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Computational pathology, integrating computational methods and digital imaging, has shown to be effective in advancing disease diagnosis and prognosis. In recent years, the development of machine learning and deep learning has greatly…

Image and Video Processing · Electrical Eng. & Systems 2025-02-25 Jiamu Wang , Chang-Su Kim , Jin Tae Kwak

Wounds, such as foot ulcers, pressure ulcers, leg ulcers, and infected wounds, come up with substantial problems for healthcare professionals. Prompt and accurate segmentation is crucial for effective treatment. However, contemporary…

Image and Video Processing · Electrical Eng. & Systems 2024-08-22 Md. Zihad Bin Jahangir , Sumaiya Akter , MD Abdullah Al Nasim , Kishor Datta Gupta , Roy George

Background: Breast cancer has the highest prevalence in women globally. The classification and diagnosis of breast cancer and its histopathological images have always been a hot spot of clinical concern. In Computer-Aided Diagnosis (CAD),…

Computer Vision and Pattern Recognition · Computer Science 2022-05-11 Yuchao Zheng , Chen Li , Xiaomin Zhou , Haoyuan Chen , Hao Xu , Yixin Li , Haiqing Zhang , Xiaoyan Li , Hongzan Sun , Xinyu Huang , Marcin Grzegorzek

The advent of large-scale self-supervised learning (SSL) has produced a vast zoo of medical foundation models. However, selecting optimal medical foundation models for specific segmentation tasks remains a computational bottleneck. Existing…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Jiaqi Tang , Shaoyang Zhang , Xiaoqi Wang , Jiaying Zhou , Yang Liu , Qingchao Chen

The improved diagnostic accuracy of ultrasound breast examinations remains an important goal. In this study, we propose a biophysical feature based machine learning method for breast cancer detection to improve the performance beyond a…

Image and Video Processing · Electrical Eng. & Systems 2022-07-15 Jihye Baek , Avice M. O'Connell , Kevin J. Parker

Skin cancer is one of the most common cancers in the United States. As technological advancements are made, algorithmic diagnosis of skin lesions is becoming more important. In this paper, we develop algorithms for segmenting the actual…

Computer Vision and Pattern Recognition · Computer Science 2019-05-22 Yu-Min Chung , Chuan-Shen Hu , Austin Lawson , Clifford Smyth

Large Language Models (LLMs) have shown significant promise across various natural language processing tasks. However, their application in the field of pathology, particularly for extracting meaningful insights from unstructured medical…

Computation and Language · Computer Science 2025-03-04 Rachit Saluja , Jacob Rosenthal , Yoav Artzi , David J. Pisapia , Benjamin L. Liechty , Mert R. Sabuncu

Motivation: Cancer is heterogeneous, affecting the precise approach to personalized treatment. Accurate subtyping can lead to better survival rates for cancer patients. High-throughput technologies provide multiple omics data for cancer…

Machine Learning · Computer Science 2022-08-01 Hai Yang , Yuhang Sheng , Yi Jiang , Xiaoyang Fang , Dongdong Li , Jing Zhang , Zhe Wang

Topological Data Analysis (TDA) is an emergent field that aims to discover topological information hidden in a dataset. TDA tools have been commonly used to create filters and topological descriptors to improve Machine Learning (ML)…

Machine Learning · Computer Science 2022-02-07 Rolando Kindelan , José Frías , Mauricio Cerda , Nancy Hitschfeld

The expanding ecosystem of pathology foundation models has produced powerful but fragmented tile-level representations, limiting their use in clinical tasks that require unified slide-level reasoning and interpretable linkage to clinically…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Tianyang Wang , Ziyu Su , Abdul Rehman Akbar , Usama Sajjad , Lina Gokhale , Charles Rabolli , Wei Chen , Anil Parwani , Muhammad Khalid Khan Niazi

Automatic labelling of anatomical structures, such as coronary arteries, is critical for diagnosis, yet existing (non-deep learning) methods are limited by a reliance on prior topological knowledge of the expected tree-like structures. As…

Image and Video Processing · Electrical Eng. & Systems 2024-03-05 Yadan Li , Mohammad Ali Armin , Simon Denman , David Ahmedt-Aristizabal

The accurate classification of benign and malignant pulmonary nodules in CT scans is critical for early lung cancer screening, yet remains challenging due to the multi-scale and heterogeneous nature of pulmonary nodules. While deep learning…

Computer Vision and Pattern Recognition · Computer Science 2026-05-14 Jinyue Li , Yuzhou Yu , Jingjing Yang , Meng Fu , Yani Zhang , Shuyao He , Dianlong Ge , Xin Ning , Yannan Chu , Qiankun Li

Inferring biological relationships from cellular phenotypes in high-content microscopy screens provides significant opportunity and challenge in biological research. Prior results have shown that deep vision models can capture biological…

Deep learning has shown tremendous progress in a wide range of digital pathology and medical image classification tasks. Its integration into safe clinical decision-making support requires robust and reliable models. However, real-world…

Image and Video Processing · Electrical Eng. & Systems 2024-08-19 Abdur R. Fayjie , Jutika Borah , Florencia Carbone , Jan Tack , Patrick Vandewalle

Cancer is still one of the most devastating diseases of our time. One way of automatically classifying tumor samples is by analyzing its derived molecular information (i.e., its genes expression signatures). In this work, we aim to…

Machine Learning · Computer Science 2020-01-16 Mafalda Falcao Ferreira , Rui Camacho , Luis F. Teixeira

Whole-slide images (WSIs) from cancer patients contain rich information that can be used for medical diagnosis or to follow treatment progress. To automate their analysis, numerous deep learning methods based on convolutional neural…

Computer Vision and Pattern Recognition · Computer Science 2026-02-18 Lucas Sancéré , Noémie Moreau , Katarzyna Bozek

Breast cancer is one of the leading causes of mortality in women. Early detection and treatment are imperative for improving survival rates, which have steadily increased in recent years as a result of more sophisticated…

Computer Vision and Pattern Recognition · Computer Science 2018-02-27 Sulaiman Vesal , Nishant Ravikumar , AmirAbbas Davari , Stephan Ellmann , Andreas Maier

The histopathological analysis of whole-slide images (WSIs) is fundamental to cancer diagnosis but is a time-consuming and expert-driven process. While deep learning methods show promising results, dominant patch-based methods artificially…

Image and Video Processing · Electrical Eng. & Systems 2025-10-08 Alexander Weers , Alexander H. Berger , Laurin Lux , Peter Schüffler , Daniel Rueckert , Johannes C. Paetzold

Spatial arrangement of cells of various types, such as tumor infiltrating lymphocytes and the advancing edge of a tumor, are important features for detecting and characterizing cancers. However, convolutional neural networks (CNNs) do not…

Image and Video Processing · Electrical Eng. & Systems 2019-08-15 Shrey Gadiya , Deepak Anand , Amit Sethi

Prostate cancer being one of the frequently diagnosed malignancy in men, the rising demand for biopsies places a severe workload on pathologists. The grading procedure is tedious and subjective, motivating the development of automated…

Computer Vision and Pattern Recognition · Computer Science 2026-03-06 Riddhasree Bhattacharyya , Pallabi Dutta , Sushmita Mitra