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Current Computer-Aided Diagnosis (CAD) methods mainly depend on medical images. The clinical information, which usually needs to be considered in practical clinical diagnosis, has not been fully employed in CAD. In this paper, we propose a…

Image and Video Processing · Electrical Eng. & Systems 2021-03-11 Songxiao Yang , Xiabi Liu , Zhongshu Zheng , Wei Wang , Xiaohong Ma

We consider a problem of diagnostic pattern recognition/classification from neuroimaging data. We propose a common data analysis pipeline for neuroimaging-based diagnostic classification problems using various ML algorithms and processing…

Computer Vision and Pattern Recognition · Computer Science 2018-04-27 Alexander Bernstein , Evgeny Burnaev , Ekaterina Kondratyeva , Svetlana Sushchinskaya , Maxim Sharaev , Alexander Andreev , Alexey Artemov , Renat Akzhigitov

While the prevalence of Autism Spectrum Disorder (ASD) is increasing, research continues in an effort to identify common etiological and pathophysiological bases. In this regard, modern machine learning and network science pave the way for…

Image and Video Processing · Electrical Eng. & Systems 2020-08-06 Sarah Itani , Dorina Thanou

Large, open-source consortium datasets have spurred the development of new and increasingly powerful machine learning approaches in brain connectomics. However, one key question remains: are we capturing biologically relevant and…

Functional connectivity, as estimated using resting state fMRI, has shown potential in bridging the gap between pathophysiology and cognition. However, clinical use of functional connectivity biomarkers is impeded by unreliable estimates of…

For automated assessment of knee MRI scans, both accuracy and interpretability are essential for clinical use and adoption. Traditional radiomics rely on predefined features chosen at the population level; while more interpretable, they are…

Computer Vision and Pattern Recognition · Computer Science 2026-01-14 Yaxi Chen , Simin Ni , Shuai Li , Shaheer U. Saeed , Aleksandra Ivanova , Rikin Hargunani , Jie Huang , Chaozong Liu , Yipeng Hu

This study presents an integrated approach for advancing functional Near-Infrared Spectroscopy (fNIRS) neuroimaging through the synthesis of data and application of machine learning models. By addressing the scarcity of high-quality…

Signal Processing · Electrical Eng. & Systems 2024-05-21 Eitan Waks

As machine learning and artificial intelligence are more frequently being leveraged to tackle problems in the health sector, there has been increased interest in utilizing them in clinical decision-support. This has historically been the…

Machine Learning · Computer Science 2022-04-12 Adrienne Kline , Hanyin Wang , Yikuan Li , Saya Dennis , Meghan Hutch , Zhenxing Xu , Fei Wang , Feixiong Cheng , Yuan Luo

The development of diagnostic models is gaining traction in the field of psychiatric disorders. Recently, machine learning classifiers based on resting-state functional magnetic resonance imaging (rs-fMRI) have been developed to identify…

Machine Learning · Computer Science 2025-10-06 Tianzheng Hu , Qiang Li , Shu Liu , Vince D. Calhoun , Guido van Wingen , Shujian Yu

The estimation of sparse hierarchical components reflecting patterns of the brain's functional connectivity from rsfMRI data can contribute to our understanding of the brain's functional organization, and can lead to biomarkers of diseases.…

Machine Learning · Computer Science 2021-04-22 Dushyant Sahoo , Christos Davatzikos

Recently, Big Data applications have rapidly expanded into different industries. Healthcare is also one the industries willing to use big data platforms so that some big data analytics tools have been adopted in this field to some extent.…

Distributed, Parallel, and Cluster Computing · Computer Science 2016-03-24 Saman Sarraf , Mehdi Ostadhashem

There has been much progress in data-driven artificial intelligence technology for medical image analysis in the last decades. However, it still remains challenging due to its distinctive complexity of acquiring and annotating image data,…

Computer Vision and Pattern Recognition · Computer Science 2021-06-30 Chao Gou , Tianyu Shen , Wenbo Zheng , Huadan Xue , Hui Yu , Qiang Ji , Zhengyu Jin , Fei-Yue Wang

Mental health disorders are rising worldwide. However, the availability of trained clinicians has not scaled proportionally, leaving many people without adequate or timely support. To bridge this gap, recent studies have shown the promise…

Computation and Language · Computer Science 2025-08-19 Aishik Mandal , Prottay Kumar Adhikary , Hiba Arnaout , Iryna Gurevych , Tanmoy Chakraborty

We propose a novel deep neural network architecture to integrate imaging and genetics data, as guided by diagnosis, that provides interpretable biomarkers. Our model consists of an encoder, a decoder and a classifier. The encoder learns a…

Many fMRI analyses examine functional connectivity, or statistical dependencies among remote brain regions. Yet popular methods for studying whole-brain functional connectivity often yield results that are difficult to interpret. Factor…

Methodology · Statistics 2024-09-24 Kyle Stanley , Nicole Lazar , Matthew Reimherr

Data-driven approaches for depression diagnosis have emerged as a significant research focus in neuromedicine, driven by the development of relevant datasets. Recently, graph neural network (GNN)-based models have gained widespread adoption…

Machine Learning · Computer Science 2025-05-01 Chengkai Yang , Xingping Dong , Xiaofen Zong

Functional magnetic resonance imaging (fMRI) has provided invaluable insight into our understanding of human behavior. However, large inter-individual differences in both brain anatomy and functional localization after anatomical alignment…

Applications · Statistics 2021-11-03 Guoqing Wang , Abhirup Datta , Martin A. Lindquist

The increasing digitization of medical imaging enables machine learning based improvements in detecting, visualizing and segmenting lesions, easing the workload for medical experts. However, supervised machine learning requires reliable…

Image and Video Processing · Electrical Eng. & Systems 2024-12-03 Maximilian E. Tschuchnig , Michael Gadermayr

Purpose: Functional Magnetic Resonance Imaging (fMRI) data acquired through resting-state studies have been used to obtain information about the spontaneous activations inside the brain. One of the approaches for analysis and interpretation…

Image and Video Processing · Electrical Eng. & Systems 2022-02-24 Harshit Parmar , Brian Nutter , Rodney Long , Sameer Antani , Sunanda Mitra

Functional magnetic resonance imaging (fMRI) data is characterized by its complexity and high--dimensionality, encompassing signals from various regions of interests (ROIs) that exhibit intricate correlations. Analyzing fMRI data directly…

Applications · Statistics 2024-01-18 Yeseul Jeon , Jeong-Jae Kim , SuMin Yu , Junggu Choi , Sanghoon Han