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Accurate segmentation of retinal fluids in 3D Optical Coherence Tomography images is key for diagnosis and personalized treatment of eye diseases. While deep learning has been successful at this task, trained supervised models often fail…

Computer Vision and Pattern Recognition · Computer Science 2022-08-05 Alvaro Gomariz , Huanxiang Lu , Yun Yvonna Li , Thomas Albrecht , Andreas Maunz , Fethallah Benmansour , Alessandra M. Valcarcel , Jennifer Luu , Daniela Ferrara , Orcun Goksel

We present an unsupervised learning framework for simultaneously training single-view depth prediction and optical flow estimation models using unlabeled video sequences. Existing unsupervised methods often exploit brightness constancy and…

Computer Vision and Pattern Recognition · Computer Science 2018-09-06 Yuliang Zou , Zelun Luo , Jia-Bin Huang

Optical coherence tomography (OCT) has stimulated a wide range of medical image-based diagnosis and treatment in fields such as cardiology and ophthalmology. Such applications can be further facilitated by deep learning-based…

Medical Physics · Physics 2023-07-24 Xueshen Li , Zhenxing Dong , Hongshan Liu , Jennifer J. Kang-Mieler , Yuye Ling , Yu Gan

Reliable automated analysis of Optical Coherence Tomography (OCT) imaging is crucial for diagnosing retinal disorders but faces a critical barrier: the need for expensive, labor-intensive expert annotations. Supervised deep learning models…

Computer Vision and Pattern Recognition · Computer Science 2026-04-27 Tania Haghighi , Sina Gholami , Hamed Tabkhi , Minhaj Nur Alam

Optical coherence tomography (OCT) is a medical imaging modality that allows us to probe deeper substructures of skin. The state-of-the-art wound care prediction and monitoring methods are based on visual evaluation and focus on surface…

Image and Video Processing · Electrical Eng. & Systems 2023-06-05 Prashant Kumar , Swatantra Dhara , Ayan Gope , Jyotirmoy Chatterjee , Subhamoy Mandal

Deep reinforcement learning (DRL) has demonstrated impressive performance in various gaming simulators and real-world applications. In practice, however, a DRL agent may receive faulty observation by abrupt interferences such as black-out,…

Machine Learning · Computer Science 2022-01-26 Chao-Han Huck Yang , I-Te Danny Hung , Yi Ouyang , Pin-Yu Chen

Since the introduction of optical coherence tomography (OCT), it has been possible to study the complex 3D morphological changes of the optic nerve head (ONH) tissues that occur along with the progression of glaucoma. Although several deep…

We demonstrate that deep reinforcement learning (deep RL) provides a highly effective strategy for the control and self-tuning of optical systems. Deep RL integrates the two leading machine learning architectures of deep neural networks and…

Signal Processing · Electrical Eng. & Systems 2020-06-11 Chang Sun , Eurika Kaiser , Steven L. Brunton , J. Nathan Kutz

While agents trained by Reinforcement Learning (RL) can solve increasingly challenging tasks directly from visual observations, generalizing learned skills to novel environments remains very challenging. Extensive use of data augmentation…

Machine Learning · Computer Science 2021-12-10 Nicklas Hansen , Hao Su , Xiaolong Wang

Longitudinal imaging is capable of capturing the static ana\-to\-mi\-cal structures and the dynamic changes of the morphology resulting from aging or disease progression. Self-supervised learning allows to learn new representation from…

Image and Video Processing · Electrical Eng. & Systems 2019-10-25 Antoine Rivail , Ursula Schmidt-Erfurth , Wolf-Dieter Vogl , Sebastian M. Waldstein , Sophie Riedl , Christoph Grechenig , Zhichao Wu , Hrvoje Bogunović

Optical coherence tomography (OCT) can perform non-invasive high-resolution three-dimensional (3D) imaging and has been widely used in biomedical fields, while it is inevitably affected by coherence speckle noise which degrades OCT imaging…

Optics · Physics 2025-06-30 Renxiong Wu , Fei Zheng , Meixuan Li , Shaoyan Huang , Xin Ge , Linbo Liu , Yong Liu , Guangming Ni

Despite the revolutionary impact of AI and the development of locally trained algorithms, achieving widespread generalized learning from multi-modal data in medical AI remains a significant challenge. This gap hinders the practical…

Computer Vision and Pattern Recognition · Computer Science 2024-01-24 Fatema-E Jannat , Sina Gholami , Minhaj Nur Alam , Hamed Tabkhi

Recent research has shown that although Reinforcement Learning (RL) can benefit from expert demonstration, it usually takes considerable efforts to obtain enough demonstration. The efforts prevent training decent RL agents with expert…

Machine Learning · Computer Science 2021-07-09 Si-An Chen , Voot Tangkaratt , Hsuan-Tien Lin , Masashi Sugiyama

The treatment of age-related macular degeneration (AMD) requires continuous eye exams using optical coherence tomography (OCT). The need for treatment is determined by the presence or change of disease-specific OCT-based biomarkers.…

Image and Video Processing · Electrical Eng. & Systems 2026-03-12 Timo Kepp , Helge Sudkamp , Claus von der Burchard , Hendrik Schenke , Peter Koch , Gereon Hüttmann , Johann Roider , Mattias P. Heinrich , Heinz Handels

Retinal vessel segmentation plays a key role in computer-aided screening, diagnosis, and treatment of various cardiovascular and ophthalmic diseases. Recently, deep learning-based retinal vessel segmentation algorithms have achieved…

Image and Video Processing · Electrical Eng. & Systems 2021-08-05 Wei Feng , Lie Ju , Lin Wang , Kaimin Song , Xin Wang , Xin Zhao , Qingyi Tao , Zongyuan Ge

Humans process visual information with varying resolution (foveated visual system) and explore images by orienting through eye movements the high-resolution fovea to points of interest. The Bayesian ideal searcher (IS) that employs complete…

Computer Vision and Pattern Recognition · Computer Science 2022-02-01 Weimin Zhou , Miguel P. Eckstein

In the medical domain, acquiring large datasets poses significant challenges due to privacy concerns. Nonetheless, the development of a robust deep-learning model for retinal disease diagnosis necessitates a substantial dataset for…

Computer Vision and Pattern Recognition · Computer Science 2024-09-18 Fatema-E- Jannat , Sina Gholami , Jennifer I. Lim , Theodore Leng , Minhaj Nur Alam , Hamed Tabkhi

Eye movements, blinking and other motion during the acquisition of optical coherence tomography (OCT) can lead to artifacts, when processed to OCT angiography (OCTA) images. Affected scans emerge as high intensity (white) or missing (black)…

Image and Video Processing · Electrical Eng. & Systems 2020-01-09 Julian Hossbach , Lennart Husvogt , Martin F. Kraus , James G. Fujimoto , Andreas K. Maier

Inpainting shadowed regions cast by superficial blood vessels in retinal optical coherence tomography (OCT) images is critical for accurate and robust machine analysis and clinical diagnosis. Traditional sequence-based approaches such as…

Computer Vision and Pattern Recognition · Computer Science 2022-02-24 Yaoqi Tang , Yufan Li , Hongshan Liu , Jiaxuan Li , Peiyao Jin , Yu Gan , Yuye Ling , Yikai Su

Unsupervised learning for monocular camera motion and 3D scene understanding has gained popularity over traditional methods, relying on epipolar geometry or non-linear optimization. Notably, deep learning can overcome many issues of…

Computer Vision and Pattern Recognition · Computer Science 2022-03-15 Claudio Cimarelli , Hriday Bavle , Jose Luis Sanchez-Lopez , Holger Voos