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Neural networks (NNs) have been successfully applied to solve a variety of application problems involving classification and function approximation. Although backpropagation NNs generally predict better than decision trees do for pattern…

Neural and Evolutionary Computing · Computer Science 2010-09-28 S. M. Kamruzzaman

The rapid accumulation of Electronic Health Records (EHRs) has transformed healthcare by providing valuable data that enhance clinical predictions and diagnoses. While conventional machine learning models have proven effective, they often…

Without any means of interpretation, neural networks that predict molecular properties and bioactivities are merely black boxes. We will unravel these black boxes and will demonstrate approaches to understand the learned representations…

Machine Learning · Computer Science 2019-03-19 Kristina Preuer , Günter Klambauer , Friedrich Rippmann , Sepp Hochreiter , Thomas Unterthiner

The use of Deep Neural Network (DNN) models in risk-based decision-making has attracted extensive attention with broad applications in medical, finance, manufacturing, and quality control. To mitigate prediction-related risks in decision…

Machine Learning · Statistics 2023-10-11 Maryam Kheirandish , Shengfan Zhang , Donald G. Catanzaro , Valeriu Crudu

Deep learning methods based on Convolutional Neural Networks (CNNs) have shown great potential to improve early and accurate diagnosis of Alzheimer's disease (AD) dementia based on imaging data. However, these methods have yet to be widely…

Computer Vision and Pattern Recognition · Computer Science 2025-01-22 Wenjie Kang , Lize Jiskoot , Peter De Deyn , Geert Biessels , Huiberdina Koek , Jurgen Claassen , Huub Middelkoop , Wiesje Flier , Willemijn J. Jansen , Stefan Klein , Esther Bron

Explainable Artificial Intelligence (xAI) has the potential to enhance the transparency and trust of AI-based systems. Although accurate predictions can be made using Deep Neural Networks (DNNs), the process used to arrive at such…

Computer Vision and Pattern Recognition · Computer Science 2024-08-09 Bhushan Atote , Victor Sanchez

Graph neural networks (GNNs) demonstrate great performance in compound property and activity prediction due to their capability to efficiently learn complex molecular graph structures. However, two main limitations persist including…

Biomolecules · Quantitative Biology 2023-10-10 Apakorn Kengkanna , Masahito Ohue

The recent success of brain-inspired deep neural networks (DNNs) in solving complex, high-level visual tasks has led to rising expectations for their potential to match the human visual system. However, DNNs exhibit idiosyncrasies that…

Neurons and Cognition · Quantitative Biology 2019-05-08 Chihye Han , Wonjun Yoon , Gihyun Kwon , Seungkyu Nam , Daeshik Kim

In recent years, deep neural networks have been applied to obtain high performance of prediction, classification, and pattern recognition. However, the weights in these deep neural networks are difficult to be explained. Although a linear…

Machine Learning · Computer Science 2020-05-08 Chi-Hua Chen

Deep learning models are favored in many research and industry areas and have reached the accuracy of approximating or even surpassing human level. However they've long been considered by researchers as black-box models for their…

Machine Learning · Computer Science 2020-10-16 Xiaojian Wang , Jingyuan Wang , Ke Tang

Deep neural networks have demonstrated remarkable performance across various domains, yet their decision-making processes remain opaque. Although many explanation methods are dedicated to bringing the obscurity of DNNs to light, they…

Computer Vision and Pattern Recognition · Computer Science 2025-12-17 Kanglong Fan , Yunqiao Yang , Chen Ma

As the use of deep learning techniques has grown across various fields over the past decade, complaints about the opaqueness of the black-box models have increased, resulting in an increased focus on transparency in deep learning models.…

Computation and Language · Computer Science 2024-03-19 Siwen Luo , Hamish Ivison , Caren Han , Josiah Poon

Although deep reinforcement learning has been shown to be effective, the model's black-box nature presents barriers to direct policy interpretation. To address this problem, we propose a neuro-symbolic approach called neural DNF-MT for…

Artificial Intelligence · Computer Science 2025-04-25 Kexin Gu Baugh , Luke Dickens , Alessandra Russo

Deep neural networks (DNNs) are being increasingly used to make predictions from functional magnetic resonance imaging (fMRI) data. However, they are widely seen as uninterpretable "black boxes", as it can be difficult to discover what…

Machine Learning · Computer Science 2020-12-18 Patrick McClure , Dustin Moraczewski , Ka Chun Lam , Adam Thomas , Francisco Pereira

What might sound like the beginning of a joke has become an attractive prospect for many cognitive scientists: the use of deep neural network models (DNNs) as models of human behavior in perceptual and cognitive tasks. Although DNNs have…

Artificial Intelligence · Computer Science 2020-05-06 Wei Ji Ma , Benjamin Peters

Building generalizable AI models is one of the primary challenges in the healthcare domain. While radiologists rely on generalizable descriptive rules of abnormality, Neural Network (NN) models suffer even with a slight shift in input…

Computer Vision and Pattern Recognition · Computer Science 2023-07-12 Shantanu Ghosh , Ke Yu , Kayhan Batmanghelich

Fetal standard scan plane detection during 2-D mid-pregnancy examinations is a highly complex task, which requires extensive medical knowledge and years of training. Although deep neural networks (DNN) can assist inexperienced operators in…

Machine Learning · Computer Science 2026-03-09 Yingni Wanga , Yunxiao Liua , Licong Dongc , Xuzhou Wua , Huabin Zhangb , Qiongyu Yed , Desheng Sunc , Xiaobo Zhoue , Kehong Yuan

The black-box nature of deep learning models prevents them from being completely trusted in domains like biomedicine. Most explainability techniques do not capture the concept-based reasoning that human beings follow. In this work, we…

Computer Vision and Pattern Recognition · Computer Science 2022-03-15 Avinash Kori , Parth Natekar , Ganapathy Krishnamurthi , Balaji Srinivasan

Self-explaining models are models that reveal decision making parameters in an interpretable manner so that the model reasoning process can be directly understood by human beings. General Linear Models (GLMs) are self-explaining because the…

Machine Learning · Computer Science 2019-05-31 Yingjing Lu , Runde Yang

Electrocardiogram (ECG) is the most widely used diagnostic tool to monitor the condition of the human heart. By using deep neural networks (DNNs), interpretation of ECG signals can be fully automated for the identification of potential…

Machine Learning · Computer Science 2022-03-16 Linhai Ma , Liang Liang
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