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In this paper, we consider the problem of answering count queries for genomic data subject to perfect privacy constraints. Count queries are often used in applications that collect aggregate (population-wide) information from biomedical…

Cryptography and Security · Computer Science 2023-07-04 Bo Jiang , Mohamed Seif , Ravi Tandon , Ming Li

Motivation: Researchers need a rich trove of genomic datasets that they can leverage to gain a better understanding of the genetic basis of the human genome and identify associations between phenotypes and specific parts of DNA. However,…

Cryptography and Security · Computer Science 2021-06-10 Nour Almadhoun Alserr , Gulce Kale , Onur Mutlu , Oznur Tastan , Erman Ayday

Genome sequencing technology has advanced at a rapid pace and it is now possible to generate highly-detailed genotypes inexpensively. The collection and analysis of such data has the potential to support various applications, including…

Cryptography and Security · Computer Science 2015-06-18 Muhammad Naveed , Erman Ayday , Ellen W. Clayton , Jacques Fellay , Carl A. Gunter , Jean-Pierre Hubaux , Bradley A. Malin , XiaoFeng Wang

Privacy-preserving genomic data sharing is prominent to increase the pace of genomic research, and hence to pave the way towards personalized genomic medicine. In this paper, we introduce ($\epsilon , T$)-dependent local differential…

Cryptography and Security · Computer Science 2021-02-16 Emre Yilmaz , Tianxi Ji , Erman Ayday , Pan Li

Rapid advances in human genomics are enabling researchers to gain a better understanding of the role of the genome in our health and well-being, stimulating hope for more effective and cost efficient healthcare. However, this also prompts a…

Cryptography and Security · Computer Science 2018-08-20 Alexandros Mittos , Bradley Malin , Emiliano De Cristofaro

The availability of genomic data is essential to progress in biomedical research, personalized medicine, etc. However, its extreme sensitivity makes it problematic, if not outright impossible, to publish or share it. As a result, several…

Genomics · Quantitative Biology 2022-01-19 Bristena Oprisanu , Georgi Ganev , Emiliano De Cristofaro

We study an information-theoretic privacy mechanism design, where an agent observes useful data $Y$ and wants to reveal the information to a user. Since the useful data is correlated with the private data $X$, the agent uses a privacy…

Information Theory · Computer Science 2025-01-22 Amirreza Zamani , Parastoo Sadeghi , Mikael Skoglund

In this paper, we study a stochastic disclosure control problem using information-theoretic methods. The useful data to be disclosed depend on private data that should be protected. Thus, we design a privacy mechanism to produce new data…

Information Theory · Computer Science 2021-03-24 Amirreza Zamani , Tobias J. Oechtering , Mikael Skoglund

Networks are important storage data structures now used to store personal information of individuals around the globe. With the advent of personal genome sequencing, networks are going to be used to store personal genomic sequencing of…

Social and Information Networks · Computer Science 2017-08-22 Komal Batool , Muaz A. Niazi

We consider the problem of maintaining sparsity in private distributed storage of confidential machine learning data. In many applications, e.g., face recognition, the data used in machine learning algorithms is represented by sparse…

Information Theory · Computer Science 2022-06-15 Marvin Xhemrishi , Maximilian Egger , Rawad Bitar

Motivation: Cutting the cost of DNA sequencing technology led to a quantum leap in the availability of genomic data. While sharing genomic data across researchers is an essential driver of advances in health and biomedical research, the…

Genomics · Quantitative Biology 2022-01-03 Nour Almadhoun Alserr , Ozgur Ulusoy , Erman Ayday , Onur Mutlu

When an individual's DNA is sequenced, sensitive medical information becomes available to the sequencing laboratory. A recently proposed way to hide an individual's genetic information is to mix in DNA samples of other individuals. We…

Information Theory · Computer Science 2024-11-05 Kayvon Mazooji , Roy Dong , Ilan Shomorony

Motivated by a real-life problem of sharing social network data that contain sensitive personal information, we propose a novel approach to release and analyze synthetic graphs in order to protect privacy of individual relationships…

Computation · Statistics 2016-09-26 Vishesh Karwa , Pavel N. Krivitsky , Aleksandra B. Slavković

Single nucleotide polymorphism (SNP) datasets are fundamental to genetic studies but pose significant privacy risks when shared. The correlation of SNPs with each other makes strong adversarial attacks such as masked-value reconstruction,…

Machine Learning · Computer Science 2025-10-08 Shadi Rahimian , Mario Fritz

Large genomic datasets are now created through numerous activities, including recreational genealogical investigations, biomedical research, and clinical care. At the same time, genomic data has become valuable for reuse beyond their…

Cryptography and Security · Computer Science 2021-12-28 Rajagopal Venkatesaramani , Zhiyu Wan , Bradley A. Malin , Yevgeniy Vorobeychik

People increasingly share personal information, including their photos and photo collections, on social media. This information, however, can compromise individual privacy, particularly as social media platforms use it to infer detailed…

Computer Vision and Pattern Recognition · Computer Science 2019-12-05 Jinghan Yang , Ayan Chakrabarti , Yevgeniy Vorobeychik

Deep generative models are often trained on sensitive data, such as genetic sequences, health data, or more broadly, any copyrighted, licensed or protected content. This raises critical concerns around privacy-preserving synthetic data, and…

This paper is motivated by applications of a Census Bureau interested in releasing aggregate socio-economic data about a large population without revealing sensitive information about any individual. The released information can be the…

Databases · Computer Science 2021-05-11 Ferdinando Fioretto , Pascal Van Hentenryck , Keyu Zhu

Deep generative models open new avenues for simulating realistic genomic data while preserving privacy and addressing data accessibility constraints. While previous studies have primarily focused on generating gene expression or haplotype…

Genomics · Quantitative Biology 2025-08-14 Sihan Xie , Thierry Tribout , Didier Boichard , Blaise Hanczar , Julien Chiquet , Eric Barrey

The emergence of social and technological networks has enabled rapid sharing of data and information. This has resulted in significant privacy concerns where private information can be either leaked or inferred from public data. The problem…

Data Structures and Algorithms · Computer Science 2015-11-20 Fragkiskos Koufogiannis , George Pappas
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