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Whole-slide images (WSI) glomerulus segmentation is essential for accurately diagnosing kidney diseases. In this work, we propose a general and practical pipeline for glomerulus segmentation that effectively enhances both patch-level and…

Image and Video Processing · Electrical Eng. & Systems 2025-02-12 Quan Huu Cap

The condition of the Glomeruli, or filter sacks, in renal Direct Immunofluorescence (DIF) specimens is a critical indicator for diagnosing kidney diseases. A digital pathology system which digitizes a glass histology slide into a Whole…

Computer Vision and Pattern Recognition · Computer Science 2019-09-24 Can Peng , Kun Zhao , Arnold Wiliem , Teng Zhang , Peter Hobson , Anthony Jennings , Brian C. Lovell

The quantitative detection, segmentation, and characterization of glomeruli from high-resolution whole slide imaging (WSI) play essential roles in the computer-assisted diagnosis and scientific research in digital renal pathology.…

Computer Vision and Pattern Recognition · Computer Science 2022-06-02 Tianyuan Yao , Yuzhe Lu , Jun Long , Aadarsh Jha , Zheyu Zhu , Zuhayr Asad , Haichun Yang , Agnes B. Fogo , Yuankai Huo

Due to the increasing availability of whole slide scanners facilitating digitization of histopathological tissue, there is a strong demand for the development of computer based image analysis systems. In this work, the focus is on the…

Computer Vision and Pattern Recognition · Computer Science 2020-04-24 Michael Gadermayr , Ann-Kathrin Dombrowski , Barbara Mara Klinkhammer , Peter Boor , Dorit Merhof

Deep-learning techniques have been used widely to alleviate the labour-intensive and time-consuming manual annotation required for pixel-level tissue characterization. Our previous study introduced an efficient single dynamic network -…

Image and Video Processing · Electrical Eng. & Systems 2023-05-25 Haoju Leng , Ruining Deng , Zuhayr Asad , R. Michael Womick , Haichun Yang , Lipeng Wan , Yuankai Huo

The segmentation of kidney layer structures, including cortex, outer stripe, inner stripe, and inner medulla within human kidney whole slide images (WSI) plays an essential role in automated image analysis in renal pathology. However, the…

Image and Video Processing · Electrical Eng. & Systems 2023-09-07 Muhao Liu , Chenyang Qi , Shunxing Bao , Quan Liu , Ruining Deng , Yu Wang , Shilin Zhao , Haichun Yang , Yuankai Huo

Bag-based Multiple Instance Learning (MIL) approaches have emerged as the mainstream methodology for Whole Slide Image (WSI) classification. However, most existing methods adopt a segmented training strategy, which first extracts features…

Computer Vision and Pattern Recognition · Computer Science 2025-03-13 Jiangping Wen , Jinyu Wen , Meie Fang

Tissue examination and quantification in a 3D context on serial section whole slide images (WSIs) were laborintensive and time-consuming tasks. Our previous study proposed a novel registration-based method (Map3D) to automatically align…

Image and Video Processing · Electrical Eng. & Systems 2023-05-23 Peize Li , Ruining Deng , Yuankai Huo

The histopathological images contain a huge amount of information, which can make diagnosis an extremely timeconsuming and tedious task. In this study, we developed a completely automated system to detect regions of interest (ROIs) in whole…

Image and Video Processing · Electrical Eng. & Systems 2025-04-11 Mohammed Lamine Benomar , Nesma Settouti , Eric Debreuve , Xavier Descombes , Damien Ambrosetti

Current approaches for classification of whole slide images (WSI) in digital pathology predominantly utilize a two-stage learning pipeline. The first stage identifies areas of interest (e.g. tumor tissue), while the second stage processes…

Computer Vision and Pattern Recognition · Computer Science 2022-07-20 Marvin Teichmann , Andre Aichert , Hanibal Bohnenberger , Philipp Ströbel , Tobias Heimann

Accurate segmentation of glomerulus instances attains high clinical significance in the automated analysis of renal biopsies to aid in diagnosing and monitoring kidney disease. Analyzing real-world histopathology images often encompasses…

In digital pathology, the traditional method for deep learning-based image segmentation typically involves a two-stage process: initially segmenting high-resolution whole slide images (WSI) into smaller patches (e.g., 256x256, 512x512,…

Image and Video Processing · Electrical Eng. & Systems 2024-07-04 Yucheng Tang , Yufan He , Vishwesh Nath , Pengfeig Guo , Ruining Deng , Tianyuan Yao , Quan Liu , Can Cui , Mengmeng Yin , Ziyue Xu , Holger Roth , Daguang Xu , Haichun Yang , Yuankai Huo

In recent years, the availability of digitized Whole Slide Images (WSIs) has enabled the use of deep learning-based computer vision techniques for automated disease diagnosis. However, WSIs present unique computational and algorithmic…

Image and Video Processing · Electrical Eng. & Systems 2021-06-15 Yash Sharma , Aman Shrivastava , Lubaina Ehsan , Christopher A. Moskaluk , Sana Syed , Donald E. Brown

Segmentation has long been essential in computer vision due to its numerous real-world applications. However, most traditional deep learning and machine learning models need help to capture geometric features such as size and convexity of…

Image and Video Processing · Electrical Eng. & Systems 2024-12-02 Huy Trinh , Khang Tran , Nam Nguyen , Tri Cao , Binh Nguyen

Tumor segmentation stands as a pivotal task in cancer diagnosis. Given the immense dimensions of whole slide images (WSI) in histology, deep learning approaches for WSI classification mainly operate at patch-wise or superpixel-wise level.…

Computer Vision and Pattern Recognition · Computer Science 2024-02-22 Huaqian Wu , Clara Brémond-Martin , Kévin Bouaou , Cédric Clouchoux

Convolutional neural networks, the state of the art for image segmentation, have been successfully applied to histology images by many computational researchers. However, the translatability of this technology to clinicians and biological…

Image and Video Processing · Electrical Eng. & Systems 2021-01-19 Brendon Lutnick , David Manthey , Pinaki Sarder

Vertebral detection and segmentation are critical steps for treatment planning in spine surgery and radiation therapy. Accurate identification and segmentation are complicated in imaging that does not include the full spine, in cases with…

Image and Video Processing · Electrical Eng. & Systems 2023-11-17 Geoff Klein , Michael Hardisty , Cari Whyne , Anne L. Martel

In this paper, we propose a novel method for highly efficient follicular segmentation of thyroid cytopathological WSIs. Firstly, we propose a hybrid segmentation architecture, which integrates a classifier into Deeplab V3 by adding a…

Computer Vision and Pattern Recognition · Computer Science 2019-02-15 Siyan Tao , Yao Guo , Chuang Zhu , Huang Chen , Yue Zhang , Jie Yang , Jun Liu

In computational pathology, multiple instance learning (MIL) is widely used to circumvent the computational impasse in giga-pixel whole slide image (WSI) analysis. It usually consists of two stages: patch-level feature extraction and…

Image and Video Processing · Electrical Eng. & Systems 2023-09-21 Beidi Zhao , Wenlong Deng , Zi Han , Li , Chen Zhou , Zuhua Gao , Gang Wang , Xiaoxiao Li

Researchers working on computational analysis of Whole Slide Images (WSIs) in histopathology have primarily resorted to patch-based modelling due to large resolution of each WSI. The large resolution makes WSIs infeasible to be fed directly…

Computer Vision and Pattern Recognition · Computer Science 2021-06-08 Suvidha Tripathi , Satish Kumar Singh , Hwee Kuan Lee
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