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There has been increasing interests in learning resting-state brain functional connectivity of autism disorders using functional magnetic resonance imaging (fMRI) data. The data in a standard brain template consist of over 200,000 voxel…

Methodology · Statistics 2016-03-22 Jichun Xie , Jian Kang

While the existence of low-dimensional embedding manifolds has been shown in patterns of collective motion, the current battery of nonlinear dimensionality reduction methods are not amenable to the analysis of such manifolds. This is mainly…

Numerical Analysis · Mathematics 2017-07-21 Kelum Gajamannage , Sachit Butail , Maurizio Porfiri , Erik M. Bollt

Mental disorders such as Autism Spectrum Disorders (ASD) are heterogeneous disorders that are notoriously difficult to diagnose, especially in children. The current psychiatric diagnostic process is based purely on the behavioural…

Machine Learning · Computer Science 2019-04-17 Taban Eslami , Vahid Mirjalili , Alvis Fong , Angela Laird , Fahad Saeed

Multi-manifold modeling is increasingly used in segmentation and data representation tasks in computer vision and related fields. While the general problem, modeling data by mixtures of manifolds, is very challenging, several approaches…

Computer Vision and Pattern Recognition · Computer Science 2012-10-08 G. Chen , S. Atev , G. Lerman

Functional connectivity (FC) analysis of resting-state fMRI data provides a framework for characterizing brain networks and their association with participant-level covariates. Due to the high dimensionality of neuroimaging data, standard…

Methodology · Statistics 2025-08-18 Wei Zhao , Brian J. Reich , Emily C. Hector

The last decade has witnessed an explosion in the development of models, theory and computational algorithms for "big data" analysis. In particular, distributed computing has served as a natural and dominating paradigm for statistical…

Machine Learning · Statistics 2018-11-02 Bayan Saparbayeva , Michael Minyi Zhang , Lizhen Lin

Functional connectivity refers to the temporal statistical relationship between spatially distinct brain regions and is usually inferred from the time series coherence/correlation in brain activity between regions of interest. In human…

Machine Learning · Statistics 2015-03-02 Shaurabh Nandy , Richard M. Golden

In this study we adopt predictive modelling to identify simultaneously commonalities and differences in multi-modal brain networks acquired within subjects. Typically, predictive modelling of functional connectomes from structural…

Neurons and Cognition · Quantitative Biology 2019-11-06 Fani Deligianni , Jonathan D. Clayden , Guang-Zhong Yang

Recent developments in high throughput profiling of individual neurons have spurred data driven exploration of the idea that there exist natural groupings of neurons referred to as cell types. The promise of this idea is that the immense…

Neurons and Cognition · Quantitative Biology 2019-11-14 Rohan Gala , Nathan Gouwens , Zizhen Yao , Agata Budzillo , Osnat Penn , Bosiljka Tasic , Gabe Murphy , Hongkui Zeng , Uygar Sümbül

We present a novel kernel-based machine learning algorithm for identifying the low-dimensional geometry of the effective dynamics of high-dimensional multiscale stochastic systems. Recently, the authors developed a mathematical framework…

Dynamical Systems · Mathematics 2020-02-04 Andreas Bittracher , Stefan Klus , Boumediene Hamzi , Péter Koltai , Christof Schütte

Population analyses of functional connectivity have provided a rich understanding of how brain function differs across time, individual, and cognitive task. An important but challenging task in such population analyses is the identification…

Social and Information Networks · Computer Science 2020-08-19 James D. Wilson , Melanie Baybay , Rishi Sankar , Paul Stillman , Abbie M. Popa

Spectral compressed sensing involves reconstructing a spectral-sparse signal from a subset of uniformly spaced samples, with applications in radar imaging and wireless channel estimation. By fully exploiting the signal structures, this…

Optimization and Control · Mathematics 2025-11-25 Wenlong Wang , Wen Huang , Zai Yang

Motivated by the analysis of high-dimensional neuroimaging signals located over the cortical surface, we introduce a novel Principal Component Analysis technique that can handle functional data located over a two-dimensional manifold. For…

Applications · Statistics 2019-08-02 Eardi Lila , John A. D. Aston , Laura M. Sangalli

Recent developments in experimental neuroscience make it possible to simultaneously record the activity of thousands of neurons. However, the development of analysis approaches for such large-scale neural recordings have been slower than…

Neurons and Cognition · Quantitative Biology 2022-10-18 Rufus Mitchell-Heggs , Seigfred Prado , Giuseppe P. Gava , Mary Ann Go , Simon R. Schultz

Systems neuroscience relies on two complementary views of neural data, characterized by single neuron tuning curves and analysis of population activity. These two perspectives combine elegantly in neural latent variable models that…

This paper introduces an efficient multi-linear nonparametric (kernel-based) approximation framework for data regression and imputation, and its application to dynamic magnetic-resonance imaging (dMRI). Data features are assumed to reside…

Signal Processing · Electrical Eng. & Systems 2023-04-07 Duc Thien Nguyen , Konstantinos Slavakis

This paper proposes a general framework of Riemannian adaptive optimization methods. The framework encapsulates several stochastic optimization algorithms on Riemannian manifolds and incorporates the mini-batch strategy that is often used…

Optimization and Control · Mathematics 2025-02-14 Hiroyuki Sakai , Hideaki Iiduka

Manifold alignment (MA) involves a set of techniques for learning shared representations across domains, yet many traditional MA methods are incapable of performing out-of-sample extension, limiting their real-world applicability. We…

Machine Learning · Computer Science 2025-09-30 Jake S. Rhodes , Adam G. Rustad , Marshall S. Nielsen , Morgan Chase McClellan , Dallan Gardner , Dawson Hedges

This article introduces a predictor-dependent joint modeling framework for network data obtained from multiple subjects over a shared set of nodes with spatial co-ordinates and spatially correlated nodal attributes. The framework is highly…

Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder impacting social and behavioral development. Resting-state fMRI, a non-invasive tool for capturing brain connectivity patterns, aids in early ASD diagnosis and differentiation…

Machine Learning · Computer Science 2025-02-27 Ziqiao Weng , Weidong Cai , Bo Zhou