English
Related papers

Related papers: Hindering loads prompt clustered configurations th…

200 papers

Active matter systems evade the constraints of thermal equilibrium, leading to the emergence of intriguing collective behavior. A paradigmatic example is given by motor-filament mixtures, where the motion of motor proteins drives alignment…

Soft Condensed Matter · Physics 2024-09-11 Filippo De Luca , Ivan Maryshev , Erwin Frey

Diffusive transport of small molecules within the internal structures of biological and synthetic material systems is complex because the crowded environment presents chemical and physical barriers to mobility. We explored this mobility…

Soft Condensed Matter · Physics 2020-09-29 Rajarshi Guha , Subhadip Ghosh , Darrell Velegol , Peter J. Butler , Ayusman Sen , Jennifer L. Ross

We analyze experimental observations of microtubules undergoing small fluctuations about a "balance point" when mixed in solution of two different kinesin motor proteins, KLP61F and Ncd. It has been proposed that the microtubule movement is…

Cell Behavior · Quantitative Biology 2013-07-24 J. M. Deutsch , Ian P. Lewis

Kinesins are processive motor proteins that move along microtubules in a stepwise manner, and their motion is powered by the hydrolysis of ATP. Recent experiments have investigated the coupling between the individual steps of single kinesin…

Soft Condensed Matter · Physics 2009-11-10 Anatoly B. Kolomeisky , Evgeny B. Stukalin , Alex A. Popov

Cells control the size and organization of biomolecular condensates formed by liquid-liquid phase separation (LLPS), but multiple mechanisms likely contribute to this control and remain to be fully elucidated. Here we propose a…

Biological Physics · Physics 2026-04-10 Le Qiao , Peter Gispert , Lukas S. Stelzl , Friederike Schmid

A review is given on the studies of formation of light clusters and heavier fragments in heavy-ion collisions at incident energies from several tens of MeV/nucleon to several hundred MeV/nucleon, focusing on dynamical aspects and on…

Nuclear Theory · Physics 2019-03-05 Akira Ono

Kinesin and related motor proteins utilize ATP fuel to propel themselves along the external surface of microtubules in a processive and directional fashion. We show that the observed step-like motion is possible through time varying charge…

Biomolecules · Quantitative Biology 2007-05-23 A. Ciudad , J. M. Sancho , G. P. Tsironis

Traffic-like collective movements are observed at almost all levels of biological systems. Molecular motor proteins like, for example, kinesin and dynein, which are the vehicles of almost all intra-cellular transport in eukayotic cells,…

Biological Physics · Physics 2009-11-11 Debashish Chowdhury , Andreas Schadschneider , Katsuhiro Nishinari

Microtubule (MT) radial arrays or asters establish the internal topology of a cell by interacting with organelles and molecular motors. We proceed to understand the general pattern forming potential of aster-motor systems using a…

Subcellular Processes · Quantitative Biology 2025-08-15 Neha Khetan , Chaitanya A. Athale

Systems with two species of active molecular motors moving on (cytoskeletal) filaments into opposite directions are studied theoretically using driven lattice gas models. The motors can unbind from and rebind to the filaments. Two motors…

Statistical Mechanics · Physics 2007-05-23 Stefan Klumpp , Reinhard Lipowsky

Transitions between solid-like and fluid-like states in living tissues have been found in steps of embryonic development and in stages of disease progression. Our current understanding of these transitions has been guided by experimental…

Soft Condensed Matter · Physics 2024-11-20 Steven J. Chisolm , Emily Guo , Vignesh Subramaniam , Kyle D. Schulze , Thomas E. Angelini

We propose an alternative mechanism for intracellular cargo transport which results from motor induced longitudinal fluctuations of cytoskeletal microtubules (MT). The longitudinal fluctuations combined with transient cargo binding to the…

Soft Condensed Matter · Physics 2007-05-23 Igor M. Kulić , Philip C. Nelson

We consider an inhomogeneous strongly correlated system where external disorder divides it into mesoscopic cells.Strong inter-particle repulsion suppresses the quantum tunneling between cells and open a wide temperature range for incoherent…

Strongly Correlated Electrons · Physics 2007-05-23 Darwin Chang , Dung-Hai Lee

Kinesin is a molecular motor that transports cargo along microtubules. The results of many {\it in vitro} experiments on kinesin-1 are described by kinetic models \cite{Clancy11} in which one transition corresponds to the forward motion and…

Statistical Mechanics · Physics 2018-05-30 Gert Knoops , Carlo Vanderzande

Microscopic biological systems operate far from equilibrium, are subject to strong fluctuations, and are composed of many coupled components with interactions varying in nature and strength. Researchers are actively investigating the…

Statistical Mechanics · Physics 2023-12-25 Emma Lathouwers , David A. Sivak

Motivated by recent experimental results for the step sizes of dynein motor proteins, we develope a cellular automata model for intra-cellular traffic of dynein motors incorporating special features of the hindrance-dependent step size of…

Statistical Mechanics · Physics 2009-11-11 Ambarish Kunwar , Andreas Schadschneider , Debashish Chowdhury

We analyze the role of the force-dependent kinetics of motor proteins in the stability of antiparallel arrays of polar filaments, such as those in the mitotic spindle. We determine the possible stable structures and show that there exists…

Subcellular Processes · Quantitative Biology 2007-05-23 Otger Campas , Jaume Casademunt , Ignacio Pagonabarraga

Long-distance bidirectional transport of organelles depends on the motor proteins kinesin and dynein. Using quantitative data obtained from a fungal model system, we previously developed ASEP-models of bidirectional motion of motors along…

Statistical Mechanics · Physics 2012-11-22 Congping Lin , Peter Ashwin , Gero Steinberg

Theoretical studies on charge ordering phenomena in quarter-filled molecular (organic) conductors are reviewed. Extended Hubbard models including not only the on-site but also the inter-site Coulomb repulsion are constructed in a…

Strongly Correlated Electrons · Physics 2007-05-23 Hitoshi Seo , Jaime Merino , Hideo Yoshioka , Masao Ogata

Multi-cell cooperative processing with limited backhaul traffic is studied for cellular uplinks. Aiming at reduced backhaul overhead, a sparsity-regularized multi-cell receive-filter design problem is formulated. Both unstructured…

Information Theory · Computer Science 2015-10-16 Swayambhoo Jain , Seung-Jun Kim , Georgios B. Giannakis