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Materials informatics (MI), which uses artificial intelligence and data analysis techniques to improve the efficiency of materials development, is attracting increasing interest from industry. One of its main applications is the rapid…

Machine Learning · Computer Science 2023-02-07 Yoshihiro Osakabe , Akinori Asahara

Paradoxically, a Variational Autoencoder (VAE) could be pushed in two opposite directions, utilizing powerful decoder model for generating realistic images but collapsing the learned representation, or increasing regularization coefficient…

Machine Learning · Computer Science 2022-03-30 Trung Ngo , Najwa Laabid , Ville Hautamäki , Merja Heinäniemi

Inverse microstructure design plays a central role in materials discovery, yet remains challenging due to the complexity of structure-property linkages and the scarcity of labeled training data. We propose Design-GenNO, a physics-informed…

Mathematical Physics · Physics 2025-09-11 Yaohua Zang , Phaedon-Stelios Koutsourelakis

In data-driven drug discovery, designing molecular descriptors is a very important task. Deep generative models such as variational autoencoders (VAEs) offer a potential solution by designing descriptors as probabilistic latent vectors…

Machine Learning · Computer Science 2023-08-23 Daiki Koge , Naoaki Ono , Shigehiko Kanaya

This paper puts forward an integrated microstructure design methodology that replaces the common existing design approaches: 1) reconstruction of microstructures, 2) analyzing and quantifying material properties, and 3) inverse design of…

Materials Science · Physics 2023-07-18 Kang-Hyun Lee , Hyoung Jun Lim , Gun Jin Yun

Many deep generative models are defined as a push-forward of a Gaussian measure by a continuous generator, such as Generative Adversarial Networks (GANs) or Variational Auto-Encoders (VAEs). This work explores the latent space of such deep…

Machine Learning · Computer Science 2023-05-16 Thibaut Issenhuth , Ugo Tanielian , Jérémie Mary , David Picard

In recent years, deep generative models have been successfully adopted for various molecular design tasks, particularly in the life and material sciences. A critical challenge for pre-trained generative molecular design (GMD) models is to…

Machine Learning · Computer Science 2024-06-03 A N M Nafiz Abeer , Sanket Jantre , Nathan M Urban , Byung-Jun Yoon

Multi-modal generative models represent an important family of deep models, whose goal is to facilitate representation learning on data with multiple views or modalities. However, current deep multi-modal models focus on the inference of…

Computer Vision and Pattern Recognition · Computer Science 2020-12-25 Mihee Lee , Vladimir Pavlovic

The modern aerodynamic optimization has a strong demand for parametric methods with high levels of intuitiveness, flexibility, and representative accuracy, which cannot be fully achieved through traditional airfoil parametric techniques. In…

Fluid Dynamics · Physics 2023-05-08 Hairun Xie , Jing Wang , Miao Zhang

The sensitivity of heterogeneous energetic (HE) materials (propellants, explosives, and pyrotechnics) is critically dependent on their microstructure. Initiation of chemical reactions occurs at hot spots due to energy localization at sites…

Materials Science · Physics 2023-05-12 Sehyun Chun , Sidhartha Roy , Yen Thi Nguyen , Joseph B. Choi , H. S. Udaykumar , Stephen S. Baek

Automated design synthesis has the potential to revolutionize the modern engineering design process and improve access to highly optimized and customized products across countless industries. Successfully adapting generative Machine…

Machine Learning · Computer Science 2022-03-18 Lyle Regenwetter , Amin Heyrani Nobari , Faez Ahmed

Modern generative models are usually designed to match target distributions directly in the data space, where the intrinsic dimension of data can be much lower than the ambient dimension. We argue that this discrepancy may contribute to the…

Machine Learning · Computer Science 2020-07-02 Zijun Zhang , Ruixiang Zhang , Zongpeng Li , Yoshua Bengio , Liam Paull

The ability to generate physically plausible ensembles of variable sources is critical to the optimization of time-domain survey cadences and the training of classification models on datasets with few to no labels. Traditional data…

Instrumentation and Methods for Astrophysics · Physics 2020-05-19 Jorge Martínez-Palomera , Joshua S. Bloom , Ellianna S. Abrahams

Identifying the key microstructure representations is crucial for Computational Materials Design (CMD). However, existing microstructure characterization and reconstruction (MCR) techniques have limitations to be applied for materials…

Materials Science · Physics 2019-01-07 Zijiang Yang , Xiaolin Li , L. Catherine Brinson , Alok N. Choudhary , Wei Chen , Ankit Agrawal

Gastrointestinal (GI) imaging via Wireless Capsule Endoscopy (WCE) generates a large number of images requiring manual screening. Deep learning-based Clinical Decision Support (CDS) systems can assist screening, yet their performance relies…

Computer Vision and Pattern Recognition · Computer Science 2026-02-13 Dimitrios E. Diamantis , Dimitris K. Iakovidis

Variational autoencoders (VAEs) are a powerful class of deep generative latent variable model for unsupervised representation learning on high-dimensional data. To ensure computational tractability, VAEs are often implemented with a…

Machine Learning · Computer Science 2020-06-09 Alex Campbell , Pietro Liò

Designing frictional interfaces to exhibit prescribed macroscopic behavior is a challenging inverse problem, made difficult by the non-uniqueness of solutions and the computational cost of contact simulations. Traditional approaches rely on…

Machine Learning · Statistics 2025-11-07 Valentin Mouton , Adrien Mélot

The design of metamaterials which support unique optical responses is the basis for most thin-film nanophotonics applications. In practice this inverse design problem can be difficult to solve systematically due to the large design…

Computational Physics · Physics 2026-05-25 Andrew Lininger , Michael Hinczewski , Giuseppe Strangi

Deep generative models often perform poorly in real-world applications due to the heterogeneity of natural data sets. Heterogeneity arises from data containing different types of features (categorical, ordinal, continuous, etc.) and…

Machine Learning · Computer Science 2020-06-23 Chao Ma , Sebastian Tschiatschek , José Miguel Hernández-Lobato , Richard Turner , Cheng Zhang

In the development of locally resonant metamaterials, the physical resonator design is often omitted and replaced by an idealized mass-spring system. This paper presents a novel approach for designing multimodal resonant structures, which…

Applied Physics · Physics 2024-11-05 Sander Dedoncker , Christian Donner , Raphael Bischof , Linus Taenzer , Bart Van Damme
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