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Traditional reconstruction-based methods have struggled to achieve competitive performance in anomaly detection. In this paper, we introduce Denoising Diffusion Anomaly Detection (DDAD), a novel denoising process for image reconstruction…
Prostate cancer is a commonly diagnosed cancerous disease among men world-wide. Even with modern technology such as multi-parametric magnetic resonance tomography and guided biopsies, the process for diagnosing prostate cancer remains time…
PURPOSE: Deep learning methods for classifying prostate cancer (PCa) in ultrasound images typically employ convolutional networks (CNNs) to detect cancer in small regions of interest (ROI) along a needle trace region. However, this approach…
Many interesting tasks in image restoration can be cast as linear inverse problems. A recent family of approaches for solving these problems uses stochastic algorithms that sample from the posterior distribution of natural images given the…
Fluorescence microscopy plays an important role in biomedical research. The depth-variant point spread function (PSF) of a fluorescence microscope produces low-quality images especially in the out-of-focus regions of thick specimens.…
Despite the advances in medicine, cancer has remained a formidable challenge. Particularly in the case of pancreatic tumors, characterized by their diversity and late diagnosis, early detection poses a significant challenge crucial for…
Due to the potential risk of inducing cancers, radiation dose of X-ray CT should be reduced for routine patient scanning. However, in low-dose X-ray CT, severe artifacts usually occur due to photon starvation, beamhardening, etc, which…
Denoising low-dose computed tomography (CT) images is a critical task in medical image computing. Supervised deep learning-based approaches have made significant advancements in this area in recent years. However, these methods typically…
As PET imaging is accompanied by substantial radiation exposure and cancer risk, reducing radiation dose in PET scans is an important topic. However, low-count PET scans often suffer from high image noise, which can negatively impact image…
Current deep learning approaches for diffusion MRI modeling circumvent the need for densely-sampled diffusion-weighted images (DWIs) by directly predicting microstructural indices from sparsely-sampled DWIs. However, they implicitly make…
Denoising diffusion models (DDM) have gained recent traction in medical image translation given improved training stability over adversarial models. DDMs learn a multi-step denoising transformation to progressively map random Gaussian-noise…
Most of the existing denoising algorithms are developed for grayscale images, while it is not a trivial work to extend them for color image denoising because the noise statistics in R, G, B channels can be very different for real noisy…
Recent advancements in diffusion models have demonstrated significant success in unsupervised anomaly segmentation. For anomaly segmentation, these models are first trained on normal data; then, an anomalous image is noised to an…
The challenge of image generation has been effectively modeled as a problem of structure priors or transformation. However, existing models have unsatisfactory performance in understanding the global input image structures because of…
Diffusion MRI (dMRI) enables non-invasive assessment of prostate microstructure but conventional dMRI metrics such as the Apparent Diffusion Coefficient in multiparametric MRI and reflect a mixture of underlying tissues features rather than…
Medical image segmentation using deep neural networks has been highly successful. However, the effectiveness of these networks is often limited by inadequate dense prediction and inability to extract robust features. To achieve refined…
Recent years have witnessed the great success of deep convolutional neural networks (CNNs) in image denoising. Albeit deeper network and larger model capacity generally benefit performance, it remains a challenging practical issue to train…
Deep convolutional networks often append additive constant ("bias") terms to their convolution operations, enabling a richer repertoire of functional mappings. Biases are also used to facilitate training, by subtracting mean response over…
Image denoising is an important problem in low-level vision and serves as a critical module for many image recovery tasks. Anisotropic diffusion is a wide family of image denoising approaches with promising performance. However, traditional…
Protoacoustic imaging showed great promise in providing real-time 3D dose verification of proton therapy. However, the limited acquisition angle in protoacoustic imaging induces severe artifacts, which significantly impairs its accuracy for…