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In this work, we tackle the challenging problem of arbitrary image style transfer using a novel style feature representation learning method. A suitable style representation, as a key component in image stylization tasks, is essential to…

Computer Vision and Pattern Recognition · Computer Science 2022-11-08 Yuxin Zhang , Fan Tang , Weiming Dong , Haibin Huang , Chongyang Ma , Tong-Yee Lee , Changsheng Xu

The biological definition of Alzheimer's disease (AD) relies on multi-modal neuroimaging, yet the clinical utility of positron emission tomography (PET) is limited by cost and radiation exposure, hindering early screening at preclinical or…

Computer Vision and Pattern Recognition · Computer Science 2026-04-17 Tuo Liu , Shuijin Lin , Shaozhen Yan , Haifeng Wang , Jie Lu , Jianhua Ma , Chunfeng Lian

Performance of deep learning algorithms decreases drastically if the data distributions of the training and testing sets are different. Due to variations in staining protocols, reagent brands, and habits of technicians, color variation in…

Computer Vision and Pattern Recognition · Computer Science 2020-12-01 Abhijeet Patil , Mohd. Talha , Aniket Bhatia , Nikhil Cherian Kurian , Sammed Mangale , Sunil Patel , Amit Sethi

With the increase of computing power, machine learning models in medical imaging have been introduced to help in rending medical diagnosis and inspection, like hemophilia, a rare disorder in which blood cannot clot normally. Often, one of…

Computer Vision and Pattern Recognition · Computer Science 2024-09-19 Qianyu Fan

Cervical intraepithelial neoplasia (CIN) grade of histopathology images is a crucial indicator in cervical biopsy results. Accurate CIN grading of epithelium regions helps pathologists with precancerous lesion diagnosis and treatment…

Image and Video Processing · Electrical Eng. & Systems 2019-07-26 Yuan Xue , Qianying Zhou , Jiarong Ye , L. Rodney Long , Sameer Antani , Carl Cornwell , Zhiyun Xue , Xiaolei Huang

Deep neural networks are increasingly applied in automated histopathology. Yet, whole-slide images (WSIs) are often acquired at gigapixel sizes, rendering them computationally infeasible to analyze entirely at high resolution. Diagnostic…

Image and Video Processing · Electrical Eng. & Systems 2026-02-10 Tarun G , Naman Malpani , Gugan Thoppe , Sridharan Devarajan

Hyper-spectral images are images captured from a satellite that gives spatial and spectral information of specific region.A Hyper-spectral image contains much more number of channels as compared to a RGB image, hence containing more…

Computer Vision and Pattern Recognition · Computer Science 2022-06-22 Uphar Singh , Tushar Musale , Ranjana Vyas , O. P. Vyas

Atypical mitotic figures (AMFs) are important histopathological markers yet remain challenging to identify consistently, particularly under domain shift stemming from scanner, stain, and acquisition differences. We present a simple…

Computer Vision and Pattern Recognition · Computer Science 2025-08-29 Kaustubh Atey , Sameer Anand Jha , Gouranga Bala , Amit Sethi

Foundation diffusion models can generate photorealistic natural images, but adapting them to medical imaging remains challenging. In medical adaptation, limited labeled data can exacerbate hallucination-like and clinically implausible…

Computer Vision and Pattern Recognition · Computer Science 2026-05-14 Yunsung Chung , Alex El Darzi , Carlo El Khoury , Han Feng , Nassir Marrouche , Jihun Hamm

The task of classifying mammograms is very challenging because the lesion is usually small in the high resolution image. The current state-of-the-art approaches for medical image classification rely on using the de-facto method for ConvNets…

Computer Vision and Pattern Recognition · Computer Science 2021-01-21 Tao Wei , Angelica I Aviles-Rivero , Shuo Wang , Yuan Huang , Fiona J Gilbert , Carola-Bibiane Schönlieb , Chang Wen Chen

Computer assisted diagnosis in digital pathology is becoming ubiquitous as it can provide more efficient and objective healthcare diagnostics. Recent advances have shown that the convolutional Neural Network (CNN) architectures, a…

Image and Video Processing · Electrical Eng. & Systems 2022-01-05 Sruthi Krishna , Suganthi S. S , Shivsubramani Krishnamoorthy , Arnav Bhavsar

Detection of Alzheimer's Disease (AD) from neuroimaging data such as MRI through machine learning has been a subject of intense research in recent years. Recent success of deep learning in computer vision has progressed such research…

Computer Vision and Pattern Recognition · Computer Science 2019-06-05 Naimul Mefraz Khan , Marcia Hon , Nabila Abraham

In this work, we compare the performance of six state-of-the-art deep neural networks in classification tasks when using only image features, to when these are combined with patient metadata. We utilise transfer learning from networks…

Computer Vision and Pattern Recognition · Computer Science 2022-07-20 Spencer A. Thomas

In biomedical imaging, deep learning-based methods are state-of-the-art for every modality (virtual slides, MRI, etc.) In histopathology, these methods can be used to detect certain biomarkers or classify lesions. However, such techniques…

Computer Vision and Pattern Recognition · Computer Science 2023-03-10 Adrien Nivaggioli , Nicolas Pozin , Rémy Peyret , Stéphane Sockeel , Marie Sockeel , Nicolas Nerrienet , Marceau Clavel , Clara Simmat , Catherine Miquel

Early detection of newly emerging diseases, lesion severity assessment, differentiation of medical conditions and automated screening are examples for the wide applicability and importance of anomaly detection (AD) and unsupervised…

Computer Vision and Pattern Recognition · Computer Science 2025-09-17 Branko Mitic , Philipp Seeböck , Helmut Prosch , Georg Langs

Synthesizing realistic medical images provides a feasible solution to the shortage of training data in deep learning based medical image recognition systems. However, the quality control of synthetic images for data augmentation purposes is…

Computer Vision and Pattern Recognition · Computer Science 2020-08-27 Jiarong Ye , Yuan Xue , L. Rodney Long , Sameer Antani , Zhiyun Xue , Keith Cheng , Xiaolei Huang

Diabetic retinopathy (DR) grading plays a critical role in early clinical intervention and vision preservation. Recent explorations predominantly focus on visual lesion feature extraction through data processing and domain decoupling…

Artificial Intelligence · Computer Science 2025-12-01 Chunzheng Zhu , Yangfang Lin , Jialin Shao , Jianxin Lin , Yijun Wang

Immunohistochemical (IHC) staining highlights the molecular information critical to diagnostics in tissue samples. However, compared to H&E staining, IHC staining can be much more expensive in terms of both labor and the laboratory…

Computer Vision and Pattern Recognition · Computer Science 2023-03-14 Fangda Li , Zhiqiang Hu , Wen Chen , Avinash Kak

This study evaluates the generalisation capabilities of state-of-the-art histopathology foundation models on out-of-distribution multi-stain autoimmune Immunohistochemistry datasets. We compare 13 feature extractor models, including…

Computer Vision and Pattern Recognition · Computer Science 2024-10-30 Amaya Gallagher-Syed , Elena Pontarini , Myles J. Lewis , Michael R. Barnes , Gregory Slabaugh

Histopathology remains the gold standard for diagnosis of various cancers. Recent advances in computer vision, specifically deep learning, have facilitated the analysis of histopathology images for various tasks, including immune cell…

Quantitative Methods · Quantitative Biology 2023-11-02 Jakub R. Kaczmarzyk , Tahsin M. Kurc , Shahira Abousamra , Rajarsi Gupta , Joel H. Saltz , Peter K. Koo