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Early detection of lung cancer is essential in reducing mortality. Recent studies have demonstrated the clinical utility of low-dose computed tomography (CT) to detect lung cancer among individuals selected based on very limited clinical…

Computer Vision and Pattern Recognition · Computer Science 2019-02-25 Jiachen Wang , Riqiang Gao , Yuankai Huo , Shunxing Bao , Yunxi Xiong , Sanja L. Antic , Travis J. Osterman , Pierre P. Massion , Bennett A. Landman

Lung cancer follow-up is a complex, error prone, and time consuming task for clinical radiologists. Several lung CT scan images taken at different time points of a given patient need to be individually inspected, looking for possible…

Image and Video Processing · Electrical Eng. & Systems 2019-12-24 Xavier Rafael-Palou , Anton Aubanell , Ilaria Bonavita , Mario Ceresa , Gemma Piella , Vicent Ribas , Miguel Ángel González Ballester

Recent studies have shown that lung cancer screening using annual low-dose computed tomography (CT) reduces lung cancer mortality by 20% compared to traditional chest radiography. Therefore, CT lung screening has started to be used widely…

Computer Vision and Pattern Recognition · Computer Science 2018-11-06 Gorkem Polat , Ugur Halici , Yesim Serinagaoglu Dogrusoz

Lung nodule classification is a class imbalanced problem because nodules are found with much lower frequency than non-nodules. In the class imbalanced problem, conventional classifiers tend to be overwhelmed by the majority class and ignore…

Computer Vision and Pattern Recognition · Computer Science 2017-03-22 Masaharu Sakamoto , Hiroki Nakano , Kun Zhao , Taro Sekiyama

Accurate pulmonary nodule detection is a crucial step in lung cancer screening. Computer-aided detection (CAD) systems are not routinely used by radiologists for pulmonary nodule detection in clinical practice despite their potential…

Computer Vision and Pattern Recognition · Computer Science 2019-08-28 Sunyi Zheng , Jiapan Guo , Xiaonan Cui , Raymond N. J. Veldhuis , Matthijs Oudkerk , Peter M. A. van Ooijen

Lung cancer is a global and dangerous disease, and its early detection is crucial to reducing the risks of mortality. In this regard, it has been of great interest in developing a computer-aided system for pulmonary nodules detection as…

Computer Vision and Pattern Recognition · Computer Science 2018-07-30 Bum-Chae Kim , Jun-Sik Choi , Heung-Il Suk

Lung cancer is a primary contributor to cancer-related mortality globally, highlighting the necessity for precise early detection of pulmonary nodules through low-dose CT (LDCT) imaging. Deep learning methods have improved nodule detection…

Quantitative Methods · Quantitative Biology 2025-12-10 Fateme Mobini , Mohammad Reza Hedyehzadeh , Mahdi Yousefi

In this paper, we investigate the effectiveness of deep learning techniques for lung nodule classification in computed tomography scans. Using less than 10,000 training examples, our deep networks perform two times better than a standard…

Computer Vision and Pattern Recognition · Computer Science 2018-09-10 Aryan Mobiny , Supratik Moulik , Hien Van Nguyen

Early detection of lung cancer is critical to improving survival outcomes. We present a deep learning framework for automated lung cancer screening from chest computed tomography (CT) images with integrated explainability. Using the…

Image and Video Processing · Electrical Eng. & Systems 2026-01-07 Nishan Rai , Sujan Khatri , Devendra Risal

The accurate classification of benign and malignant pulmonary nodules in CT scans is critical for early lung cancer screening, yet remains challenging due to the multi-scale and heterogeneous nature of pulmonary nodules. While deep learning…

Computer Vision and Pattern Recognition · Computer Science 2026-05-14 Jinyue Li , Yuzhou Yu , Jingjing Yang , Meng Fu , Yani Zhang , Shuyao He , Dianlong Ge , Xin Ning , Yannan Chu , Qiankun Li

Recent evolution in deep learning has proven its value for CT-based lung nodule classification. Most current techniques are intrinsically black-box systems, suffering from two generalizability issues in clinical practice. First,…

Image and Video Processing · Electrical Eng. & Systems 2022-02-28 Hanxiao Zhang , Liang Chen , Xiao Gu , Minghui Zhang , Yulei Qin , Feng Yao , Zhexin Wang , Yun Gu , Guang-Zhong Yang

In the U.S., lung cancer is the second major cause of death. Early detection of suspicious lung nodules is crucial for patient treatment planning, management, and improving outcomes. Many approaches for lung nodule segmentation and…

Image and Video Processing · Electrical Eng. & Systems 2025-04-10 Tejas Sudharshan Mathai , Benjamin Hou , Ronald M. Summers

Lung cancer is the leading cause of cancer deaths. Early detection through low-dose computed tomography (CT) screening has been shown to significantly reduce mortality but suffers from a high false positive rate that leads to unnecessary…

Image and Video Processing · Electrical Eng. & Systems 2019-06-04 Jason L. Causey , Yuanfang Guan , Wei Dong , Karl Walker , Jake A. Qualls , Fred Prior , Xiuzhen Huang

Early detection of malignant lung nodules remains constrained by size and growth based screening criteria, often delaying diagnosis. We present an integrated AI system that jointly performs nodule detection and malignancy assessment…

Convolutional neural networks (CNNs) have shown great promise in improving computer aided detection (CADe). From classifying tumors found via mammography as benign or malignant to automated detection of colorectal polyps in CT colonography,…

Computer Vision and Pattern Recognition · Computer Science 2019-07-30 Hunter Park , Connor Monahan

Recently, intelligent analysis of lung nodules with the assistant of computer aided detection (CAD) techniques can improve the accuracy rate of lung cancer diagnosis. However, existing CAD systems and pulmonary datasets mainly focus on…

Image and Video Processing · Electrical Eng. & Systems 2024-06-27 Muwei Jian , Haoran Zhang , Mingju Shao , Hongyu Chen , Huihui Huang , Yanjie Zhong , Changlei Zhang , Bin Wang , Penghui Gao

Though large-scale datasets are essential for training deep learning systems, it is expensive to scale up the collection of medical imaging datasets. Synthesizing the objects of interests, such as lung nodules, in medical images based on…

Computer Vision and Pattern Recognition · Computer Science 2019-01-01 Jie Yang , Siqi Liu , Sasa Grbic , Arnaud Arindra Adiyoso Setio , Zhoubing Xu , Eli Gibson , Guillaume Chabin , Bogdan Georgescu , Andrew F. Laine , Dorin Comaniciu

In this work we present a method for lung nodules segmentation, their texture classification and subsequent follow-up recommendation from the CT image of lung. Our method consists of neural network model based on popular U-Net architecture…

Image and Video Processing · Electrical Eng. & Systems 2020-06-29 Alexandr G. Rassadin

This paper proposes a novel and efficient method to build a Computer-Aided Diagnoses (CAD) system for lung nodule detection based on Computed Tomography (CT). This task was treated as an Object Detection on Video (VID) problem by imitating…

Computer Vision and Pattern Recognition · Computer Science 2017-12-15 Ning Li , Haopeng Liu , Bin Qiu , Wei Guo , Shijun Zhao , Kungang Li , Jie He

Lung cancer is the commonest cause of cancer deaths worldwide, and its mortality can be reduced significantly by performing early diagnosis and screening. Since the 1960s, driven by the pressing needs to accurately and effectively interpret…

Computer Vision and Pattern Recognition · Computer Science 2020-04-27 Bo Liu , Wenhao Chi , Xinran Li , Peng Li , Wenhua Liang , Haiping Liu , Wei Wang , Jianxing He
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