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Protein contacts provide key information for the understanding of protein structure and function, and therefore contact prediction from sequences is an important problem. Recent research shows that some correctly predicted long-range…

Quantitative Methods · Quantitative Biology 2020-09-02 Siqi Sun

The reproduction and replication of research results has become a major issue for a number of scientific disciplines. In computer science and related computational disciplines such as systems biology, the challenges closely revolve around…

Software Engineering · Computer Science 2017-07-31 Tom Crick , Benjamin A. Hall , Samin Ishtiaq

The breakthrough in Deep Learning neural networks has transformed the use of AI and machine learning technologies for the analysis of very large experimental datasets. These datasets are typically generated by large-scale experimental…

Machine Learning · Computer Science 2021-10-26 Jeyan Thiyagalingam , Mallikarjun Shankar , Geoffrey Fox , Tony Hey

Commonsense question-answering (QA) tasks, in the form of benchmarks, are constantly being introduced for challenging and comparing commonsense QA systems. The benchmarks provide question sets that systems' developers can use to train and…

Artificial Intelligence · Computer Science 2020-12-23 Henrique Santos , Minor Gordon , Zhicheng Liang , Gretchen Forbush , Deborah L. McGuinness

Achieving fault-tolerance will require a strong relationship between the hardware and the protocols used. Different approaches will therefore naturally have tailored proof-of-principle experiments to benchmark progress. Nevertheless,…

Quantum Physics · Physics 2024-05-28 Milan Liepelt , Tommaso Peduzzi , James R. Wootton

Proteins are central to biological systems, participating as building blocks across all forms of life. Despite advancements in understanding protein functions through protein sequence analysis, there remains potential for further…

Machine Learning · Computer Science 2025-08-29 Yunqing Liu , Wenqi Fan , Xiaoyong Wei , Qing Li

Proteins play a pivotal role in biological systems. The use of machine learning algorithms for protein classification can assist and even guide biological experiments, offering crucial insights for biotechnological applications. We…

Quantitative Methods · Quantitative Biology 2024-10-24 Yizheng Wang , Yixiao Zhai , Yijie Ding , Quan Zou

Identification of communities in complex networks has become an effective means to analysis of complex systems. It has broad applications in diverse areas such as social science, engineering, biology and medicine. Finding communities of…

Social and Information Networks · Computer Science 2013-09-19 Dongxiao He , Di Jin , Weixiong Zhang

Cancer is a number of related yet highly heterogeneous diseases. Correct identification of cancer subtypes is critical for clinical decisions. The advance in sequencing technologies has made it possible to study cancer based on abundant…

Applications · Statistics 2018-11-27 Xiaochun Chen , Honggang Wang , Donghui Yan

Numerous cellular functions rely on protein$\unicode{x2013}$protein interactions. Efforts to comprehensively characterize them remain challenged however by the diversity of molecular recognition mechanisms employed within the proteome. Deep…

Biomolecules · Quantitative Biology 2023-12-08 Julia R. Rogers , Gergő Nikolényi , Mohammed AlQuraishi

Link prediction problem has increasingly become prominent in many domains such as social network analyses, bioinformatics experiments, transportation networks, criminal investigations and so forth. A variety of techniques has been developed…

Artificial Intelligence · Computer Science 2023-05-18 Safiye Ghasemi , Amin Zarei

Spectrum sensing and analysis is crucial for a variety of reasons, including regulatory compliance, interference detection and mitigation, and spectrum resource planning and optimization. Effective, real-time spectrum analysis remains a…

Signal Processing · Electrical Eng. & Systems 2026-01-21 Rahil Gandotra , Ruoyu Sun , Mark Poletti , Jiayu Mao , Hao Guo

The detection of overlapping communities is a challenging problem which is gaining increasing interest in recent years because of the natural attitude of individuals, observed in real-world networks, to participate in multiple groups at the…

Social and Information Networks · Computer Science 2014-11-17 Alessia Amelio , Clara Pizzuti

Human physiology and pathology arise from the coordinated interactions of diverse single cells. However, analyzing single cells has been limited by the low sensitivity and throughput of analytical methods. DNA sequencing has recently made…

Quantitative Methods · Quantitative Biology 2020-06-23 Nikolai Slavov

Clustering methods are applied regularly in the bibliometric literature to identify research areas or scientific fields. These methods are for instance used to group publications into clusters based on their relations in a citation network.…

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Feature matching is an important technique to identify a single object in different images. It helps machines to construct recognition of a specific object from multiple perspectives. For years, feature matching has been commonly used in…

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Feature matching is one of the most fundamental and active research areas in computer vision. A comprehensive evaluation of feature matchers is necessary, since it would advance both the development of this field and also high-level…

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With the advancement of high-throughput biotechnologies, we increasingly accumulate biomedical data about diseases, especially cancer. There is a need for computational models and methods to sift through, integrate, and extract new…

Quantitative Methods · Quantitative Biology 2020-07-03 Thomas Gaudelet , Noel Malod-Dognin , Natasa Przulj

Despite recent development in methodology, community detection remains a challenging problem. Existing literature largely focuses on the standard setting where a network is learned using an observed adjacency matrix from a single data…

Methodology · Statistics 2018-06-21 Luwan Zhang , Katherine Liao , Issac Kohane , Tianxi Cai

Background: The inception of next generations sequencing technologies have exponentially increased the volume of biological sequence data. Protein sequences, being quoted as the `language of life', has been analyzed for a multitude of…

Quantitative Methods · Quantitative Biology 2020-12-08 Nabil Ibtehaz , S. M. Shakhawat Hossain Sourav , Md. Shamsuzzoha Bayzid , M. Sohel Rahman