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Deep learning methods have significantly advanced medical image segmentation, yet their success hinges on large volumes of manually annotated data, which require specialized expertise for accurate labeling. Additionally, these methods often…

Image and Video Processing · Electrical Eng. & Systems 2024-09-04 Wangang Cheng , Guanghua He , Keli Hu , Mingyu Fang , Liang Dong , Zhong Li , Hancan Zhu

Artificial Intelligence (AI) based image analysis has an immense potential to support diagnostic histopathology, including cancer diagnostics. However, developing supervised AI methods requires large-scale annotated datasets. A potentially…

In digital pathology, many image analysis tasks are challenged by the need for large and time-consuming manual data annotations to cope with various sources of variability in the image domain. Unsupervised domain adaptation based on…

Image and Video Processing · Electrical Eng. & Systems 2022-05-18 Nassim Bouteldja , Barbara Mara Klinkhammer , Tarek Schlaich , Peter Boor , Dorit Merhof

Accurate and fast histological staining is crucial in histopathology, impacting diagnostic precision and reliability. Traditional staining methods are time-consuming and subjective, causing delays in diagnosis. Digital pathology plays a…

Image and Video Processing · Electrical Eng. & Systems 2023-07-06 Marian Boktor , James E. D. Tweel , Benjamin R. Ecclestone , Jennifer Ai Ye , Paul Fieguth , Parsin Haji Reza

In Recent Years, Digital Technologies Have Made Significant Strides In Augmenting-Human-Health, Cognition, And Perception, Particularly Within The Field Of Computational-Pathology. This Paper Presents A Novel Approach To Enhancing The…

Computer Vision and Pattern Recognition · Computer Science 2025-07-24 Xiaoqian Hu

The unique nature of histopathology images opens the door to domain-specific formulations of image translation models. We propose a difficulty translation model that modifies colorectal histopathology images to be more challenging to…

Computer Vision and Pattern Recognition · Computer Science 2020-07-14 Jerry Wei , Arief Suriawinata , Xiaoying Liu , Bing Ren , Mustafa Nasir-Moin , Naofumi Tomita , Jason Wei , Saeed Hassanpour

Self-supervised learning has become a cornerstone in various areas, particularly histopathological image analysis. Image augmentation plays a crucial role in self-supervised learning, as it generates variations in image samples. However,…

Computer Vision and Pattern Recognition · Computer Science 2024-11-04 Hamid Manoochehri , Bodong Zhang , Beatrice S. Knudsen , Tolga Tasdizen

The detection of anomalous tissue regions (ATRs) within affected tissues is crucial in clinical diagnosis and pathological studies. Conventional automated ATR detection methods, primarily based on histology images alone, falter in cases…

Computer Vision and Pattern Recognition · Computer Science 2024-12-17 Kaichen Xu , Qilong Wu , Yan Lu , Yinan Zheng , Wenlin Li , Xingjie Tang , Jun Wang , Xiaobo Sun

Different types of staining highlight different structures in organs, thereby assisting in diagnosis. However, due to the impossibility of repeated staining, we cannot obtain different types of stained slides of the same tissue area.…

Image and Video Processing · Electrical Eng. & Systems 2024-04-17 Zexin Li , Yiyang Lin , Zijie Fang , Shuyan Li , Xiu Li

Histopathology foundation models (HFMs), pretrained on large-scale cancer datasets, have advanced computational pathology. However, their applicability to non-cancerous chronic kidney disease remains underexplored, despite coexistence of…

Virtual staining leverages computer-aided techniques to transfer the style of histochemically stained tissue samples to other staining types. In virtual staining of pathological images, maintaining strict structural consistency is crucial,…

Image and Video Processing · Electrical Eng. & Systems 2024-12-17 Bing Xiong , Yue Peng , RanRan Zhang , Fuqiang Chen , JiaYe He , Wenjian Qin

The diagnosis of prostate cancer is challenging due to the heterogeneity of its presentations, leading to the over diagnosis and treatment of non-clinically important disease. Accurate diagnosis can directly benefit a patient's quality of…

Histology imaging is an essential diagnosis method to finalize the grade and stage of cancer of different tissues, especially for breast cancer diagnosis. Specialists often disagree on the final diagnosis on biopsy tissue due to the complex…

Computer Vision and Pattern Recognition · Computer Science 2019-09-17 Yongxiang Huang , Albert Chi-shing Chung

Deep learning holds immense promise for transforming medical image analysis, yet its clinical generalization remains profoundly limited. A major barrier is data heterogeneity. This is particularly true in Magnetic Resonance Imaging, where…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Mehmet Yigit Avci , Pedro Borges , Virginia Fernandez , Paul Wright , Mehmet Yigitsoy , Sebastien Ourselin , Jorge Cardoso

Training a deep learning model to classify histopathological images is challenging, because of the color and shape variability of the cells and tissues, and the reduced amount of available data, which does not allow proper learning of those…

Computer Vision and Pattern Recognition · Computer Science 2023-07-25 Saypraseuth Mounsaveng , Issam Laradji , David Vázquez , Marco Perdersoli , Ismail Ben Ayed

Medical professionals, especially those in training, often depend on visual reference materials to support an accurate diagnosis and develop pattern recognition skills. However, existing resources may lack the diversity and accessibility…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Kanishk Choudhary

Advancement in digital pathology and artificial intelligence has enabled deep learning-based computer vision techniques for automated disease diagnosis and prognosis. However, WSIs present unique computational and algorithmic challenges.…

Computer Vision and Pattern Recognition · Computer Science 2021-06-15 Yash Sharma , Lubaina Ehsan , Sana Syed , Donald E. Brown

Digital pathology has advanced significantly over the last decade, with Whole Slide Images (WSIs) encompassing vast amounts of data essential for accurate disease diagnosis. High-resolution WSIs are essential for precise diagnosis but…

Image and Video Processing · Electrical Eng. & Systems 2024-08-28 Xuan Xu , Saarthak Kapse , Prateek Prasanna

The field of histology relies heavily on antiquated tissue processing and staining techniques that limit the efficiency of pathologic diagnoses of cancer and other diseases. Current staining and advanced labeling methods are often…

Deep learning based disease detection and segmentation algorithms promise to improve many clinical processes. However, such algorithms require vast amounts of annotated training data, which are typically not available in the medical context…

Image and Video Processing · Electrical Eng. & Systems 2021-11-02 Moritz Platscher , Jonathan Zopes , Christian Federau