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Related papers: On optimal two-stage testing of multiple mediators

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We present a selective sampling method designed to accelerate the training of deep neural networks. To this end, we introduce a novel measurement, the minimal margin score (MMS), which measures the minimal amount of displacement an input…

Machine Learning · Computer Science 2019-11-19 Berry Weinstein , Shai Fine , Yacov Hel-Or

High-dimensional biomarkers such as genomics are increasingly being measured in randomized clinical trials. Consequently, there is a growing interest in developing methods that improve the power to detect biomarker-treatment interactions.…

Methodology · Statistics 2021-04-30 Jixiong Wang , Ashish Patel , James M. S. Wason , Paul J. Newcombe

We first review existing sequential methods for estimating a binomial proportion. Afterward, we propose a new family of group sequential sampling schemes for estimating a binomial proportion with prescribed margin of error and confidence…

Statistics Theory · Mathematics 2013-11-05 Zhengjia Chen , Xinjia Chen

During the past few years, mediation analysis has gained increasing popularity across various research fields. The primary objective of mediation analysis is to examine the direct impact of exposure on outcome, as well as the indirect…

Computation · Statistics 2023-05-18 Haixiang Zhang , Xin Li

We study adaptive mesh selection for the solution of systems of initial value problems. The goal is a rigorous theoretical analysis of potential advantages of adaption. For an optimal method in the sense of the speed of convergence, we…

Numerical Analysis · Mathematics 2018-11-12 Boleslaw Kacewicz

The experimenter must perform a legitimate search in the entire set of feasible censoring schemes to identify the optimal type II progressive censoring scheme, when applied to a life-testing experiment. Current recommendations are limited…

Applications · Statistics 2025-07-29 Ujjwal Roy , Ritwik Bhattacharya

It is of substantial scientific interest to detect mediators that lie in the causal pathway from an exposure to a survival outcome. However, with high-dimensional mediators, as often encountered in modern genomic data settings, there is a…

Methodology · Statistics 2024-08-14 Tzu-Jung Huang , Zhonghua Liu , Ian W. McKeague

We study the problem of selecting the best heterogeneous treatment effect (HTE) estimator from a collection of candidates in settings where the treatment effect is fundamentally unobserved. We cast estimator selection as a multiple testing…

Machine Learning · Statistics 2025-11-25 Jiayi Guo , Zijun Gao

In this paper, we investigate the performance of selection cooperation in the presence of imperfect channel estimation. In particular, we consider a cooperative scenario with multiple relays and amplify-and- forward protocol over frequency…

Information Theory · Computer Science 2011-01-04 Mehdi Seyfi , Sami , Muhaidat , Jie Liang

Methods for the evaluation of the predictive accuracy of biomarkers with respect to survival outcomes subject to right censoring have been discussed extensively in the literature. In cancer and other diseases, survival outcomes are commonly…

Methodology · Statistics 2018-06-06 Yuan Wu , Xiaofei Wang , Jiaxing Lin , Beilin Jia , Kouros Owzar

A new method is proposed to explore sources of cross-site impact variance in multi-site trials of social interventions. With this approach, aggregate reports from participants in the treatment arm about the treatment experience are used to…

Applications · Statistics 2021-12-03 David R. Judkins , Gabriel Durham

We study the problem of approximate ranking from observations of pairwise interactions. The goal is to estimate the underlying ranks of $n$ objects from data through interactions of comparison or collaboration. Under a general framework of…

Statistics Theory · Mathematics 2019-06-26 Chao Gao

In this work we propose an adaptive multilevel version of subset simulation to estimate the probability of rare events for complex physical systems. Given a sequence of nested failure domains of increasing size, the rare event probability…

Numerical Analysis · Mathematics 2023-12-13 Daniel Elfverson , Robert Scheichl , Simon Weissmann , F. Alejandro DiazDelaO

This paper presents a novel estimation approach for cumulative link models, based on median bias reduction as developed in Kenne Pagui et al. (2017). The median bias reduced estimator is obtained as solution of an estimating equation based…

Methodology · Statistics 2020-09-16 Vincenzo Gioia , Euloge Clovis Kenne Pagui , Alessandra Salvan

An adaptive iterative decision multi-feedback detection algorithm with constellation constraints is proposed for multiuser multi-antenna systems. An enhanced detection and interference cancellation is performed by introducing multiple…

Information Theory · Computer Science 2013-04-24 Peng Li , Jingjing Liu , Rodrigo C. de Lamare

Many epidemiological questions concern potential interventions to alter the pathways presumed to mediate an association. For example, we consider a study that investigates the benefit of interventions in young adulthood for ameliorating the…

Methodology · Statistics 2020-07-14 Margarita Moreno-Betancur , Paul Moran , Denise Becker , George C Patton , John B Carlin

We study the problem of high-dimensional variable selection via some two-step procedures. First we show that given some good initial estimator which is $\ell_{\infty}$-consistent but not necessarily variable selection consistent, we can…

Statistics Theory · Mathematics 2008-10-10 Jian Zhang , Xinge Jessie Jeng , Han Liu

In recent years, pattern analysis plays an important role in data mining and recognition, and many variants have been proposed to handle complicated scenarios. In the literature, it has been quite familiar with high dimensionality of data…

Machine Learning · Computer Science 2018-11-09 Miao Cheng , Zunren Liu , Hongwei Zou , Ah Chung Tsoi

The Median-of-Means (MoM) is a robust estimator widely used in machine learning that is known to be (minimax) optimal in scenarios where samples are i.i.d. In more grave scenarios, samples are contaminated by an adversary that can inspect…

Machine Learning · Statistics 2025-10-10 Xabier de Juan , Santiago Mazuelas

In this paper, we first study the fundamental limit of clustering networks when a multi-layer network is present. Under the mixture multi-layer stochastic block model (MMSBM), we show that the minimax optimal network clustering error rate,…

Statistics Theory · Mathematics 2023-11-28 Zhongyuan Lyu , Ting Li , Dong Xia