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When reading images, radiologists generate text reports describing the findings therein. Current state-of-the-art computer-aided diagnosis tools utilize a fixed set of predefined categories automatically extracted from these medical reports…

Computer Vision and Pattern Recognition · Computer Science 2022-10-10 Constantin Seibold , Simon Reiß , M. Saquib Sarfraz , Rainer Stiefelhagen , Jens Kleesiek

Many anomaly detection approaches, especially deep learning methods, have been recently developed to identify abnormal image morphology by only employing normal images during training. Unfortunately, many prior anomaly detection methods…

Medical multimodal learning faces significant challenges with missing modalities prevalent in clinical practice. Existing approaches assume equal contribution of modality and random missing patterns, neglecting inherent uncertainty in…

Machine Learning · Computer Science 2026-01-30 Linxiao Gong , Yang Liu , Lianlong Sun , Yulai Bi , Jing Liu , Xiaoguang Zhu

The precision of contouring target structures and organs-at-risk (OAR) in radiotherapy planning is crucial for ensuring treatment efficacy and patient safety. Recent advancements in deep learning (DL) have significantly improved OAR…

Image and Video Processing · Electrical Eng. & Systems 2024-09-30 Marvin Tom Teichmann , Manasi Datar , Lisa Kratzke , Fernando Vega , Florin C. Ghesu

Building a highly accurate predictive model for classification and localization of abnormalities in chest X-rays usually requires a large number of manually annotated labels and pixel regions (bounding boxes) of abnormalities. However, it…

Computer Vision and Pattern Recognition · Computer Science 2022-05-06 Yan Han , Chongyan Chen , Ahmed Tewfik , Benjamin Glicksberg , Ying Ding , Yifan Peng , Zhangyang Wang

The use of deep learning for medical imaging has seen tremendous growth in the research community. One reason for the slow uptake of these systems in the clinical setting is that they are complex, opaque and tend to fail silently. Outside…

Computer Vision and Pattern Recognition · Computer Science 2018-07-03 Terrance DeVries , Graham W. Taylor

In imaging inverse problems, one seeks to recover an image from missing/corrupted measurements. Because such problems are ill-posed, there is great motivation to quantify the uncertainty induced by the measurement-and-recovery process.…

Computer Vision and Pattern Recognition · Computer Science 2024-07-15 Jeffrey Wen , Rizwan Ahmad , Philip Schniter

In high-stakes risk prediction, quantifying uncertainty through interval-valued predictions is essential for reliable decision-making. However, standard evaluation tools like the receiver operating characteristic (ROC) curve and the area…

Machine Learning · Computer Science 2026-02-05 Yuqi Li , Matthew M. Engelhard

Radiologists highly desire fully automated versatile AI for medical imaging interpretation. However, the lack of extensively annotated large-scale multi-disease datasets has hindered the achievement of this goal. In this paper, we explore…

Computer Vision and Pattern Recognition · Computer Science 2024-04-09 Weiwei Cao , Jianpeng Zhang , Yingda Xia , Tony C. W. Mok , Zi Li , Xianghua Ye , Le Lu , Jian Zheng , Yuxing Tang , Ling Zhang

Anomaly detection in medical imaging is a challenging task in contexts where abnormalities are not annotated. This problem can be addressed through unsupervised anomaly detection (UAD) methods, which identify features that do not match with…

Image and Video Processing · Electrical Eng. & Systems 2023-09-07 Geoffroy Oudoumanessah , Carole Lartizien , Michel Dojat , Florence Forbes

Deep learning has shown tremendous progress in a wide range of digital pathology and medical image classification tasks. Its integration into safe clinical decision-making support requires robust and reliable models. However, real-world…

Image and Video Processing · Electrical Eng. & Systems 2024-08-19 Abdur R. Fayjie , Jutika Borah , Florencia Carbone , Jan Tack , Patrick Vandewalle

We propose a novel deep neural network architecture for normalcy detection in chest X-ray images. This architecture treats the problem as fine-grained binary classification in which the normal cases are well-defined as a class while leaving…

While deep learning has shown promise in the domain of disease classification from medical images, models based on state-of-the-art convolutional neural network architectures often exhibit performance loss due to dataset shift. Models…

Machine Learning · Computer Science 2020-01-14 Joseph D. Janizek , Gabriel Erion , Alex J. DeGrave , Su-In Lee

Formulating accurate and robust classification strategies is a key challenge of developing diagnostic and antibody tests. Methods that do not explicitly account for disease prevalence and uncertainty therein can lead to significant…

Methodology · Statistics 2022-02-01 Paul N. Patrone , Anthony J. Kearsley

Accurate image registration is essential in many medical imaging applications, yet most deep registration networks provide little indication of when or where their predictions are unreliable. Existing uncertainty estimation approaches, such…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Lin Tian , Xiaoling Hu , Juan Eugenio Iglesias

Semi-supervised learning relaxes the need of large pixel-wise labeled datasets for image segmentation by leveraging unlabeled data. A prominent way to exploit unlabeled data is to regularize model predictions. Since the predictions of…

Computer Vision and Pattern Recognition · Computer Science 2023-10-26 Sukesh Adiga , Jose Dolz , Herve Lombaert

Vulnerability to adversarial attacks is a well-known weakness of Deep Neural Networks. While most of the studies focus on natural images with standardized benchmarks like ImageNet and CIFAR, little research has considered real world…

Image and Video Processing · Electrical Eng. & Systems 2022-12-19 Salah Ghamizi , Maxime Cordy , Michail Papadakis , Yves Le Traon

Chest x-rays are the most common radiology studies for diagnosing lung and heart disease. Hence, a system for automated pre-reporting of pathologic findings on chest x-rays would greatly enhance radiologists' productivity. To this end, we…

Image and Video Processing · Electrical Eng. & Systems 2020-06-15 Adora M. DSouza , Anas Z. Abidin , Axel Wismüller

Chest radiography remains one of the most widely used imaging modalities for thoracic diagnosis, yet increasing imaging volumes and radiologist workload continue to challenge timely interpretation. In this work, we investigate the use of…

Medical events of interest, such as mortality, often happen at a low rate in electronic medical records, as most admitted patients survive. Training models with this imbalance rate (class density discrepancy) may lead to suboptimal…

Machine Learning · Computer Science 2022-08-02 Zepeng Huo , Xiaoning Qian , Shuai Huang , Zhangyang Wang , Bobak J. Mortazavi