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Perfusion-weighted magnetic resonance imaging (MRI) is an imaging technique that allows one to measure tissue perfusion in an organ of interest through the injection of an intravascular paramagnetic contrast agent (CA). Due to a preference…

Computer Vision and Pattern Recognition · Computer Science 2017-08-28 Cagdas Ulas , Christine Preibisch , Jonathan Sperl , Thomas Pyka , Jayashree Kalpathy-Cramer , Bjoern Menze

Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is used to study microvascular structure and tissue perfusion. In DCE-MRI a bolus of gadolinium based contrast agent is injected into the blood stream and spatiotemporal changes…

Medical Physics · Physics 2020-09-22 Matti Hanhela , Mikko Kettunen , Olli Gröhn , Marko Vauhkonen , Ville Kolehmainen

Dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI) ideally requires a high spatial and high temporal resolution, but hardware limitations prevent acquisitions from simultaneously achieving both. Existing image reconstruction…

Signal Processing · Electrical Eng. & Systems 2025-11-18 Alexander J. Mertens , Hai-Ling Margaret Cheng

In this work we consider the image reconstruction problem of sparsely sampled dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI). DCE-MRI is a technique for acquiring a series of MR images before, during and after intravenous…

Image and Video Processing · Electrical Eng. & Systems 2020-02-24 Kati Niinimäki , Matti Hanhela , Ville Kolehmainen

Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is essential for breast cancer diagnosis due to its ability to characterize tissue through contrast agent kinetics. However, traditional DCE-MRI protocols require multiple…

Computer Vision and Pattern Recognition · Computer Science 2025-01-28 Ruben D. Fonnegra , Maria Liliana Hernández , Juan C. Caicedo , Gloria M. Díaz

Dynamic contrast-enhanced magnetic resonance imaging (DCE- MRI) is a widely used multi-phase technique routinely used in clinical practice. DCE and similar datasets of dynamic medical data tend to contain redundant information on the…

Purpose: To develop a framework to reconstruct large-scale volumetric dynamic MRI from rapid continuous and non-gated acquisitions, with applications to pulmonary and dynamic contrast enhanced (DCE) imaging. Theory and Methods: The problem…

Dynamic contrast-enhanced (DCE) MRI is an evolving imaging technique that provides a quantitative measure of pharmacokinetic (PK) parameters in body tissues, in which series of T1-weighted images are collected following the administration…

Computer Vision and Pattern Recognition · Computer Science 2018-06-13 Cagdas Ulas , Giles Tetteh , Michael J. Thrippleton , Paul A. Armitage , Stephen D. Makin , Joanna M. Wardlaw , Mike E. Davies , Bjoern H. Menze

Style transfer in DCE-MRI is a challenging task due to large variations in contrast enhancements across different tissues and time. Current unsupervised methods fail due to the wide variety of contrast enhancement and motion between the…

Image and Video Processing · Electrical Eng. & Systems 2023-10-23 Adam G. Tattersall , Keith A. Goatman , Lucy E. Kershaw , Scott I. K. Semple , Sonia Dahdouh

Dynamic MRI reconstruction from undersampled measurements is a challenging inverse problem that requires preserving both spatial reconstruction quality and temporal consistency across the frames of the cine series. While recent…

Image and Video Processing · Electrical Eng. & Systems 2026-05-19 Yongliang Sun , Siddhant Gautam , Chaoyan Huang , Nicole Seiberlich , Ismail Alkhouri , Saiprasad Ravishankar

We propose a novel deformation corrected compressed sensing (DC-CS) framework to recover dynamic magnetic resonance images from undersampled measurements. We introduce a generalized formulation that is capable of handling a wide class of…

Computer Vision and Pattern Recognition · Computer Science 2014-09-04 Sajan Goud Lingala , Edward DiBella , Mathews Jacob

Dynamic contrast-enhanced (DCE) MRI is essential for breast cancer diagnosis and treatment. However, its reliance on contrast agents introduces safety concerns, contraindications, increased cost, and workflow complexity. To this end, we…

Image and Video Processing · Electrical Eng. & Systems 2025-09-16 Sebastian Ibarra , Javier del Riego , Alessandro Catanese , Julian Cuba , Julian Cardona , Nataly Leon , Jonathan Infante , Karim Lekadir , Oliver Diaz , Richard Osuala

Purpose: To apply tracer kinetic models as temporal constraints during reconstruction of under-sampled dynamic contrast enhanced (DCE) MRI. Methods: A library of concentration v.s time profiles is simulated for a range of physiological…

Dynamic Contrast-Enhanced Magnetic Resonance Imaging (DCE-MRI) is a valuable tool to localize, characterize, and evaluate anomalous prostate tissue. Ultrafast gradient-echo acquisitions of MRI volumes are generated at regular time intervals…

Medical Physics · Physics 2017-10-11 Wuilian Torres , Leonardo Cordero , Miguel Martín-Landrove , Antonio Rueda-Toicen

Current deep learning reconstruction for accelerated cardiac cine MRI suffers from spatial and temporal blurring. We aim to improve image sharpness and motion delineation for cine MRI under high undersampling rates. A spatiotemporal…

Image and Video Processing · Electrical Eng. & Systems 2024-03-14 Shihan Qiu , Shaoyan Pan , Yikang Liu , Lin Zhao , Jian Xu , Qi Liu , Terrence Chen , Eric Z. Chen , Xiao Chen , Shanhui Sun

A method for perfusion imaging with DCE-MRI is developed based on two popular paradigms: the low-rank + sparse model for optimisation-based reconstruction, and the deep unfolding. A learnable algorithm derived from a proximal algorithm is…

Signal Processing · Electrical Eng. & Systems 2024-10-28 Ondřej Mokrý , Jiří Vitouš , Pavel Rajmic , Radovan Jiřík

Dynamic Magnetic Resonance Imaging (MRI) is a crucial non-invasive method used to capture the movement of internal organs and tissues, making it a key tool for medical diagnosis. However, dynamic MRI faces a major challenge: long…

Image and Video Processing · Electrical Eng. & Systems 2024-09-20 Tamir Shor , Chaim Baskin , Alex Bronstein

Intra-frame motion blurring, as a major challenge in free-breathing dynamic MRI, can be reduced if high temporal resolution can be achieved. To address this challenge, this work proposes a highly-accelerated 4D (3D+time) real-time MRI…

Medical Physics · Physics 2022-08-12 Li Feng

In the quantitative analysis of Dynamic Contrast-Enhanced Magnetic Resonance Imaging (DCE-MRI) compartment models allow to describe the uptake of contrast medium with biological meaningful kinetic parameters. As simple models often fail to…

Methodology · Statistics 2020-05-04 Julia C. Sommer , Volker J. Schmid

Dynamic Contrast-enhanced Magnetic Resonance Imaging (DCE-MRI) is an important tool for detecting subtle kinetic changes in cancerous tissue. Quantitative analysis of DCE-MRI typically involves the convolution of an arterial input function…

Applications · Statistics 2020-04-22 Volker J. Schmid , Brandon Whitcher , Anwar R. Padhani , Guang-Zhong Yang
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