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Density functional theory (DFT) is one of the main methods in Quantum Chemistry that offers an attractive trade off between the cost and accuracy of quantum chemical computations. The electron density plays a key role in DFT. In this work,…

Chemical Physics · Physics 2018-09-11 Anton V. Sinitskiy , Vijay S. Pande

Machine learning techniques have found their way into computational chemistry as indispensable tools to accelerate atomistic simulations and materials design. In addition, machine learning approaches hold the potential to boost the…

Chemical Physics · Physics 2025-10-03 Johannes Voss

Large scale Density Functional Theory (DFT) based electronic structure calculations are highly time consuming and scale poorly with system size. While semi-empirical approximations to DFT result in a reduction in computational time versus…

Materials Science · Physics 2016-12-21 Ganesh Hegde , R. Chris Bowen

The ground state electron density -- obtainable using Kohn-Sham Density Functional Theory (KS-DFT) simulations -- contains a wealth of material information, making its prediction via machine learning (ML) models attractive. However, the…

The integration of density functional theory (DFT) with machine learning enables efficient \textit{ab initio} electronic structure calculations for ultra-large systems. In this work, we develop a transfer learning framework tailored for…

Materials Science · Physics 2025-01-23 Ting Bao , Ning Mao , Wenhui Duan , Yong Xu , Adrian Del Maestro , Yang Zhang

The properties of electrons in matter are of fundamental importance. They give rise to virtually all molecular and material properties and determine the physics at play in objects ranging from semiconductor devices to the interior of giant…

Deep neural networks trained on a wide range of datasets demonstrate impressive transferability. Deep features appear general in that they are applicable to many datasets and tasks. Such property is in prevalent use in real-world…

Machine Learning · Computer Science 2019-09-27 Hong Liu , Mingsheng Long , Jianmin Wang , Michael I. Jordan

Data-driven approaches such as deep learning can result in predictive models for material properties with exceptional accuracy and efficiency. However, in many applications, data is sparse, severely limiting their accuracy and…

Machine Learning · Computer Science 2025-10-29 Robert J Appleton , Brian C Barnes , Alejandro Strachan

Deep learning is known to be data-hungry, which hinders its application in many areas of science when datasets are small. Here, we propose to use transfer learning methods to migrate knowledge between different physical scenarios and…

Computer Vision and Pattern Recognition · Computer Science 2019-05-06 Yurui Qu , Li Jing , Yichen Shen , Min Qiu , Marin Soljacic

Transfer learning has emerged as a powerful methodology for adapting pre-trained deep neural networks on image recognition tasks to new domains. This process consists of taking a neural network pre-trained on a large feature-rich source…

Machine Learning · Computer Science 2021-04-27 Francisco Utrera , Evan Kravitz , N. Benjamin Erichson , Rajiv Khanna , Michael W. Mahoney

Predicting interfacial thermodynamics across molecular and continuum scales remains a central challenge in computational science. Classical density functional theory (cDFT) provides a first-principles route to connect microscopic…

Computational Physics · Physics 2026-01-01 Edoardo Monti , Peter Yatsyshin , Konstantinos Gkagkas , Andrew B. Duncan

We present an extension of reverse engineered Kohn-Sham potentials from a density matrix renormalization group calculation towards the construction of a density functional theory functional via deep learning. Instead of applying machine…

Disordered Systems and Neural Networks · Physics 2021-05-05 Peter Schmitteckert

High-throughput computational screening has emerged as a critical component of materials discovery. Direct density functional theory (DFT) simulation of inorganic materials and molecular transition metal complexes is often used to describe…

Materials Science · Physics 2017-05-18 Jon Paul Janet , Heather J. Kulik

With rapid progress in deep learning, neural networks have been widely used in scientific research and engineering applications as surrogate models. Despite the great success of neural networks in fitting complex systems, two major…

Machine Learning · Computer Science 2023-06-13 Yuwen Deng , Wang Kang , Wei W. Xing

Transfer learning is widely used to adapt large pretrained models to new tasks with only a small amount of new data. However, a challenge persists -- the features from the original task often do not fully cover what is needed for unseen…

Machine Learning · Computer Science 2026-02-10 Xingyu Alice Yang , Jianyu Zhang , Léon Bottou

We develop new algorithms for estimating heterogeneous treatment effects, combining recent developments in transfer learning for neural networks with insights from the causal inference literature. By taking advantage of transfer learning,…

The use of machine learning in chemistry has become a common practice. At the same time, despite the success of modern machine learning methods, the lack of data limits their use. Using a transfer learning methodology can help solve this…

Machine Learning · Computer Science 2021-07-26 Kirill Karpov , Artem Mitrofanov , Vadim Korolev , Valery Tkachenko

Transfer learning with models pretrained on ImageNet has become a standard practice in computer vision. Transfer learning refers to fine-tuning pretrained weights of a neural network on a downstream task, typically unrelated to ImageNet.…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Xander Coetzer , Arné Schreuder , Anna Sergeevna Bosman

Recently, sophisticated deep learning-based approaches have been developed for generating efficient initial guesses to accelerate the convergence of density functional theory (DFT) calculations. While the actual initial guesses are often…

Chemical Physics · Physics 2026-03-24 Zhe Liu , Yuyan Ni , Zhichen Pu , Qiming Sun , Siyuan Liu , Wen Yan

Neural Network Potentials (NNPs) have attracted significant attention as a method for accelerating density functional theory (DFT) calculations. However, conventional NNP models typically do not incorporate spin degrees of freedom, limiting…

Materials Science · Physics 2024-09-10 Koki Ueno , Satoru Ohuchi , Kazuhide Ichikawa , Kei Amii , Kensuke Wakasugi