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Purpose: Grating-based X-ray phase-contrast imaging is a promising modality increasing the soft tissue contrast in medical imaging. In this work, the signature of lung tissue in X-ray grating-based physe-contrast imaging is investigated.…

We demonstrate dark-field x-ray microtomography in a compact, laboratory-based system capable of resolving attenuation, phase, and anisotropic scattering signals with micrometer-scale resolution across centimetre-scale samples. The method…

Standard dual-energy computed tomography (CT) uses two different X-ray energies to obtain energy-dependent tissue attenuation information to allow quantitative material decomposition. The combined use of dual-energy CT and positron emission…

Medical Physics · Physics 2020-12-30 Guobao Wang

We propose a new modeling approach for scatter estimation and descattering in polyenergetic X-ray computed tomography (CT) based on fitting models to local neighborhoods of a training set. X-ray CT is widely used in medical and industrial…

Image and Video Processing · Electrical Eng. & Systems 2021-09-30 Michael T. McCann , Marc L. Klasky , Jennifer L. Schei , Saiprasad Ravishankar

X-ray radiography is the most readily available imaging modality and has a broad range of applications that spans from diagnosis to intra-operative guidance in cardiac, orthopedics, and trauma procedures. Proper interpretation of the hidden…

Computer Vision and Pattern Recognition · Computer Science 2019-04-19 Shadi Albarqouni , Javad Fotouhi , Nassir Navab

X-ray interferometry is an emerging imaging modality with a wide variety of potential clinical applications, including lung and breast imaging, as well as in non-destructive testing, such as additive manufacturing and porosimetry. A grating…

X-ray imaging, traditionally relying on attenuation contrast, struggles to differentiate materials with similar attenuation coefficients like soft tissues. X-ray phase contrast imaging (XPCI) and dark-field (DF) imaging provide enhanced…

Medical Physics · Physics 2025-06-05 Jingcheng Yuan , Mini Das

By acquiring two sets of tomographic measurements at distinct X-ray spectra, the dual-energy CT (DECT) enables quantitative material-specific imaging. However, the conventionally decomposed material basis images may encounter severe image…

Cargo imaging with Megavoltage (MV) radiography has important applications for detecting illicit materials. It enables decomposing and quantifying materials with different atomic numbers by imaging cargo at two different x-ray energies, or…

Instrumentation and Detectors · Physics 2017-10-02 Polad M. Shikhaliev

Multi-energy X-ray tomography is studied for decomposing three materials using three X-ray energies and a classical energy-integrating detector. A novel regularization term comprises inner products between the material distribution…

Suppressing bones on chest X-rays such as ribs and clavicle is often expected to improve pathologies classification. These bones can interfere with a broad range of diagnostic tasks on pulmonary disease except for musculoskeletal system.…

Computer Vision and Pattern Recognition · Computer Science 2018-11-08 Dong Yul Oh , Il Dong Yun

Purpose: The set of linear attenuation coefficients that belong to materials in the human body is commonly assumed to be spanned by two basis functions in the range of clinical x-ray energies, even though there is evidence that the…

Medical Physics · Physics 2022-08-11 Fredrik Grönberg , Mats Persson , Hans Bornefalk

Dual energy X-ray Computed Tomography (DECT) enables to automatically decompose materials in clinical images without the manual segmentation using the dependency of the X-ray linear attenuation with energy. In this work we propose a deep…

Image and Video Processing · Electrical Eng. & Systems 2024-06-04 Jiandong Wang , Alessandro Perelli

Extending our prior work, we propose a multi-energy X-ray measurement model incorporating material variability with energy correlations to enable the analysis and exploration of the performance of X-ray imaging and sensing systems. Based on…

Signal Processing · Electrical Eng. & Systems 2020-02-26 Yijun Ding , Amit Ashok

Background: Recently, the popularity of dual-layer flat-panel detector (DL-FPD) based dual-energy cone-beam CT (DE-CBCT) imaging has been increasing. However, the image quality of DE-CBCT remains constrained by the Compton scattered X-ray…

Multi-energy radiography is a new direction in non-destructive testing. Its specific feature is separate detection of penetrating radiation in several energy channels. Multi-energy radiography allows quantitative determination of the atomic…

Instrumentation and Detectors · Physics 2009-11-11 Sergei V. Naydenov , Vladimir D. Ryzhikov , Craig F. Smith , Dennis Wood

Dual-energy computed tomography (DECT) has been widely used to obtain quantitative elemental composition of imaged subjects for personalized and precise medical diagnosis. Compared with DECT leveraging advanced X-ray source and/or detector…

Medical Physics · Physics 2024-08-28 Qiaoxin Li , Ruifeng Chen , Peng Wang , Guotao Quan , Yanfeng Du , Dong Liang , Yinsheng Li

Varian Medical Systems has manufactured and recently put into operation a clinically-applicable solution for image-guided radiation therapy. Cone-beam CT imaging, one of the operation modes of the imaging unit of this device, aims at…

Medical Physics · Physics 2007-05-23 Evangelos Matsinos , Wolfgang Kaissl

Spectral CT has great potential for a variety of clinical applications due to the improved material discrimination with respect to conventional CT. Many clinical and preclinical spectral CT systems have two spectral channels for dual-energy…

Medical Physics · Physics 2020-10-17 Matthew Tivnan , Wenying Wang , J. Webster Stayman

Purpose: Electron density is the most important tissue property influencing photon and ion dose distributions in radiotherapy patients. Dual-energy computed tomography (DECT) enables the determination of electron density by combining the…

Medical Physics · Physics 2017-06-29 Christian Möhler , Patrick Wohlfahrt , Christian Richter , Steffen Greilich