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Identifying cell types and understanding their functional properties is crucial for unraveling the mechanisms underlying perception and cognition. In the retina, functional types can be identified by carefully selected stimuli, but this…

We propose a deep learning clustering method that exploits dense features from a segmentation network for emphysema subtyping from computed tomography (CT) scans. Using dense features enables high-resolution visualization of image regions…

Image and Video Processing · Electrical Eng. & Systems 2021-06-03 Weiyi Xie , Colin Jacobs , Bram van Ginneken

The activity of ensembles of simultaneously recorded neurons can be represented as a set of points in the space of firing rates. Even though the dimension of this space is equal to the ensemble size, neural activity can be effectively…

Neurons and Cognition · Quantitative Biology 2016-03-17 Luca Mazzucato , Alfredo Fontanini , Giancarlo La Camera

Irregularly sampled time series data are common in a variety of fields. Many typical methods for drawing insight from data fail in this case. Here we attempt to generalize methods for clustering trajectories to irregularly and sparsely…

Quantitative Methods · Quantitative Biology 2021-09-01 Gary K. Nave , Swati Padhee , Amanuel Alambo , Tanvi Banerjee , Nirmish Shah , Daniel M. Abrams

This study investigates remote synchronization in arbitrary network clusters of coupled nonlinear oscillators, a phenomenon inspired by neural synchronization in the brain. Employing a multi-faceted approach encompassing analytical,…

Systems and Control · Electrical Eng. & Systems 2025-05-01 Sanjeev Kumar Pandey , Neetish Patel

To study information processing in the brain, neuroscientists manipulate experimental stimuli while recording participant brain activity. They can then use encoding models to find out which brain "zone" (e.g. which region of interest,…

Neurons and Cognition · Quantitative Biology 2022-02-22 Mariya Toneva , Jennifer Williams , Anand Bollu , Christoph Dann , Leila Wehbe

Cluster synchronization in networks of coupled oscillators is the subject of broad interest from the scientific community, with applications ranging from neural to social and animal networks and technological systems. Most of these networks…

Dynamical Systems · Mathematics 2021-07-02 Matteo Lodi , Francesco Sorrentino , Marco Storace

Seizure activity is a ubiquitous and pernicious pathophysiology that, in principle, should yield to mathematical treatments of (neuronal) ensemble dynamics - and therefore interventions on stochastic chaos. A seizure can be characterised as…

Neurons process sensory stimuli efficiently, showing sparse yet highly variable ensemble spiking activity involving structured higher-order interactions. Notably, while neural populations are mostly silent, they occasionally exhibit highly…

Neurons and Cognition · Quantitative Biology 2025-07-17 Ulises Rodríguez-Domínguez , Hideaki Shimazaki

Computational methods have complemented experimental and clinical neursciences and led to improvements in our understanding of the nervous systems in health and disease. In parallel, neuromodulation in form of electric and magnetic…

Neurons and Cognition · Quantitative Biology 2014-08-13 Markus A. Dahlem , Sebastian Rode , Arne May , Naoya Fujiwara , Yoshito Hirata , Kazuyuki Aihara , Jürgen Kurths

Peripheral Nerve Stimulation (PNS) constrains the clinical performance of Magnetic Resonance and Particle Imaging (MRI and MPI) systems. Extensive magneto-stimulation studies have been carried out recently in the field of MPI, where typical…

Classification and clustering have been studied separately in machine learning and computer vision. Inspired by the recent success of deep learning models in solving various vision problems (e.g., object recognition, semantic segmentation)…

Machine Learning · Computer Science 2017-12-13 Ali Borji , Aysegul Dundar

We define the ``Pulse Synchronization'' problem that requires nodes to achieve tight synchronization of regular pulse events, in the settings of distributed computing systems. Pulse-coupled synchronization is a phenomenon displayed by a…

Distributed, Parallel, and Cluster Computing · Computer Science 2008-03-04 Ariel Daliot , Danny Dolev , Hanna Parnas

The learned weights of a neural network have often been considered devoid of scrutable internal structure. In this paper, however, we look for structure in the form of clusterability: how well a network can be divided into groups of neurons…

Neural and Evolutionary Computing · Computer Science 2021-03-08 Daniel Filan , Stephen Casper , Shlomi Hod , Cody Wild , Andrew Critch , Stuart Russell

Clustering has been a major research topic in the field of machine learning, one to which Deep Learning has recently been applied with significant success. However, an aspect of clustering that is not addressed by existing deep clustering…

Computer Vision and Pattern Recognition · Computer Science 2023-04-04 Ioannis Maniadis Metaxas , Georgios Tzimiropoulos , Ioannis Patras

Most decisions require information gathering from a stimulus presented with different gaps. Indeed, the brain process of this integration is rarely ambiguous. Recently, it has been claimed that humans can optimally integrate the information…

Neurons and Cognition · Quantitative Biology 2018-10-29 Maryam Tohidi-Moghaddam , Sajjad Zabbah , Farzaneh Olianezhad , Reza Ebrahimpour

In specific motifs of three recurrently connected neurons with probabilistic response, the spontaneous information flux, defined as the mutual information between subsequent states, has been shown to increase by adding ongoing white noise…

Neurons and Cognition · Quantitative Biology 2024-08-13 Claus Metzner , Achim Schilling , Andreas Maier , Patrick Krauss

Sepsis is a life-threatening condition caused by a dysregulated host response to infection. Recently, researchers have hypothesized that sepsis consists of a heterogeneous spectrum of distinct subtypes, motivating several studies to…

Applications · Statistics 2025-02-12 Alexander Dombowsky , David B. Dunson , Deng B. Madut , Matthew P. Rubach , Amy H. Herring

Deep neural networks trained to predict neural activity from visual input and behaviour have shown great potential to serve as digital twins of the visual cortex. Per-neuron embeddings derived from these models could potentially be used to…

One of the most intriguing dynamics in biological systems is the emergence of clustering, the self-organization into separated agglomerations of individuals. Several theories have been developed to explain clustering in, for instance,…

Physics and Society · Physics 2015-05-19 Michael Mäs , Andreas Flache , Dirk Helbing