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Statistical shape modeling (SSM) is a valuable and powerful tool to generate a detailed representation of complex anatomy that enables quantitative analysis and the comparison of shapes and their variations. SSM applies mathematics,…

Image and Video Processing · Electrical Eng. & Systems 2022-09-14 Krithika Iyer , Alan Morris , Brian Zenger , Karthik Karanth , Benjamin A Orkild , Oleksandre Korshak , Shireen Elhabian

Analyzing connections between brain regions of interest (ROI) is vital to detect neurological disorders such as autism or schizophrenia. Recent advancements employ graph neural networks (GNNs) to utilize graph structures in brains,…

Machine Learning · Computer Science 2024-01-03 Falih Gozi Febrinanto , Mujie Liu , Feng Xia

Blood circulation in the human brain is supplied through a network of cerebral arteries. If a clinician suspects a patient has a stroke or other cerebrovascular condition they order imaging tests. Neuroradiologists visually search the…

Human-Computer Interaction · Computer Science 2019-10-17 Aditeya Pandey , Harsh Shukla , Geoffrey S. Young , Lei Qin , Amir A. Zamani , Liangge Hsu , Raymond Huang , Cody Dunne , Michelle A. Borkin

This paper describes how realistic neuromorphic networks can have their connectivity properties fully characterized in analytical fashion. By assuming that all neurons have the same shape and are regularly distributed along the…

Disordered Systems and Neural Networks · Physics 2009-11-10 Luciano da F. Costa

Neuronal networks constitute a special class of dynamical systems, as they are formed by individual geometrical components, namely the neurons. In the existing literature, relatively little attention has been given to the influence of…

Neurons and Cognition · Quantitative Biology 2015-05-13 Sebastian Ahnert , Luciano da Fontoura Costa

Bayesian Networks (BNs) have become increasingly popular over the last few decades as a tool for reasoning under uncertainty in fields as diverse as medicine, biology, epidemiology, economics and the social sciences. This is especially true…

Machine Learning · Computer Science 2022-10-27 Neville K. Kitson , Anthony C. Constantinou , Zhigao Guo , Yang Liu , Kiattikun Chobtham

This paper presents methods to analyze functional brain networks and signals from graph spectral perspectives. The notion of frequency and filters traditionally defined for signals supported on regular domains such as discrete time and…

Neurons and Cognition · Quantitative Biology 2016-11-03 Weiyu Huang , Leah Goldsberry , Nicholas F. Wymbs , Scott T. Grafton , Danielle S. Bassett , Alejandro Ribeiro

Analysis of brain connectivity is important for understanding how information is processed by the brain. We propose a novel Bayesian vector autoregression (VAR) hierarchical model for analyzing brain connectivity in a resting-state fMRI…

Applications · Statistics 2021-12-09 Bertil Wegmann , Anders Lundquist , Anders Eklund , Mattias Villani

Understanding how distributed brain regions coordinate to produce behavior requires models that are both predictive and interpretable. We introduce Behavior-Adaptive Connectivity Estimation (BACE), an end-to-end framework that learns…

Neurons and Cognition · Quantitative Biology 2025-10-27 Mehrnaz Asadi , Sina Javadzadeh , Rahil Soroushmojdehi , S. Alireza Seyyed Mousavi , Terence D. Sanger

Alterations in structural brain laterality are reported in attention-deficit/hyperactivity disorder (ADHD). However, few studies examined differences within presentations of ADHD. We investigate asymmetry index (AI) across 13 subcortical…

Neurons and Cognition · Quantitative Biology 2020-10-27 Cintya Nirvana Dutta , Pamela K. Douglas , Hernando Ombao

Given the wide success of convolutional neural networks (CNNs) applied to natural images, researchers have begun to apply them to neuroimaging data. To date, however, exploration of novel CNN architectures tailored to neuroimaging data has…

Computer Vision and Pattern Recognition · Computer Science 2018-08-15 Pascal Sturmfels , Saige Rutherford , Mike Angstadt , Mark Peterson , Chandra Sripada , Jenna Wiens

Investigations of the human connectome have elucidated core features of adult structural networks, particularly the crucial role of hub-regions. However, little is known regarding network organisation of the healthy elderly connectome, a…

Neurons and Cognition · Quantitative Biology 2015-12-15 Alistair Perry , Wei Wen , Anton Lord , Anbupalam Thalamuthu , Perminder Sachdev , Michael Breakspear

This paper describes how realistic neuromorphic networks can have their connectivity fully characterized in analytical fashion. By assuming that all neurons have the same shape and are regularly distributed along the two-dimensional…

Disordered Systems and Neural Networks · Physics 2007-05-23 Luciano da Fontoura Costa , Marconi Soares Barbosa

Understanding how the spatial structure of blood vessel networks relates to their function in healthy and abnormal biological tissues could improve diagnosis and treatment for diseases such as cancer. New imaging techniques can generate…

Quantitative Methods · Quantitative Biology 2019-07-23 Helen M Byrne , Heather A Harrington , Ruth Muschel , Gesine Reinert , Bernadette J Stolz , Ulrike Tillmann

We present CaravelMetrics, a computational framework for automated cerebrovascular analysis that models vessel morphology through skeletonization-derived graph representations. The framework integrates atlas-based regional parcellation,…

Computer Vision and Pattern Recognition · Computer Science 2026-05-20 Daniele Falcetta , Liane S. Canas , Lorenzo Suppa , Matteo Pentassuglia , Jon Cleary , Marc Modat , Sébastien Ourselin , Maria A. Zuluaga

Purpose: To develop an age prediction model which is interpretable and robust to demographic and technological variances in brain MRI scans. Materials and Methods: We propose a transformer-based architecture that leverages self-supervised…

Computer Vision and Pattern Recognition · Computer Science 2025-06-24 Pengyu Kan , Craig Jones , Kenichi Oishi

It is of great interest to quantify the contributions of genetic variation to brain structure and function, which are usually measured by high-dimensional imaging data (e.g., magnetic resonance imaging). In addition to the variance, the…

Applications · Statistics 2020-05-05 Benjamin B. Risk , Hongtu Zhu

Deep graph-theoretic ideas in the context with the graph of the World Wide Web led to the definition of Google's PageRank and the subsequent rise of the most-popular search engine to date. Brain graphs, or connectomes, are being widely…

Neurons and Cognition · Quantitative Biology 2016-02-17 Balazs Szalkai , Balint Varga , Vince Grolmusz

Network analysis is rapidly becoming a standard tool for studying functional magnetic resonance imaging (fMRI) data. In this framework, different brain areas are mapped to the nodes of a network, whose links depict functional dependencies…

Neurons and Cognition · Quantitative Biology 2017-05-30 Rainer Kujala , Enrico Glerean , Raj Kumar Pan , Iiro P. Jääskeläinen , Mikko Sams , Jari Saramäki

Some evidence suggests that people with autism spectrum disorder exhibit patterns of brain functional dysconnectivity relative to their typically developing peers, but specific findings have yet to be replicated. To facilitate this…

Methodology · Statistics 2025-03-03 Hyoshin Kim , Sujit K. Ghosh , Emily C. Hector
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