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We define data analyses to monitor a change in R, the average number of secondary cases caused by a typical infected individual. The input dataset consists of incident cases partitioned into outbreaks, each initiated from a single index…

Populations and Evolution · Quantitative Biology 2016-04-27 Pavel Polyakov , Romulus Breban

The transmission of zoonotic diseases between animals and humans poses an increasing threat. Rabies is a prominent example with various instances globally, facilitated by a surplus of meso-predators (commonly, facultative synanthropic…

Information Retrieval · Computer Science 2025-01-28 Teddy Lazebnik , Yehuda Samuel , Jonathan Tichon , Roi Lapid , Roni King , Tomer Nissimian , Orr Spiegel

The effect of spatial correlations on the spread of infectious diseases was investigated using a stochastic SIR (Susceptible-Infective-Recovered) model on complex networks. It was found that in addition to the reduction of the effective…

Populations and Evolution · Quantitative Biology 2007-05-23 J. Verdasca , M. M. Telo da Gama , A. Nunes , N. R. Bernardino , J. M. Pacheco , M. C. Gomes

Mass-vaccination campaigns are an important strategy in the global fight against poliomyelitis and measles. The large-scale logistics required for these mass immunisation campaigns magnifies the need for research into the effectiveness and…

Populations and Evolution · Quantitative Biology 2014-05-28 Cameron Browne , Lydia Bourouiba , Robert Smith

Probabilistic models for infectious disease dynamics are useful for understanding the mechanism underlying the spread of infection. When the likelihood function for these models is expensive to evaluate, traditional likelihood-based…

Methodology · Statistics 2013-02-18 Roman Jandarov , Murali Haran , Ottar Bjørnstad , Bryan Grenfell

Quantitative magnetic resonance imaging might provide a more specific insight into disease process, progression and therapeutic response of multiple sclerosis. We present an extension of a previously published approach for the simultaneous…

The main idea in this paper is that the age associated with reported measles cases can be used to estimate the number of undetected measles infections. Somewhat surprisingly, even with age only to the nearest year, estimates of…

Populations and Evolution · Quantitative Biology 2022-02-24 Niket Thakkar

Multilevel regression and poststratification (MRP) is a computationally efficient indirect estimation method that can quickly produce improved population-adjusted estimates with limited data. Recent computational advancements allow…

Applications · Statistics 2025-05-07 Aja Sutton , Zack W. Almquist , Jon Wakefield

Individual-level health data are often not publicly available due to confidentiality; masked data are released instead. Therefore, it is important to evaluate the utility of using the masked data in statistical analyses such as regression.…

Applications · Statistics 2010-11-16 Yijie Zhou , Francesca Dominici , Thomas A. Louis

Malaria transmission in Madagascar is highly heterogeneous, exhibiting spatial, seasonal and long-term trends. Previous efforts to map malaria risk in Madagascar used prevalence data from Malaria Indicator Surveys. These cross-sectional…

Background As more regions approach malaria elimination, understanding how different interventions interact to reduce transmission becomes critical. The Lake Kariba area of Southern Province, Zambia, is part of a multi-country elimination…

Spatial individual-level models (ILMs) provide a flexible framework for modelling infectious disease transmission across populations with known locations. Bayesian inference for these models relies on Markov chain Monte Carlo (MCMC), which…

Computation · Statistics 2026-05-29 Yicheng Mao , Rob Deardon

In this paper, we extend the classical SIRS (Susceptible-Infectious-Recovered-Susceptible) model from mathematical epidemiology by incorporating a vaccinated compartment, V, accounting for an imperfect vaccine with waning efficacy over…

Populations and Evolution · Quantitative Biology 2025-01-30 Joseph Páez Chávez , Aytül Gökçe , Thomas Götz , Burcu Gürbüz

Mass campaigns with antimalarial drugs are potentially a powerful tool for local elimination of malaria, yet current diagnostic technologies are insufficiently sensitive to identify all individuals who harbor infections. At the same time,…

Populations and Evolution · Quantitative Biology 2016-02-17 Jaline Gerardin , Caitlin A. Bever , Busiku Hamainza , John M. Miller , Philip A. Eckhoff , Edward A. Wenger

In low- and middle-income countries (LMICs), accurate estimates of subnational health and demographic indicators are critical for guiding policy and identifying disparities. Many indicators of interest are proportions of binary outcomes and…

Applications · Statistics 2025-06-23 Jon Wakefield , Peter A. Gao , Geir-Arne Fuglstad , Zehang Richard Li

Malaria remains a significant public health challenge in many regions, necessitating robust predictive models to aid in its management and prevention. This study focuses on developing and evaluating time series models for forecasting…

Applications · Statistics 2025-11-19 Sujit K. Ghosh , Usha Ananthakumar , Praveen D. Chougale , Adithya B. Somaraj

In network-based SIS models of infectious disease transmission, infection can only occur between directly connected individuals. This constraint naturally gives rise to spatial correlations between the states of neighboring nodes, as the…

Statistical Mechanics · Physics 2026-03-18 Alexander Leibenzon , Samuel W. S. Johnson , Ruth E. Baker , Michael Assaf

Turkey hosts almost 3.5M refugees and has to face a humanitarian emergency of unprecedented levels. We use mobile phone data to map the mobility patterns of both Turkish and Syrian refugees, and use these patterns to build data-driven…

Populations and Evolution · Quantitative Biology 2019-01-15 Paolo Bosetti , Piero Poletti , Massimo Stella , Bruno Lepri , Stefano Merler , Manlio De Domenico

Measles is considered as a highly contagious disease that leads to serious complications around the world. Thus, the paper determined the trend and the five-year forecasted data of the Measles in the Philippines. This study utilized the…

Computers and Society · Computer Science 2021-01-06 Hidear Talirongan , Markdy Y. Orong , Florence Jean B. Talirongan

The tau statistic $\tau$ uses geolocation and, usually, symptom onset time to assess global spatiotemporal clustering from epidemiological data. We test different factors that could affect graphical hypothesis tests of clustering or bias…