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In the field of multiple hypothesis testing, combining p-values represents a fundamental statistical method. The Cauchy combination test (CCT) (Liu and Xie, 2020) excels among numerous methods for combining p-values with powerful and…

Methodology · Statistics 2024-10-17 Yanyan Ouyang , Xingwei Liu , Lixing Zhu , Wangli Xu

Globally, the outbreaks of infectious diseases have exerted an extremely profound and severe influence on health security and the economy. During the critical phases of epidemics, devising effective intervention measures poses a significant…

Machine Learning · Computer Science 2025-05-08 Baida Zhang , Yakai Chen , Huichun Li , Zhenghu Zu

Two-phase outcome dependent sampling (ODS) is widely used in many fields, especially when certain covariates are expensive and/or difficult to measure. For two-phase ODS, the conditional maximum likelihood (CML) method is very attractive…

Methodology · Statistics 2022-12-21 Menglu Che , Peisong Han , Jerald F. Lawless

We propose a modified version of the three-step estimation method for the latent class model with covariates, which may be used to estimate latent Markov models for longitudinal data. The three-step estimation approach we propose is based…

Methodology · Statistics 2014-02-06 Francesco Bartolucci , Giorgio E. Montanari , Silvia Pandolfi

Simulating the spread of infectious diseases in human communities is critical for predicting the trajectory of an epidemic and verifying various policies to control the devastating impacts of the outbreak. Many existing simulators are based…

Populations and Evolution · Quantitative Biology 2021-04-22 Arash Mehrjou , Ashkan Soleymani , Amin Abyaneh , Samir Bhatt , Bernhard Schölkopf , Stefan Bauer

The significance of efficient and accurate diagnosis amidst the unique challenges posed by the COVID-19 pandemic underscores the urgency for innovative approaches. In response to these challenges, we propose a transfer learning-based…

Image and Video Processing · Electrical Eng. & Systems 2023-12-12 Kenan Morani , Esra Kaya Ayana , Devrim Unay

The COVID-19 pandemic has impacted lives and economies across the globe, leading to many deaths. While vaccination is an important intervention, its roll-out is slow and unequal across the globe. Therefore, extensive testing still remains…

Epidemiological models with constant parameters may not capture satisfactory infection patterns in the presence of pharmaceutical and non-pharmaceutical mitigation measures during a pandemic, since infectiousness is a function of time. In…

Populations and Evolution · Quantitative Biology 2022-05-16 K. D. Olumoyin , A. Q. M. Khaliq , K. M. Furati

To deal with very large datasets a mini-batch version of the Monte Carlo Markov Chain Stochastic Approximation Expectation-Maximization algorithm for general latent variable models is proposed. For exponential models the algorithm is shown…

Computation · Statistics 2023-08-30 Tabea Rebafka , Estelle Kuhn , Catherine Matias

Nonparametric tests for equality of multivariate distributions are frequently desired in research. It is commonly required that test-procedures based on relatively small samples of vectors accurately control the corresponding Type I Error…

Methodology · Statistics 2021-01-14 Ablert Vexler , Gregory Gurevich , Li Zou

This study aims to estimate the parameters of a stochastic exposed-infected epidemiological model for the transmission dynamics of notifiable infectious diseases, based on observations related to isolated cases counts only. We use the…

Applications · Statistics 2024-04-15 Ibrahim Bouzalmat , Benoîte de Saporta , Solym M. Manou-Abi

Monitoring the evolution of the Covid19 pandemic constitutes a critical step in sanitary policy design. Yet, the assessment of the pandemic intensity within the pandemic period remains a challenging task because of the limited quality of…

Populations and Evolution · Quantitative Biology 2022-02-14 Patrice Abry , Gersende Fort , Barbara Pascal , Nelly Pustelnik

Group testing is a method of identifying infected patients by performing tests on a pool of specimens collected from patients. For the case in which the test returns a false result with finite probability, we propose Bayesian inference and…

Machine Learning · Statistics 2020-07-15 Ayaka Sakata

We consider the problem of inference for the states and parameters of a continuous-time multitype branching process from partially observed time series data. Exact inference for this class of models, typically using sequential Monte Carlo,…

Methodology · Statistics 2025-12-01 Angus Lewis , Antonio Parrella , John Maclean , Andrew J. Black

The use of group testing to locate all instances of disease in a large population of blood samples was first considered seventy years ago. Since then, several methods have been used to approximate the minimum expected number of tests. The…

Applications · Statistics 2015-03-24 Seth Zimmerman

We propose a robust parameter estimation method for dynamical systems based on Statistical Learning techniques which aims to estimate a set of parameters that well fit the dynamics in order to obtain robust evidences about the qualitative…

Methodology · Statistics 2021-02-26 Diego Marcondes

How to fast and accurately assess the severity level of COVID-19 is an essential problem, when millions of people are suffering from the pandemic around the world. Currently, the chest CT is regarded as a popular and informative imaging…

Image and Video Processing · Electrical Eng. & Systems 2021-02-09 Zekun Li , Wei Zhao , Feng Shi , Lei Qi , Xingzhi Xie , Ying Wei , Zhongxiang Ding , Yang Gao , Shangjie Wu , Jun Liu , Yinghuan Shi , Dinggang Shen

COVID-19 classification using chest Computed Tomography (CT) has been found pragmatically useful by several studies. Due to the lack of annotated samples, these studies recommend transfer learning and explore the choices of pre-trained…

Computer Vision and Pattern Recognition · Computer Science 2021-02-17 Fouzia Altaf , Syed M. S. Islam , Naeem K. Janjua , Naveed Akhtar

The usual development cycles are too slow for the development of vaccines, diagnostics and treatments in pandemics such as the ongoing SARS-CoV-2 pandemic. Given the pressure in such a situation, there is a risk that findings of early…

Applications · Statistics 2020-10-12 Sarah Friedrich , Tim Friede