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Diagnosing Autism Spectrum Disorder (ASD) is a challenging problem, and is based purely on behavioral descriptions of symptomology (DSM-5/ICD-10), and requires informants to observe children with disorder across different settings (e.g.…

Neurons and Cognition · Quantitative Biology 2020-03-04 Taban Eslami , Joseph S. Raiker , Fahad Saeed

Automated methods for Alzheimer's disease (AD) classification have the potential for great clinical benefits and may provide insight for combating the disease. Machine learning, and more specifically deep neural networks, have been shown to…

Existing deep learning models for functional MRI-based classification have limitations in network architecture determination (relying on experience) and feature space fusion (mostly simple concatenation, lacking mutual learning). Inspired…

Machine Learning · Computer Science 2025-08-19 Xiangxiang Cui , Min Zhao , Dongmei Zhi , Shile Qi , Vince D Calhoun , Jing Sui

The autism dataset is studied to identify the differences between autistic and healthy groups. For this, the resting-state Functional Magnetic Resonance Imaging (rs-fMRI) data of the two groups are analyzed, and networks of connections…

Image and Video Processing · Electrical Eng. & Systems 2022-12-05 Ramchandra Rimal , Mitchell Brannon , Yingxin Wang , Xin Yang

Autism Spectrum Disorder (ASD) is a severe neuropsychiatric disorder that affects intellectual development, social behavior, and facial features, and the number of cases is still significantly increasing. Due to the variety of symptoms ASD…

Image and Video Processing · Electrical Eng. & Systems 2021-10-11 Ryan Liu , Spencer He

In this study we focus on the problem of joint learning of multiple differential networks with function Magnetic Resonance Imaging (fMRI) data sets from multiple research centers. As the research centers may use different scanners and…

Methodology · Statistics 2021-06-08 Hao Chen , Ying Guo , Yong He , Dong Liu , Lei Liu , Xiao-Hua Zhou

The integration of diverse clinical modalities such as medical imaging and the tabular data extracted from patients' Electronic Health Records (EHRs) is a crucial aspect of modern healthcare. Integrative analysis of multiple sources can…

Computer Vision and Pattern Recognition · Computer Science 2025-04-22 Daniel Duenias , Brennan Nichyporuk , Tal Arbel , Tammy Riklin Raviv

Linguistic features have shown promising applications for detecting various cognitive impairments. To improve detection accuracies, increasing the amount of data or the number of linguistic features have been two applicable approaches.…

Computation and Language · Computer Science 2019-03-29 Zining Zhu , Jekaterina Novikova , Frank Rudzicz

Autism Spectrum Disorder(ASD) is a set of neurodevelopmental conditions that affect patients' social abilities. In recent years, many studies have employed deep learning to diagnose this brain dysfunction through functional MRI (fMRI).…

Image and Video Processing · Electrical Eng. & Systems 2021-10-26 Li Pan , Jundong Liu , Mingqin Shi , Chi Wah Wong , Kei Hang Katie Chan

A multi-task learning framework is proposed for optimizing a single deep neural network (DNN) for joint noise reduction (NR) and hearing loss compensation (HLC). A distinct training objective is defined for each task, and the DNN predicts…

Audio and Speech Processing · Electrical Eng. & Systems 2026-03-24 Philippe Gonzalez , Vera Margrethe Frederiksen , Torsten Dau , Tobias May

Cognitive neuroscience is enjoying rapid increase in extensive public brain-imaging datasets. It opens the door to large-scale statistical models. Finding a unified perspective for all available data calls for scalable and automated…

Machine Learning · Statistics 2019-05-16 Arthur Mensch , Julien Mairal , Danilo Bzdok , Bertrand Thirion , Gaël Varoquaux

In this paper, an innovative multi-modal deep learning model is proposed to deeply integrate heterogeneous information from medical images and clinical reports. First, for medical images, convolutional neural networks were used to extract…

Machine Learning · Computer Science 2024-05-29 Ziyan Yao , Fei Lin , Sheng Chai , Weijie He , Lu Dai , Xinghui Fei

We propose a novel deep neural network architecture to integrate imaging and genetics data, as guided by diagnosis, that provides interpretable biomarkers. Our model consists of an encoder, a decoder and a classifier. The encoder learns a…

Recent neuroimaging studies that focus on predicting brain disorders via modern machine learning approaches commonly include a single modality and rely on supervised over-parameterized models.However, a single modality provides only a…

This study investigates a hybrid method for text classification that integrates deep feature extraction from large language models, multi-scale fusion through feature pyramids, and structured modeling with graph neural networks to enhance…

Computation and Language · Computer Science 2025-11-11 Xiangchen Song , Yulin Huang , Jinxu Guo , Yuchen Liu , Yaxuan Luan

The opportunity to utilize complex functional data types for conducting classification tasks is emerging with the growing availability of imaging data. However, the tools capable of effectively managing imaging data are limited, let alone…

Methodology · Statistics 2025-07-22 Shuoyang Wang , Guanqun Cao , Yuan Huang

Early and accurate diagnosis of Alzheimer's disease (AD) remains a critical challenge in neuroimaging-based clinical decision support systems. In this work, we propose a novel hybrid deep learning framework that integrates Topological Data…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Faisal Ahmed

Fusing structural-functional images of the brain has shown great potential to analyze the deterioration of Alzheimer's disease (AD). However, it is a big challenge to effectively fuse the correlated and complementary information from…

Image and Video Processing · Electrical Eng. & Systems 2023-10-06 Qiankun Zuo , Junren Pan , Shuqiang Wang

Deep learning models for MRI classification face two recurring problems: they are typically limited by low sample size, and are abstracted by their own complexity (the "black box problem"). In this paper, we train a convolutional neural…

Quantitative Methods · Quantitative Biology 2020-05-28 Matthew Leming , Juan Manuel Górriz , John Suckling

Speech patterns have been identified as potential diagnostic markers for neuropsychiatric conditions. However, most studies only compare a single clinical group to healthy controls, whereas clinical practice often requires differentiating…