate treatment. However, despite their practical value, the deep learning community has largely overlooked…

Computer Vision and Pattern Recognition · Computer Science 2025-06-23 Sungrae Hong , Hyeongmin Park , Youngsin Ko , Sol Lee , Bryan Wong , Mun Yong Yi

Noisy training labels can hurt model performance. Most approaches that aim to address label noise assume label noise is independent from the input features. In practice, however, label noise is often feature or \textit{instance-dependent},…

Machine Learning · Computer Science 2023-07-12 Donna Tjandra , Jenna Wiens

Current state-of-the-art deep learning systems for visual object recognition and detection use purely supervised training with regularization such as dropout to avoid overfitting. The performance depends critically on the amount of labeled…

Computer Vision and Pattern Recognition · Computer Science 2015-04-16 Scott Reed , Honglak Lee , Dragomir Anguelov , Christian Szegedy , Dumitru Erhan , Andrew Rabinovich

Survival analysis stands as a pivotal process in cancer treatment research, crucial for predicting patient survival rates accurately. Recent advancements in data collection techniques have paved the way for enhancing survival predictions by…

Machine Learning · Computer Science 2024-07-26 Linhao Qu , Dan Huang , Shaoting Zhang , Xiaosong Wang

Medical image analysis using deep learning is often challenged by limited labeled data and high annotation costs. Fine-tuning the entire network in label-limited scenarios can lead to overfitting and suboptimal performance. Recently, prompt…

Computer Vision and Pattern Recognition · Computer Science 2023-08-10 Fan Bai , Ke Yan , Xiaoyu Bai , Xinyu Mao , Xiaoli Yin , Jingren Zhou , Yu Shi , Le Lu , Max Q. -H. Meng

Obtaining high-quality labeled datasets is often costly, requiring either human annotation or expensive experiments. In theory, powerful pre-trained AI models provide an opportunity to automatically label datasets and save costs.…

Machine Learning · Statistics 2025-10-21 Emmanuel J. Candès , Andrew Ilyas , Tijana Zrnic

Semi-supervised learning has made significant strides in the medical domain since it alleviates the heavy burden of collecting abundant pixel-wise annotated data for semantic segmentation tasks. Existing semi-supervised approaches enhance…

Computer Vision and Pattern Recognition · Computer Science 2021-12-03 Xu Zheng , Chong Fu , Haoyu Xie , Jialei Chen , Xingwei Wang , Chiu-Wing Sham

Determining cell identities in imaging sequences is an important yet challenging task. The conventional method for cell identification is via cell tracking, which is complex and can be time-consuming. In this study, we propose an innovative…

Quantitative Methods · Quantitative Biology 2024-03-05 Baiyang Dai , Jiamin Yang , Hari Shroff , Patrick La Riviere

Segmentation is a crucial analysis task in biomedical imaging. Given the diverse experimental settings in this field, the lack of generalization limits the use of deep learning in practice. Domain adaptation is a promising remedy: it…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Anwai Archit , Constantin Pape

Confounding pathology with normal anatomical variation remains a significant challenge in unsupervised medical-image anomaly detection, resulting in numerous false positives. To enhance integration of healthy variation, we augment the…

Quantitative Methods · Quantitative Biology 2026-03-09 P. Bilha Githinji , Xi Yuan , Ijaz Gul , Lian Zhang , Jinhao Xu , Zhenglin Chen , Peiwu Qin , Dongmei Yu
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