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Compartmentalizing reagents within small droplets is promising for highly efficient conversion and simplified procedures in many biphasic chemical reactions. In this work, surface nanodroplets (i.e., less than 100 nm in their maximal…

Soft Condensed Matter · Physics 2021-06-24 Zhengxin Li , Akihito Kiyama , Xuehua Zhang , Hongbo Zeng

The compartmentalization of chemical reactions within droplets has advantages in low costs, reduced consumption of reagents and increased throughput. Reactions in small droplets have also been shown to greatly accelerate the rate of many…

Soft Condensed Matter · Physics 2020-07-27 Brendan P. Dyett , Xuehua Zhang

Nanodroplets on a solid surface (i.e. surface nanodroplets) have practical implications for high-throughput chemical and biological analysis, lubrications, lab-on-chip devices, and near-field imaging techniques. Oil nanodroplets can be…

Fluid Dynamics · Physics 2017-06-07 Xuehua Zhanga , Ziyang Lu , Huanshu Tan , Lei Bao , Yinghe He , Chao Sun , Detlef Lohse

Chemical reactions in small droplets are extensively explored to accelerate the discovery of new materials, increase efficiency and specificity in catalytic biphasic conversion and in high throughput analytics. In this work, we investigate…

Chemical Physics · Physics 2022-03-10 Zhengxin Li , Hongbo Zeng , Xuehua Zhang

Droplet-based interphase synthesis provides means to produce nanoparticles with low polydispersity by controlling mass transport through droplet dynamics. An experimentally validated model, based on coupled computational fluid dynamics with…

Fluid Dynamics · Physics 2023-04-17 Vivekananda Bal , Rajdip Bandyopadhyaya

The kinetic processes in nanoparticle-based catalysis are dominated by large fluctuations and spatiotemporal heterogeneities, in particular for diffusion-influenced reactions which are far from equilibrium. Here, we report results from…

Chemical Physics · Physics 2020-11-03 Yi-Chen Lin , Won Kyu Kim , Joachim Dzubiella

Droplet-based microfluidics has emerged as a powerful technology for the miniaturization and automation of biochemical assays. The replacement of surfactants by nanoparticles as interfacial stabilizers has gained increasing interest.…

Soft Condensed Matter · Physics 2019-06-21 Laura Andreina Chacon Orellana , Jean-Christophe Baret

The sensitive and reliable in-droplet chemical analysis benefits from the enhanced partition of an analyte into the droplets. This work, we will show that chemical reactions in surface nanodroplets can shift the partition of analytes from a…

Soft Condensed Matter · Physics 2021-10-04 Zixiang Wei , Jae Bem You , Hongbo Zeng , Xuehua Zhang

We introduce a new experimental approach to study the structural transitions of large numbers of nanoparticle-coated droplets as their volume is reduced. We use an emulsion system where the dispersed phase is slightly soluble in the…

Soft Condensed Matter · Physics 2012-09-28 Sujit S. Datta , Ho Cheung Shum , David A. Weitz

Droplets provide unique opportunities for the investigation of laser-induced surface chemistry. Chemical reactions on the surface of charged droplets are ubiquitous in nature and can provide critical insight into more efficient processes…

Rate of a reaction is enhanced by increase in temperature, partial pressure or the concentration of reactants, and/or via use of a catalyst or an enzyme. Whereas the former increases the probability of collision rate between different…

Soft Condensed Matter · Physics 2023-02-24 Nitish Singh , Animangsu Ghatak

The demixing of a binary fluid mixture, under gravity, is a two stage process. Initially droplets, or in general aggregates, grow diffusively by collecting supersaturation from the bulk phase. Subsequently, when the droplets have grown to a…

Statistical Mechanics · Physics 2014-12-01 Martin Rohloff , Tobias Lapp , Jürgen Vollmer

A combinative approach for chemical analysis makes it possible to distinguish a mixture of a large number of compounds from other mixtures in a single step. This work demonstrates a combinative analysis approach by using surface…

Soft Condensed Matter · Physics 2020-09-11 Zixiang Wei , Miaosi Li , Hongbo Zeng , Xuehua Zhang

The role of dimensionality (Euclidean versus fractal), spatial extent, boundary effects and system topology on the efficiency of diffusion-reaction processes involving two simultaneously-diffusing reactants is analyzed. We present…

Statistical Mechanics · Physics 2009-11-10 Jonathan L. Bentz , John J. Kozak , E. Abad , G. Nicolis

A wide variety of reactions are reported to be dramatically accelerated in aqueous microdroplets, making them a promising platform for environmentally clean chemical synthesis. However to fully utilize the microdroplets for accelerating…

Chemical Physics · Physics 2024-11-05 R. Allen LaCour , Joseph P. Heindel , Ruoqi Zhao , Teresa Head-Gordon

The hydrodynamic viscous fingering instability can be influenced by a simple viscosity changing chemical reaction of type A+B --> C, when a solution of reactant A is injected into a solution of B and a product C of different viscosity is…

Fluid Dynamics · Physics 2018-02-13 Priyanka Shukla , A. De Wit

Phase-separated liquid condensates can spatially organize and thereby regulate chemical processes. However, the physicochemical mechanisms underlying such regulation remain elusive as the intramolecular interactions responsible for phase…

Soft Condensed Matter · Physics 2024-03-11 Sudarshana Laha , Jonathan Bauermann , Frank Jülicher , Thomas C. T. Michaels , Christoph A. Weber

We present a new methodology for efficient and high-quality patterning of biological reagents for surface-based biological assays. The method relies on hydrodynamically confined nanoliter volumes of reagents to interact with the substrate…

Biomolecules · Quantitative Biology 2016-04-27 J. Autebert , J. F. Cors , David P. Taylor , G. V. Kaigala

We consider absorbing chemical reactions in a fluid flow modeled by the coupled advection-reaction-diffusion equations. In these systems, the interplay between chemical diffusion and fluid transportation causes the enhanced dissipation…

Analysis of PDEs · Mathematics 2022-07-27 Siming He , Alexander Kiselev

The dissolution of liquid nanodroplets is a crucial step in many applied processes, such as separation and dispersion in food industry, crystal formation of pharmaceutical products, concentrating and analysis in medical diagnosis, and drug…

Soft Condensed Matter · Physics 2022-09-08 Lei Bao , Vamsi Spandan , Yantao Yang , Brendan Dyetta , Roberto Verziccod , Detlef Lohseb , Xuehua Zhang
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