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Balanced representation learning methods have been applied successfully to counterfactual inference from observational data. However, approaches that account for survival outcomes are relatively limited. Survival data are frequently…

Machine Learning · Statistics 2021-03-04 Paidamoyo Chapfuwa , Serge Assaad , Shuxi Zeng , Michael J. Pencina , Lawrence Carin , Ricardo Henao

This paper considers doing quantile regression on censored data using neural networks (NNs). This adds to the survival analysis toolkit by allowing direct prediction of the target variable, along with a distribution-free characterisation of…

Machine Learning · Statistics 2023-02-07 Tim Pearce , Jong-Hyeon Jeong , Yichen Jia , Jun Zhu

Survival analysis is crucial for many medical applications, but remains challenging for modern machine learning due to limited data, censoring, and the heterogeneity of tabular covariates. While the prior-fitted paradigm, which relies on…

Machine Learning · Computer Science 2026-05-14 Dmitrii Seletkov , Paul Hager , Georgios Kaissis , Rickmer Braren , Daniel Rueckert , Raphael Rehms

In this paper we consider how to evaluate survival distribution predictions with measures of discrimination. This is a non-trivial problem as discrimination measures are the most commonly used in survival analysis and yet there is no clear…

Machine Learning · Statistics 2022-03-10 Raphael Sonabend , Andreas Bender , Sebastian Vollmer

The i.i.d. censoring model for survival analysis assumes two independent sequences of i.i.d. positive random variables, $(T_i^*)_{1\le i\le n}$ and $(U_i)_{1\le i\le n}$. The data consists of observations on the random sequence…

Statistics Theory · Mathematics 2020-02-27 Ross A. Maller , Sidney I. Resnick

Survival analysis aims at modeling the relationship between covariates and event occurrence with some untracked (censored) samples. In implementation, existing methods model the survival distribution with strong assumptions or in a discrete…

Machine Learning · Computer Science 2023-05-25 Yu Ling , Weimin Tan , Bo Yan

Survival analysis plays a crucial role in understanding time-to-event (survival) outcomes such as disease progression. Despite recent advancements in causal mediation frameworks for survival analysis, existing methods are typically based on…

Methodology · Statistics 2026-05-07 Seungjun Ahn , Weijia Fu , Maaike van Gerwen , Lei Liu , Zhigang Li

Access to real clinical data is often restricted due to privacy obligations, creating significant barriers for healthcare research. Synthetic datasets provide a promising solution, enabling secure data sharing and model development.…

Machine Learning · Computer Science 2024-10-24 Nicholas I-Hsien Kuo , Blanca Gallego , Louisa Jorm

We consider the estimation of average treatment effects in observational studies and propose a new framework of robust causal inference with unobserved confounders. Our approach is based on distributionally robust optimization and proceeds…

Methodology · Statistics 2023-02-06 Dimitris Bertsimas , Kosuke Imai , Michael Lingzhi Li

Treatment switching in a randomized controlled trial is said to occur when a patient randomized to one treatment arm switches to another treatment arm during follow-up. This can occur at the point of disease progression, whereby patients in…

Methodology · Statistics 2021-03-24 Andrew Ying , Eric J. Tchetgen Tchetgen

We introduce the Mutual Information Machine (MIM), a probabilistic auto-encoder for learning joint distributions over observations and latent variables. MIM reflects three design principles: 1) low divergence, to encourage the encoder and…

Machine Learning · Computer Science 2020-02-24 Micha Livne , Kevin Swersky , David J. Fleet

For studying or reducing the bias of functionals of the Kaplan-Meier survival estimator, the jackknifing approach of Stute and Wang (1994) is natural. We have studied the behavior of the jackknife estimate of bias under different…

Methodology · Statistics 2013-12-17 Md Hasinur Rahaman Khan , J. Ewart H. Shaw

Survival analysis is widely used as a technique to model time-to-event data when some data is censored, particularly in healthcare for predicting future patient risk. In such settings, survival models must be both accurate and interpretable…

Machine Learning · Computer Science 2024-04-24 Mike Van Ness , Madeleine Udell

The restricted mean survival time is a clinically easy-to-interpret measure that does not require any assumption of proportional hazards. We focus on two ways to directly model the survival time and adjust the covariates. One is to…

Methodology · Statistics 2022-11-03 Keisuke Hanada , Junji Moriya , Masahiro Kojima

Finite mixture models have been widely used to model and analyze data from a heterogeneous populations. Moreover, data of this kind can be missing or subject to some upper and/or lower detection limits because of the restriction of…

Accurate prediction and identification of variables associated with outcomes or disease states are critical for advancing diagnosis, prognosis, and precision medicine in biomedical research. Regularized regression techniques, such as lasso,…

Applications · Statistics 2025-04-14 Xiaoru Dong , Apoorva Goyal , Muxuan Liang , Maigan A. Brusko , Todd M. Brusko , Rhonda Bacher

In the past decade, the increased availability of genome-wide association studies summary data has popularized Mendelian Randomization (MR) for conducting causal inference. MR analyses, incorporating genetic variants as instrumental…

Methodology · Statistics 2025-08-26 Zhongming Xie , Wanheng Zhang , Jingshen Wang , Chong Wu

Considering censored outcomes in survival analysis can lead to quite complex results in the model setting of causal inference. Causal inference has attracted a lot of attention over the past few years, but little research has been done on…

Methodology · Statistics 2025-09-11 Byeonghee Lee , Joonsung Kang

In this paper, we consider survival analysis with right-censored data which is a common situation in predictive maintenance and health field. We propose a model based on the estimation of two-parameter Weibull distribution conditionally to…

Methodology · Statistics 2020-02-24 Achraf Bennis , Sandrine Mouysset , Mathieu Serrurier

In dependently censored survival data, the usual assumption of independent censoring or an incorrect specification of the correlation between the event and censoring times can bias marginal survival inference. Likelihood-based estimation of…

Methodology · Statistics 2026-04-07 Hyun-Soo Zhang , Inkyung Jung , Chung Mo Nam