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A two-stage adaptive optimal design is an attractive option for increasing the efficiency of clinical trials. In these designs, based on interim data, the locally optimal dose is chosen for further exploration, which induces dependencies…

Methodology · Statistics 2019-05-24 Zhantao Lin , Nancy Flournoy , William F. Rosenberger

Maximum Likelihood Estimation (MLE) and Likelihood Ratio Test (LRT) are widely used methods for estimating the transition probability matrix in Markov chains and identifying significant relationships between transitions, such as equality.…

Methodology · Statistics 2024-06-04 Yining Zhou , Ming Gao , Yiting Chen , Xiaoping Shi

Model-based reinforcement learning (MBRL) is believed to have higher sample efficiency compared with model-free reinforcement learning (MFRL). However, MBRL is plagued by dynamics bottleneck dilemma. Dynamics bottleneck dilemma is the…

Machine Learning · Computer Science 2021-06-25 Xiyao Wang , Junge Zhang , Wenzhen Huang , Qiyue Yin

We consider bootstrap inference for estimators which are (asymptotically) biased. We show that, even when the bias term cannot be consistently estimated, valid inference can be obtained by proper implementations of the bootstrap.…

Selection of important covariates and to drop the unimportant ones from a high-dimensional regression model is a long standing problem and hence have received lots of attention in the last two decades. After selecting the correct model, it…

Statistics Theory · Mathematics 2019-09-17 Debraj Das , Arindam Chatterjee , S. N. Lahiri

Empirical likelihood is an attractive inferential framework that respects natural parameter boundaries, but existing approaches typically require smoothness of the functional and miscalibrate substantially when these assumptions are…

Methodology · Statistics 2026-03-31 Hongseok Namkoong

We consider the problem of quantifying uncertainty for the estimation error of the leading eigenvector from Oja's algorithm for streaming principal component analysis, where the data are generated IID from some unknown distribution. By…

Statistics Theory · Mathematics 2022-05-23 Robert Lunde , Purnamrita Sarkar , Rachel Ward

Consider a set of categorical variables $\mathcal{P}$ where at least one, denoted by $Y$, is binary. The log-linear model that describes the counts in the resulting contingency table implies a specific logistic regression model, with the…

Methodology · Statistics 2019-12-04 Wei Jing , Michail Papathomas

We consider second order explicit and implicit two-step time-discrete schemes for wave-type equations. We derive optimal order aposteriori estimates controlling the time discretization error. Our analysis, has been motivated by the need to…

Numerical Analysis · Mathematics 2017-05-17 Emmanuil H. Georgoulis , Omar Lakkis , Charalambos Makridakis , Juha M. Virtanen

Our main objective in this paper is to develop a second-order stochastic numerical method which generalizes the well-known deterministic TR-BDF2 scheme. Since most stochastic techniques used for approximating the solution of a stochastic…

Numerical Analysis · Mathematics 2026-02-12 Tomás Caraballo , Macarena Gómez-Mármol , Ignacio Roldán

Retraining a model using its own predictions together with the original, potentially noisy labels is a well-known strategy for improving the model performance. While prior works have demonstrated the benefits of specific heuristic…

Machine Learning · Computer Science 2025-05-22 Adel Javanmard , Rudrajit Das , Alessandro Epasto , Vahab Mirrokni

This paper investigates a new approach to estimate the gradient of the conditional probability given the covariates in the binary classification framework. The proposed approach consists in fitting a localized nearest-neighbor logistic…

Statistics Theory · Mathematics 2025-01-20 Touqeer Ahmad , François Portier , Gilles Stupfler

Bootstrapping is a powerful statistical resampling technique for estimating the sampling distribution of an estimator. However, its computational cost becomes prohibitive for large datasets or a high number of resamples. This paper presents…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-10-21 Di Zhang

In this paper, we propose a novel bootstrap algorithm that is more efficient than existing methods for approximating the distribution of the factor-augmented regression estimator for a rotated parameter vector. The regression is augmented…

Methodology · Statistics 2025-10-02 Peiyun Jiang , Takashi Yamagata

Building classification models that predict a binary class label on the basis of high dimensional multi-omics datasets poses several challenges, due to the typically widely differing characteristics of the data layers in terms of number of…

Methodology · Statistics 2020-08-04 Alessandra Cabassi , Denis Seyres , Mattia Frontini , Paul D. W. Kirk

We propose Posterior Bootstrap, a set of algorithms extending Weighted Likelihood Bootstrap, to properly incorporate prior information and address the problem of model misspecification in Bayesian inference. We consider two approaches to…

Methodology · Statistics 2021-04-19 Emilia Pompe

Stochastic learning to rank (LTR) is a recent branch in the LTR field that concerns the optimization of probabilistic ranking models. Their probabilistic behavior enables certain ranking qualities that are impossible with deterministic…

Machine Learning · Computer Science 2024-05-10 Jingwei Kang , Maarten de Rijke , Harrie Oosterhuis

This study presents two new algorithms for solving linear stochastic bandit problems. The proposed methods use an approach from non-parametric statistics called bootstrapping to create confidence bounds. This is achieved without making any…

Machine Learning · Statistics 2016-05-05 Nandan Sudarsanam , Balaraman Ravindran

We show that, when the double bootstrap is used to improve performance of bootstrap methods for bias correction, techniques based on using a single double-bootstrap sample for each single-bootstrap sample can be particularly effective. In…

Statistics Theory · Mathematics 2015-11-12 Jinyuan Chang , Peter Hall

We study the distribution of the maximum likelihood estimate (MLE) in high-dimensional logistic models, extending the recent results from Sur (2019) to the case where the Gaussian covariates may have an arbitrary covariance structure. We…

Statistics Theory · Mathematics 2023-01-05 Qian Zhao , Pragya Sur , Emmanuel J. Candès
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