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Recent ultrasound imaging modalities based on ultrasound computed tomography indicate a huge potential to detect pathologies is tissue due to altered biomechanical properties. Especially the imaging of speed-of-sound (SoS) distribution in…

Medical Physics · Physics 2021-07-05 Richard Rau , Dieter Schweizer , Valery Vishnevskiy , Orcun Goksel

Speed-of-sound (SoS) is an emerging ultrasound contrast modality, where pulse-echo techniques using conventional transducers offer multiple benefits. For estimating tissue SoS distributions, spatial domain reconstruction from relative…

Image and Video Processing · Electrical Eng. & Systems 2023-09-04 Can Deniz Bezek , Maxim Haas , Richard Rau , Orcun Goksel

Computed ultrasound tomography in echo mode (CUTE) allows determining the spatial distribution of speed-of-sound (SoS) inside tissue using handheld pulse-echo ultrasound (US). This technique is based on measuring the changing phase of…

Medical Physics · Physics 2020-06-01 Patrick Stähli , Maju Kuriakose , Martin Frenz , Michael Jaeger

In most photoacoustic (PA) measurements, variations in speed-of-sound (SOS) of the subject are neglected under the assumption of acoustic homogeneity. Biological tissue with spatially heterogeneous SOS cannot be accurately reconstructed…

Ultrasound (US) is widely used for clinical imaging applications thanks to its real-time and non-invasive nature. However, its lesion detectability is often limited in many applications due to the phase aberration artefact caused by…

Image and Video Processing · Electrical Eng. & Systems 2022-02-18 Shujaat Khan , Jaeyoung Huh , Jong Chul Ye

In ultrasound beamforming, focusing time delays are typically computed with a spatially constant speed-of-sound (SoS) assumption. A mismatch between beamforming and true medium SoS then leads to aberration artifacts. Other imaging…

Image and Video Processing · Electrical Eng. & Systems 2021-09-27 Xenia Augustin , Lin Zhang , Orcun Goksel

Photoacoustic (PA) image reconstruction involves acoustic inversion that necessitates the specification of the speed of sound (SoS) within the medium of propagation. Due to the lack of information on the spatial distribution of the SoS…

Image and Video Processing · Electrical Eng. & Systems 2024-06-05 Mengjie Shi , Tom Vercauteren , Wenfeng Xia

We describe a simple and fast technique to perform ultrasound differential phase contrast (DPC) imaging in arbitrarily thick scattering media. Though configured in a reflection geometry, DPC is based on transmission imaging and is a direct…

Image and Video Processing · Electrical Eng. & Systems 2021-04-07 Timothy D. Weber , Nikunj Khetan , Ruohui Yang , Jerome Mertz

For beamforming ultrasound (US) signals, typically a spatially constant speed-of-sound (SoS) is assumed to calculate delays. As SoS in tissue may vary relatively largely, this approximation may cause wavefront aberrations, thus degrading…

Image and Video Processing · Electrical Eng. & Systems 2019-12-12 Richard Rau , Dieter Schweizer , Valery Vishnevskiy , Orcun Goksel

Phase aberrations, despite degrading ultrasound images, also encode valuable information about the spatial distribution of the speed of sound in tissue. In pulse-echo ultrasound, we can quantify them by exploiting speckle correlations.…

Medical Physics · Physics 2025-11-20 Naiara Korta Martiartu , Michael Jaeger

Photoacoustic computed tomography (PACT) is a non-invasive imaging modality, similar to ultrasound, with wide-ranging medical applications. Conventional PACT images are degraded by wavefront distortion caused by the heterogeneous speed of…

Image and Video Processing · Electrical Eng. & Systems 2025-08-05 Tianao Li , Manxiu Cui , Cheng Ma , Emma Alexander

Conventional ultrasound (US) imaging employs the delay and sum (DAS) receive beamforming with dynamic receive focus for image reconstruction due to its simplicity and robustness. However, the DAS beamforming follows a geometrical method of…

Image and Video Processing · Electrical Eng. & Systems 2023-04-20 M. S. Asif , Gayathri Malamal , A. N. Madhavanunni , Vikram Melapudi , V Rahul , Abhijit Patil , Rajesh Langoju , Mahesh Raveendranatha Panicker

Accurate Speed-of-Sound (SoS) reconstruction from acoustic waveforms is a cornerstone of ultrasound computed tomography (USCT), enabling quantitative velocity mapping that reveals subtle anatomical details and pathological variations often…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Yujia Wu , Shuoqi Chen , Shiru Wang , Yucheng Tang , Petr Bruza , Geoffrey P. Luke

Most ultrasound (US) imaging techniques use spatially-constant speed-of-sound (SoS) values for beamforming. Having a discrepancy between the actual and used SoS value leads to aberration artifacts, e.g., reducing the image resolution, which…

Medical Physics · Physics 2022-08-18 Can Deniz Bezek , Mert Bilgin , Lin Zhang , Orcun Goksel

Shear-wave Elastography Imaging (SWEI) is a noninvasive imaging modality that provides tissue elasticity information by measuring the travelling speed of an induced shear-wave. It is commercially available on clinical ultrasound scanners…

Medical Physics · Physics 2022-04-21 Bhaskara Rao Chintada , Richard Rau , Orcun Goksel

Most ultrasound imaging techniques necessitate the fundamental step of converting temporal signals received from transducer elements into a spatial echogenecity map. This beamforming (BF) step requires the knowledge of speed-of-sound (SoS)…

Medical Physics · Physics 2022-11-22 Can Deniz Bezek , Orcun Goksel

Computed ultrasound tomography in echo mode generates maps of tissue speed of sound (SoS) from the shift of echoes when detected under varying steering angles. It solves a linearized inverse problem that requires regularization to…

Medical Physics · Physics 2026-04-23 Parisa Salemi Yolgunlu , Jules Blom , Naiara Korta Martiartu , Michael Jaeger

Speed-of-sound (SoS) is a novel imaging biomarker for assessing biomechanical characteristics of soft tissues. SoS imaging in pulse-echo mode using conventional ultrasound systems with hand-held transducers has the potential to enable new…

Medical Physics · Physics 2023-03-21 Dieter Schweizer , Richard Rau , Can Deniz Bezek , Rahel A. Kubik-Huch , Orcun Goksel

Accurate speed-of-sound (SoS) estimation is crucial for ultrasound image formation, yet conventional systems often rely on an assumed value for imaging. We propose to leverage conventional image analysis techniques and metrics as a novel…

Image and Video Processing · Electrical Eng. & Systems 2026-04-08 Roman Denkin , Orcun Goksel

This is the second article in a series of three dealing with the exploitation of speckle for aberration correction and reverberation compensation in reflection imaging. When probing heterogeneous media with waves, we have to cope with…

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