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Cancers are the leading cause of death in many countries. Early diagnosis plays a crucial role in having proper treatment for this debilitating disease. The automated classification of the type of cancer is a challenging task since…

Image and Video Processing · Electrical Eng. & Systems 2021-08-20 Hosein Barzekar , Zeyun Yu

We present HistoAtlas, a pan-cancer computational atlas that extracts 38 interpretable histomic features from 6,745 diagnostic H&E slides across 21 TCGA cancer types and systematically links every feature to survival, gene expression,…

Quantitative Methods · Quantitative Biology 2026-03-18 Pierre-Antoine Bannier

In computation pathology, the pyramid structure of gigapixel Whole Slide Images (WSIs) has recently been studied for capturing various information from individual cell interactions to tissue microenvironments. This hierarchical structure is…

Computer Vision and Pattern Recognition · Computer Science 2023-09-15 Ziyu Guo , Weiqin Zhao , Shujun Wang , Lequan Yu

Bone marrow cytology is required to make a hematological diagnosis, influencing critical clinical decision points in hematology. However, bone marrow cytology is tedious, limited to experienced reference centers and associated with high…

Image and Video Processing · Electrical Eng. & Systems 2021-07-09 Rohollah Moosavi Tayebi , Youqing Mu , Taher Dehkharghanian , Catherine Ross , Monalisa Sur , Ronan Foley , Hamid R. Tizhoosh , Clinton JV Campbell

While challenging, the dense segmentation of histology images is a necessary first step to assess changes in tissue architecture and cellular morphology. Although specific convolutional neural network architectures have been applied with…

Computer Vision and Pattern Recognition · Computer Science 2018-06-13 Korsuk Sirinukunwattana , Nasullah Khalid Alham , Clare Verrill , Jens Rittscher

This study introduces a novel and accurate approach to breast cancer classification using histopathology images. It systematically compares leading Convolutional Neural Network (CNN) models across varying image datasets, identifies their…

Computer Vision and Pattern Recognition · Computer Science 2024-10-07 Gary Murphy , Raghubir Singh

Breast cancer is a relatively common cancer among gynecological cancers. Its diagnosis often relies on the pathology of cells in the lesion. The pathological diagnosis of breast cancer not only requires professionals and time, but also…

Image and Video Processing · Electrical Eng. & Systems 2024-04-15 MingXuan Xiao , Yufeng Li , Xu Yan , Min Gao , Weimin Wang

Purpose: Accurate identification of hepatocystic anatomy is critical to preventing surgical complications during laparoscopic cholecystectomy. Deep learning models often struggle with occlusions, long-range dependencies, and capturing the…

Computer Vision and Pattern Recognition · Computer Science 2025-11-21 Yihan Li , Nikhil Churamani , Maria Robu , Imanol Luengo , Danail Stoyanov

The spectacular response observed in clinical trials of immunotherapy in patients with previously uncurable Melanoma, a highly aggressive form of skin cancer, calls for a better understanding of the cancer-immune interface. Computational…

Computer Vision and Pattern Recognition · Computer Science 2018-08-08 Konstantinos Zormpas-Petridis , Henrik Failmezger , Ioannis Roxanis , Matthew Blackledge , Yann Jamin , Yinyin Yuan

Tumour heterogeneity in breast cancer poses challenges in predicting outcome and response to therapy. Spatial transcriptomics technologies may address these challenges, as they provide a wealth of information about gene expression at the…

Image and Video Processing · Electrical Eng. & Systems 2023-09-19 Md Mamunur Rahaman , Ewan K. A. Millar , Erik Meijering

Deep neural networks have introduced significant advancements in the field of machine learning-based analysis of digital pathology images including prostate tissue images. With the help of transfer learning, classification and segmentation…

Deep learning based analysis of histopathology images shows promise in advancing the understanding of tumor progression, tumor micro-environment, and their underpinning biological processes. So far, these approaches have focused on…

Image and Video Processing · Electrical Eng. & Systems 2021-08-29 Adalberto Claudio Quiros , Nicolas Coudray , Anna Yeaton , Wisuwat Sunhem , Roderick Murray-Smith , Aristotelis Tsirigos , Ke Yuan

Positron emission tomography (PET) combined with computed tomography (CT) imaging is routinely used in cancer diagnosis and prognosis by providing complementary information. Automatically segmenting tumors in PET/CT images can significantly…

Image and Video Processing · Electrical Eng. & Systems 2024-03-29 Jinpeng Lu , Jingyun Chen , Linghan Cai , Songhan Jiang , Yongbing Zhang

Digital histology images are amenable to the application of convolutional neural network (CNN) for analysis due to the sheer size of pixel data present in them. CNNs are generally used for representation learning from small image patches…

Image and Video Processing · Electrical Eng. & Systems 2019-07-24 Muhammad Shaban , Ruqayya Awan , Muhammad Moazam Fraz , Ayesha Azam , David Snead , Nasir M. Rajpoot

Network biology has been successfully used to help reveal complex mechanisms of disease, especially cancer. On the other hand, network biology requires in-depth knowledge to construct disease-specific networks, but our current knowledge is…

Computer Vision and Pattern Recognition · Computer Science 2018-06-18 Sungmin Rhee , Seokjun Seo , Sun Kim

Breast cancer is a leading cause of cancer-related mortality worldwide, and timely accurate diagnosis is critical to improving survival outcomes. While convolutional neural networks (CNNs) have demonstrated strong performance on…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Aditya Shribhagwan Khandelwal , Mohammad Samar Ansari , Asra Aslam

Dealing with the application of grading colorectal cancer images, this work proposes a 3 step pipeline for prediction of cancer levels from a histopathology image. The overall model performs better compared to other state of the art methods…

Computer Vision and Pattern Recognition · Computer Science 2020-10-05 Franziska Lippoldt

Breast cancer is one of the most common cancers in women worldwide, and early detection can significantly reduce the mortality rate of breast cancer. It is crucial to take multi-scale information of tissue structure into account in the…

Computer Vision and Pattern Recognition · Computer Science 2021-01-01 Mo Zhang , Quanzheng Li

Breast cancer is one of the leading causes of death across the world in women. Early diagnosis of this type of cancer is critical for treatment and patient care. Computer-aided detection (CAD) systems using convolutional neural networks…

Image and Video Processing · Electrical Eng. & Systems 2019-09-27 Sara Hosseinzadeh Kassani , Peyman Hosseinzadeh Kassani , Michal J. Wesolowski , Kevin A. Schneider , Ralph Deters

Histopathological images are widely used for the analysis of diseased (tumor) tissues and patient treatment selection. While the majority of microscopy image processing was previously done manually by pathologists, recent advances in…

Image and Video Processing · Electrical Eng. & Systems 2024-07-12 Andrey Ignatov , Josephine Yates , Valentina Boeva