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Missing data often exists in real-world datasets, requiring significant time and effort for data repair to learn accurate models. In this paper, we show that imputing all missing values is not always necessary to achieve an accurate ML…

Machine Learning · Computer Science 2026-03-19 Cheng Zhen , Prayoga , Nischal Aryal , Arash Termehchy , Garrett Biwer , Lubna Alzamil

The wide implementation of electronic health record (EHR) systems facilitates the collection of large-scale health data from real clinical settings. Despite the significant increase in adoption of EHR systems, this data remains largely…

Quantitative Methods · Quantitative Biology 2018-10-26 Jinghe Zhang , Kamran Kowsari , James H. Harrison , Jennifer M. Lobo , Laura E. Barnes

Electronic health records (EHRs) are multimodal by nature, consisting of structured tabular features like lab tests and unstructured clinical notes. In real-life clinical practice, doctors use complementary multimodal EHR data sources to…

Computation and Language · Computer Science 2024-07-18 Thao Minh Nguyen Phan , Cong-Tinh Dao , Chenwei Wu , Jian-Zhe Wang , Shun Liu , Jun-En Ding , David Restrepo , Feng Liu , Fang-Ming Hung , Wen-Chih Peng

The use of flexible machine-learning (ML) models to generate imputations of missing data within the framework of Multiple Imputation (MI) has recently gained traction, particularly in observational settings. For randomised controlled trials…

Methodology · Statistics 2025-10-07 Mia S. Tackney , Jonathan W. Bartlett , Elizabeth Williamson , Kim May Lee

Learning structures between groups of variables from data with missing values is an important task in the real world, yet difficult to solve. One typical scenario is discovering the structure among topics in the education domain to identify…

Electronic health records (EHR) data provide a cost and time-effective opportunity to conduct cohort studies of the effects of multiple time-point interventions in the diverse patient population found in real-world clinical settings.…

Deep learning models have shown tremendous potential in learning representations, which are able to capture some key properties of the data. This makes them great candidates for transfer learning: Exploiting commonalities between different…

Clinical text improvement is vital for healthcare efficiency but remains difficult due to limited high-quality data and the complex constraints of medical documentation. While Large Language Models (LLMs) show promise, current approaches…

Computation and Language · Computer Science 2026-02-03 Ziyan Xiao , Yinghao Zhu , Liang Peng , Lequan Yu

Deep latent variable models (DLVMs) combine the approximation abilities of deep neural networks and the statistical foundations of generative models. Variational methods are commonly used for inference; however, the exact likelihood of…

Machine Learning · Statistics 2018-06-29 Pierre-Alexandre Mattei , Jes Frellsen

Recent advances in large language models (LLMs) have enabled promising progress in diagnosis prediction from electronic health records (EHRs). However, existing LLM-based approaches tend to overfit to historically observed diagnoses, often…

Computation and Language · Computer Science 2026-04-14 Hengyu Zhang , Xuyun Zhang , Pengxiang Zhan , Linhao Luo , Hang Lv , Yanchao Tan , Shirui Pan , Carl Yang

Evidence-based medicine (EBM) holds a crucial role in clinical application. Given suitable medical articles, doctors effectively reduce the incidence of misdiagnoses. Researchers find it efficient to use large language models (LLMs)…

Computation and Language · Computer Science 2025-11-07 Mengzhou Sun , Sendong Zhao , Jianyu Chen , Haochun Wang , Bing Qin

Electronic medical records (EMRs) contain essential data for patient care and clinical research. With the diversity of structured and unstructured data in EHR, data visualization is an invaluable tool for managing and explaining these…

Databases · Computer Science 2025-06-17 Haodi Zhang , Siqi Ning , Qiyong Zheng , Jinyin Nie , Liangjie Zhang , Weicheng Wang , Yuanfeng Song

Machine learning techniques have been developed to learn from complete data. When missing values exist in a dataset, the incomplete data should be preprocessed separately by removing data points with missing values or imputation. In this…

Machine Learning · Computer Science 2020-12-25 Hadi A. Khorshidi , Michael Kirley , Uwe Aickelin

This study investigates the impact of quantity and diversity of data on the performance of various machine-learning models for detecting general EEG pathology. We utilized an EEG dataset of 2,993 recordings from Temple University Hospital…

Empirical risk minimization (ERM) is sensitive to spurious correlations in the training data, which poses a significant risk when deploying systems trained under this paradigm in high-stake applications. While the existing literature…

Machine Learning · Computer Science 2023-10-31 Christos Tsirigotis , Joao Monteiro , Pau Rodriguez , David Vazquez , Aaron Courville

Misdiagnosis is a significant issue in healthcare, leading to harmful consequences for patients. The propagation of mislabeled data through machine learning models into clinical practice is unacceptable. This paper proposes EVINCE, a system…

Artificial Intelligence · Computer Science 2024-05-29 Edward Y. Chang

This work proposes a variational inference (VI) framework for hyperspectral unmixing in the presence of endmember variability (HU-EV). An EV-accounted noisy linear mixture model (LMM) is considered, and the presence of outliers is also…

Machine Learning · Computer Science 2024-07-23 Yuening Li , Xiao Fu , Junbin Liu , Wing-Kin Ma

Missing data is an universal problem in statistics. We develop a unified framework for estimating parameters defined by general estimating equations under a missing-at-random (MAR) mechanism, based on generalized entropy calibration…

Methodology · Statistics 2026-03-31 Mst Moushumi Pervin , Hengfang Wang , Jae Kwang Kim

In the dynamic hospital setting, decision support can be a valuable tool for improving patient outcomes. Data-driven inference of future outcomes is challenging in this dynamic setting, where long sequences such as laboratory tests and…

Quantitative Methods · Quantitative Biology 2024-04-25 Alan D. Kaplan , Priyadip Ray , John D. Greene , Vincent X. Liu

Accurate imputation of missing laboratory values in electronic health records (EHRs) is critical to enable robust clinical predictions and reduce biases in AI systems in healthcare. Existing methods, such as XGBoost, softimpute, GAIN,…

Machine Learning · Computer Science 2025-06-27 David Restrepo , Chenwei Wu , Yueran Jia , Jaden K. Sun , Jack Gallifant , Catherine G. Bielick , Yugang Jia , Leo A. Celi
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