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In this paper, we propose a method for denoising diffusion-weighted images (DWI) of the brain using a convolutional neural network trained on realistic, synthetic MR data. We compare our results to averaging of repeated scans, a widespread…

Image and Video Processing · Electrical Eng. & Systems 2022-06-02 Jakub Jurek , Andrzej Materka , Kamil Ludwisiak , Agata Majos , Kamil Gorczewski , Kamil Cepuch , Agata Zawadzka

Data from a multi-parametric MRI study of patients with possible early-stage prostate cancer was assessed with a view to creating an efficient clinical protocol. Based on a correlation analysis suggesting that diffusion-weighted imaging…

Medical Physics · Physics 2017-11-28 Ioannis Papadopoulos , Jonathan Phillips , Rhodri Evans , Neil Fenn , Sophie Schermer

The noise in diffusion-weighted images (DWIs) decreases the accuracy and precision of diffusion tensor magnetic resonance imaging (DTI) derived microstructural parameters and leads to prolonged acquisition time for achieving improved…

Image and Video Processing · Electrical Eng. & Systems 2021-11-16 Qiyuan Tian , Ziyu Li , Qiuyun Fan , Jonathan R. Polimeni , Berkin Bilgic , David H. Salat , Susie Y. Huang

Data augmentation refers to a group of techniques whose goal is to battle limited amount of available data to improve model generalization and push sample distribution toward the true distribution. While different augmentation strategies…

Quantitative Methods · Quantitative Biology 2020-06-03 Ruqian Hao , Khashayar Namdar , Lin Liu , Masoom A. Haider , Farzad Khalvati

In Canada, prostate cancer is the most common form of cancer in men and accounted for 20% of new cancer cases for this demographic in 2022. Due to recent successes in leveraging machine learning for clinical decision support, there has been…

Image and Video Processing · Electrical Eng. & Systems 2023-12-01 Aditya Sridhar , Chi-en Amy Tai , Hayden Gunraj , Yuhao Chen , Alexander Wong

Our hypothesis is that UDA using diffusion-weighted images, generated with a unified model, offers a promising and reliable strategy for enhancing the performance of supervised learning models in multi-site prostate lesion detection,…

Purpose: To accelerate radially sampled diffusion weighted spin-echo (Rad-DW-SE) acquisition method for generating high quality apparent diffusion coefficient (ADC) maps. Methods: A deep learning method was developed to generate accurate…

Image and Video Processing · Electrical Eng. & Systems 2023-08-15 Yuemeng Li , Miguel Romanello Joaquim , Stephen Pickup , Hee Kwon Song , Rong Zhou , Yong Fan

Diffusion MRI (dMRI) is essential for studying brain microstructure, but high-resolution imaging remains challenging due to the inherent trade-offs between acquisition time and signal-to-noise ratio (SNR). Conventional methods often…

Image and Video Processing · Electrical Eng. & Systems 2025-05-20 Yinzhe Wu , Jiahao Huang , Fanwen Wang , Mengze Gao , Congyu Liao , Guang Yang , Kawin Setsompop

Prostate cancer is one of the most common forms of cancer and the third leading cause of cancer death in North America. As an integrated part of computer-aided detection (CAD) tools, diffusion-weighted magnetic resonance imaging (DWI) has…

Computer Vision and Pattern Recognition · Computer Science 2020-06-11 Sunghwan Yoo , Isha Gujrathi , Masoom A. Haider , Farzad Khalvati

Diffusion tensor imaging (DTI) holds significant importance in clinical diagnosis and neuroscience research. However, conventional model-based fitting methods often suffer from sensitivity to noise, leading to decreased accuracy in…

Computer Vision and Pattern Recognition · Computer Science 2024-09-05 Jialong Li , Zhicheng Zhang , Yunwei Chen , Qiqi Lu , Ye Wu , Xiaoming Liu , QianJin Feng , Yanqiu Feng , Xinyuan Zhang

End-to-end deep learning improves breast cancer classification on diffusion-weighted MR images (DWI) using a convolutional neural network (CNN) architecture. A limitation of CNN as opposed to previous model-based approaches is the…

We present Distortion-Guided Restoration (DGR), a physics-informed hybrid CNN-diffusion framework for acquisition-free correction of severe susceptibility-induced distortions in prostate single-shot EPI diffusion-weighted imaging (DWI). DGR…

Image and Video Processing · Electrical Eng. & Systems 2026-04-02 Ziyang Long , Binesh Nader , Lixia Wang , Archana Vadiraj Malaji , Chia-Chi Yang , Haoran Sun , Rola Saouaf , Timothy Daskivich , Hyung Kim , Yibin Xie , Debiao Li , Hsin-Jung Yang

The segmentation of prostate whole gland and transition zone in Diffusion Weighted MRI (DWI) are the first step in designing computer-aided detection algorithms for prostate cancer. However, variations in MRI acquisition parameters and…

Image and Video Processing · Electrical Eng. & Systems 2020-10-29 Saman Motamed , Isha Gujrathi , Dominik Deniffel , Anton Oentoro , Masoom A. Haider , Farzad Khalvati

Magnetic resonance imaging technique known as DWI (diffusion-weighted imaging) allows measurement of water diffusivity on a pixel basis for evaluating pathology throughout the body and is now routinely incorporated into many body MRI…

Medical Physics · Physics 2016-11-28 Andrea Barucci , Roberto Carpi , Marco Esposito , Maristella Olmastroni , Giovanna Zatelli

Convolutional neural network (CNN)-based image denoising methods have been widely studied recently, because of their high-speed processing capability and good visual quality. However, most of the existing CNN-based denoisers learn the image…

Image and Video Processing · Electrical Eng. & Systems 2020-06-30 Rui Zhao , Kin-Man Lam , Daniel P. K. Lun

Current deep learning approaches for prostate cancer lesion segmentation achieve limited performance, with Dice scores of 0.32 or lower in large patient cohorts. To address this limitation, we investigate synthetic correlated diffusion…

Computer Vision and Pattern Recognition · Computer Science 2025-11-12 Jarett Dewbury , Chi-en Amy Tai , Alexander Wong

We propose a novel approach to denoising diffusion magnetic resonance images (dMRI) using convolutional neural networks, that exploits the benefits of data acquired at multiple b-values to offset the need for many redundant observations.…

Image and Video Processing · Electrical Eng. & Systems 2024-10-23 Jakub Jurek , Andrzej Materka , Kamil Ludwisiak , Agata Majos , Filip Szczepankiewicz

Diffusion magnetic resonance imaging (dMRI) plays a vital role in both clinical diagnostics and neuroscience research. However, its inherently low signal-to-noise ratio (SNR), especially under high diffusion weighting, significantly…

Quantitative Methods · Quantitative Biology 2026-02-27 Jine Xie , Zhicheng Zhang , Yunwei Chen , Yanqiu Feng , Xinyuan Zhang

Diffusion weighted magnetic resonance imaging (DW-MR) is a powerful tool in imaging-based prostate cancer screening and detection. Endorectal coils are commonly used in DW-MR imaging to improve the signal-to-noise ratio (SNR) of the…

The prevalent convolutional neural network (CNN) based image denoising methods extract features of images to restore the clean ground truth, achieving high denoising accuracy. However, these methods may ignore the underlying distribution of…

Computer Vision and Pattern Recognition · Computer Science 2021-05-12 Yang Liu , Saeed Anwar , Zhenyue Qin , Pan Ji , Sabrina Caldwell , Tom Gedeon
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