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Computational modeling helps neuroscientists to integrate and explain experimental data obtained through neurophysiological and anatomical studies, thus providing a mechanism by which we can better understand and predict the principles of…

Neurons and Cognition · Quantitative Biology 2023-09-22 Parvin Zarei Eskikand , David B Grayden , Tatiana Kameneva , Anthony N Burkitt , Michael R Ibbotson

While the prevalence of Autism Spectrum Disorder (ASD) is increasing, research continues in an effort to identify common etiological and pathophysiological bases. In this regard, modern machine learning and network science pave the way for…

Image and Video Processing · Electrical Eng. & Systems 2020-08-06 Sarah Itani , Dorina Thanou

With fast advancements in technologies, the collection of multiple types of measurements on a common set of subjects is becoming routine in science. Some notable examples include multimodal neuroimaging studies for the simultaneous…

Methodology · Statistics 2019-08-30 Yi Zhao , Lexin Li , Brian S. Caffo

Recent advances in network science, applied to \textit{in vivo} brain recordings, have paved the way for better understanding of the structure and function of the brain. However, despite its obvious usefulness in neuroscience, traditional…

Neurons and Cognition · Quantitative Biology 2025-02-03 Vesna Vuksanovic

Neural computation in biological and artificial networks relies on the nonlinear summation of many inputs. The structural connectivity matrix of synaptic weights between neurons is a critical determinant of overall network function, but…

Neurons and Cognition · Quantitative Biology 2022-07-01 Tirthabir Biswas , James E. Fitzgerald

A main challenge of data-driven sciences is how to make maximal use of the progressively expanding databases of experimental datasets in order to keep research cumulative. We introduce the idea of a modeling-based dataset retrieval engine…

Quantitative Methods · Quantitative Biology 2015-06-19 Ali Faisal , Jaakko Peltonen , Elisabeth Georgii , Johan Rung , Samuel Kaski

We introduce deep neural networks for the analysis of anatomical shapes that learn a low-dimensional shape representation from the given task, instead of relying on hand-engineered representations. Our framework is modular and consists of…

Computer Vision and Pattern Recognition · Computer Science 2020-10-05 Benjamin Gutierrez Becker , Ignacio Sarasua , Christian Wachinger

An established normative approach for understanding the algorithmic basis of neural computation is to derive online algorithms from principled computational objectives and evaluate their compatibility with anatomical and physiological…

Neurons and Cognition · Quantitative Biology 2023-08-04 David Lipshutz , Yanis Bahroun , Siavash Golkar , Anirvan M. Sengupta , Dmitri B. Chklovskii

Understanding the complexity of biological neural networks like the human brain is one of the scientific challenges of our century. The organization of the brain can be described at different levels, ranging from small neural networks to…

Neurons and Cognition · Quantitative Biology 2018-05-23 Stefano De Blasi

A substantial amount of time and energy has been invested to develop machine vision using connectionist (neural network) principles. Most of that work has been inspired by theories advanced by neuroscientists and behaviorists for how…

Neurons and Cognition · Quantitative Biology 2020-09-01 Ernest Greene

Understanding the mechanisms of neural communication in large-scale brain networks remains a major goal in neuroscience. We investigated whether navigation is a parsimonious routing model for connectomics. Navigating a network involves…

Neurons and Cognition · Quantitative Biology 2018-06-05 Caio Seguin , Martijn P. van den Heuvel , Andrew Zalesky

Laboratory-grown, engineered living neuronal networks in vitro have emerged in the last years as an experimental technique to understand the collective behavior of neuronal assemblies in relation to their underlying connectivity. An…

Neurons and Cognition · Quantitative Biology 2025-01-09 Akke Mats Houben , Jordi Garcia-Ojalvo , Jordi Soriano

Understanding the relation between cortical neuronal network structure and neuronal activity is a fundamental unresolved question in neuroscience, with implications to our understanding of the mechanism by which neuronal networks evolve…

Integrating brain imaging data with clinical reports offers a valuable opportunity to leverage complementary multimodal information for more effective and timely diagnosis in practical clinical settings. This approach has gained significant…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Jing Zhang , Xiaowei Yu , Minheng Chen , Lu Zhang , Tong Chen , Yan Zhuang , Chao Cao , Yanjun Lyu , Li Su , Tianming Liu , Dajiang Zhu

Neuroscience is undergoing faster changes than ever before. Over 100 years our field qualitatively described and invasively manipulated single or few organisms to gain anatomical, physiological, and pharmacological insights. In the last 10…

Neurons and Cognition · Quantitative Biology 2016-08-12 Danilo Bzdok , B. T. Thomas Yeo

Seeking effective neural networks is a critical and practical field in deep learning. Besides designing the depth, type of convolution, normalization, and nonlinearities, the topological connectivity of neural networks is also important.…

Computer Vision and Pattern Recognition · Computer Science 2020-08-20 Kun Yuan , Quanquan Li , Jing Shao , Junjie Yan

Understanding the evolution of brain functional networks over time is of great significance for the analysis of cognitive mechanisms and the diagnosis of neurological diseases. Existing methods often have difficulty in capturing the…

Machine Learning · Computer Science 2025-10-30 Tianqi Guo , Liping Chen , Ciyuan Peng , Jingjing Zhou , Jing Ren

Understanding the deep representations of complex networks is an important step of building interpretable and trustworthy machine learning applications in the age of internet. Global surrogate models that approximate the predictions of a…

Machine Learning · Computer Science 2022-03-15 Baihan Lin

Network models are widely used to represent relational information among interacting units and the structural implications of these relations. Recently, social network studies have focused a great deal of attention on random graph models of…

Applications · Statistics 2010-10-06 Mark S. Handcock , Krista J. Gile

The field of neuroscience is facing an unprecedented expanse in the volume and diversity of available data. Traditionally, network models have provided key insights into the structure and function of the brain. With the advent of big data…

Neurons and Cognition · Quantitative Biology 2018-02-14 Michael Vaiana , Sarah Muldoon