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Strategies adopted globally to mitigate the threat of COVID-19 have primarily involved lockdown measures with substantial economic and social costs with varying degrees of success. Morbidity patterns of COVID-19 variants have a strong…

Populations and Evolution · Quantitative Biology 2022-01-19 Fatima-Zahra Jaouimaa , Daniel Dempsey , Suzanne van Osch , Stephen Kinsella , Kevin Burke , Jason Wyse , James Sweeney

The basic reproductive number -- $R_0$ -- is one of the most common and most commonly misapplied numbers in public health. Although often used to compare outbreaks and forecast pandemic risk, this single number belies the complexity that…

Populations and Evolution · Quantitative Biology 2020-04-15 Laurent Hébert-Dufresne , Benjamin M. Althouse , Samuel V. Scarpino , Antoine Allard

In this paper, we propose algorithms that leverage a known community structure to make group testing more efficient. We consider a population organized in disjoint communities: each individual participates in a community, and its infection…

Information Theory · Computer Science 2021-03-18 Pavlos Nikolopoulos , Tao Guo , Sundara Rajan Srinivasavaradhan , Christina Fragouli , Suhas Diggavi

Massive vaccination against pandemics such as Coronavirus SARS-CoV-2 presents several complexities. The criteria to assess public health policies are fundamental to distribute vaccines in an effective way in order to avoid as many…

Optimization and Control · Mathematics 2023-12-01 José Luis Sainz-Pardo , José Valero

In this research, we develop a framework to analyze the interaction between the economy and the Covid-19 pandemic using an extension of SIR epidemic model. At the outset, we assume there are two health related investments including general…

Optimization and Control · Mathematics 2022-02-14 Zachariah Sinkala , Vajira Manathunga , Bichaka Fayissa

Genomic surveillance of infectious diseases allows monitoring circulating and emerging variants and quantifying their epidemic potential. However, due to the high costs associated with genomic sequencing, only a limited number of samples…

Under limited available resources, strategies for mitigating the propagation of an epidemic such as random testing and contact tracing become inefficient. Here, we propose to accurately allocate the resources by computing over time an…

Physics and Society · Physics 2023-11-07 Gabriela Bayolo Soler , Miraine Dávila Felipe , Ghislaine Gayraud

Epidemics of infectious diseases posing a serious risk to human health have occurred throughout history. During recent epidemics there has been much debate about policy, including how and when to impose restrictions on behaviour.…

Theoretical Economics · Economics 2024-04-08 Simon K. Schnyder , John J. Molina , Ryoichi Yamamoto , Matthew S. Turner

The role of epidemiological models is crucial for informing public health officials during a public health emergency, such as the COVID-19 pandemic. However, traditional epidemiological models fail to capture the time-varying effects of…

Methodology · Statistics 2022-06-17 Adam Spannaus , Theodore Papamarkou , Samantha Erwin , J. Blair Christian

Early outbreak data analysis is critical for informing about their potential impact and interventions. However, data obtained early in outbreaks are often sensitive and subject to strict privacy restrictions. Thus, federated analysis, which…

Applications · Statistics 2026-01-27 Simon Busch-Moreno , Moritz U. G. Kraemer

COVID-19 pandemic has become a major threat to the country. Till date, well tested medication or antidote is not available to cure this disease. According to WHO reports, COVID-19 is a severe acute respiratory syndrome which is transmitted…

Populations and Evolution · Quantitative Biology 2020-04-03 Gaurav Pandey , Poonam Chaudhary , Rajan Gupta , Saibal Pal

Throughout the Covid-19 pandemic, a significant amount of effort had been put into developing techniques that predict the number of infections under various assumptions about the public policy and non-pharmaceutical interventions. While…

Computers and Society · Computer Science 2021-12-22 Sharare Zehtabian , Siavash Khodadadeh , Damla Turgut , Ladislau Bölöni

Repeated asymptomatic screening for SARS-CoV-2 promises to control spread of the virus but would require too many resources to implement at scale. Group testing is promising for screening more people with fewer test resources: multiple…

Populations and Evolution · Quantitative Biology 2020-11-18 Yifan Lin , Yuxuan Ren , Jingyuan Wan , Massey Cashore , Jiayue Wan , Yujia Zhang , Peter Frazier , Enlu Zhou

During the COVID-19 pandemic, case isolation emerged as a key non-pharmaceutical intervention in pandemic response. Its effectiveness hinges on the timing of isolation, which is often dictated by the onset of contagiousness. While…

Populations and Evolution · Quantitative Biology 2025-02-03 Jiahao Diao , Rebecca H. Chisholm , Nicholas Geard , James M. McCaw

Mathematical models are instrumental to forecast the spread of pathogens and to evaluate the effectiveness of non-pharmaceutical measures. A plethora of optimal strategies has been recently developed to minimize either the infected peak…

Dynamical Systems · Mathematics 2021-11-11 J. Sereno , A. L. Anderson , A. Ferramosca , E. A. Hernandez-Vargas , A. H. Gonzalez

The COVID-19 crisis has shown that we can only prevent the risk of mass contagion through timely, large-scale, coordinated, and decisive actions. However, frequently the models used by experts [from whom decision-makers get their main…

Applications · Statistics 2021-03-08 Mauricio Herrera

This study introduces a stochastic model of COVID-19 transmission tailored to the Colorado School of Mines campus and evaluates surveillance testing strategies within a university context. Enhancing the conventional SEIR framework with…

Applications · Statistics 2024-04-09 Laura Albrecht , Karin Leiderman , Suzanne Sindi , Douglas Nychka

During the COVID-19 pandemic, a massive number of attempts on the predictions of the number of cases and the other future trends of this pandemic have been made. However, they fail to predict, in a reliable way, the medium and long term…

Machine Learning · Computer Science 2020-11-30 Mert Nakıp , Onur Çopur , Cüneyt Güzeliş

Sustaining regular and infectious care during an infectious outbreak requires adequate management support for capacity allocation for regular and infectious patients. During the COVID-19 pandemic, hospitals faced severe challenges,…

Optimization and Control · Mathematics 2024-10-17 Stef Baas , Sander Dijkstra , Richard J. Boucherie , Anne Zander

We use daily data from Lombardy, the Italian region most affected by the COVID-19 outbreak, to calibrate a SIR model individually on each municipality. These are all covered by the same health system and, in the post-lockdown phase we focus…

Populations and Evolution · Quantitative Biology 2020-04-20 Pietro Battiston , Simona Gamba