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From footpaths to flight routes, human mobility networks facilitate the spread of communicable diseases. Control and elimination efforts depend on characterizing these networks in terms of connections and flux rates of individuals between…

Populations and Evolution · Quantitative Biology 2016-01-29 Kyle B Gustafson , Basil S. Bayati , Philip A. Eckhoff

We consider a model for an influenza-like disease, in which, between seasons, the virus makes a random genetic drift $\delta$, (reducing immunity by the factor $\delta$) and obtains a new random transmissibility $\tau$ (closely related to…

Probability · Mathematics 2025-05-26 Tom Britton , Andrea Pugliese

Rapidly mutating pathogens may be able to persist in the population and reach an endemic equilibrium by escaping hosts' acquired immunity. For such diseases, multiple biological, environmental and population-level mechanisms determine the…

Physics and Society · Physics 2019-02-07 Alberto Aleta , Andreia N. S. Hisi , Sandro Meloni , Chiara Poletto , Vittoria Colizza , Yamir Moreno

We study a class of individual-based, fixed-population size epidemic models under general assumptions, e.g., heterogeneous contact rates encapsulating changes in behavior and/or enforcement of control measures. We show that the…

Probability · Mathematics 2023-07-04 Jean-Jil Duchamps , Félix Foutel-Rodier , Emmanuel Schertzer

We study a multilayer SIR model with two levels of mixing, namely a global level which is uniformly mixing, and a local level with two layers distinguishing household and workplace contacts, respectively. We establish the large population…

Probability · Mathematics 2023-10-27 Madeleine Kubasch

We consider an SIR-type (Susceptible $\to$ Infected $\to$ Recovered) stochastic epidemic process with multiple modes of transmission on a contact network. The network is given by a random graph following a multilayer configuration model…

Populations and Evolution · Quantitative Biology 2018-08-22 Karly A. Jacobsen , Mark G. Burch , Joseph H. Tien , Grzegorz A. Rempała

The mathematical model of the spread of the epidemic is developed, which considers fluctuations in the number of human social contacts. The model is based on the logistic equation. The oscillation in the number of social contacts within one…

Physics and Society · Physics 2021-06-01 S. P. Fisenko , P. S. Grinchuk

We study the influence of heterogeneous mobility patterns in a population on the SIS epidemic model. In particular, we consider a patchy environment in which each patch comprises individuals belonging the different classes, e.g.,…

Systems and Control · Electrical Eng. & Systems 2020-03-31 Vishal Abhishek , Vaibhav Srivastava

We investigate the spread of an infection or other malfunction of cascading nature when a system component can recover only if it remains reachable from a functioning central component. We consider the susceptible-infected-susceptible…

Physics and Society · Physics 2016-04-27 L. Böttcher , O. Woolley-Meza , E. Goles , D. Helbing , H. J. Herrmann

Much traditional statistical modelling assumes that the outcome variables of interest are independent of each other when conditioned on the explanatory variables. This assumption is strongly violated in the case of infectious diseases,…

Populations and Evolution · Quantitative Biology 2019-11-28 Timothy Kinyanjui , Thomas House

To forecast the time dynamics of an epidemic, we propose a discrete stochastic model that unifies and generalizes previous approaches to the subject. Viewing a given population of individuals or groups of individuals with given health state…

Insect-borne diseases are diseases carried by insects affecting humans, animals or plants. They have the potential to generate massive outbreaks such as the Zika epidemic in 2015-2016 mostly distributed in the Americas, the Pacific and…

Analysis of PDEs · Mathematics 2020-02-19 Olivier Martin , Yasmil Fernandez-Diclo , Jerome Coville , Samuel Soubeyrand

We study the Susceptible-Infected-Recovered model in complex networks, considering that not all individuals in the population interact in the same way between them. This heterogeneity between contacts is modeled by a continuous disorder. In…

Physics and Society · Physics 2013-01-01 C. Buono , C. Lagorio , P. A. Macri , L. A. Braunstein

Epidemiological models for the spread of pathogens in a population are usually only able to describe a single pathogen. This makes their application unrealistic in cases where multiple pathogens with similar symptoms are spreading…

Social and Information Networks · Computer Science 2018-05-16 Nir Levy , Michael Iv , Elad Yom-Tov

This study aims to estimate the parameters of a stochastic exposed-infected epidemiological model for the transmission dynamics of notifiable infectious diseases, based on observations related to isolated cases counts only. We use the…

Applications · Statistics 2024-04-15 Ibrahim Bouzalmat , Benoîte de Saporta , Solym M. Manou-Abi

We extend our BDI (birth-death-immigration) process based stochastic model of an infectious disease to time-nonhomogeneous cases. First, we discuss the deterministic model, and derive the expected value of the infection process. Then as an…

Methodology · Statistics 2021-01-25 Hisashi Kobayashi

In the present work we derive a Central Limit Theorem for sequences of Hilbert-valued Piecewise Deterministic Markov process models and their global fluctuations around their deterministic limit identified by the Law of Large Numbers. We…

Probability · Mathematics 2013-04-23 Martin G Riedler , Michele Thieullen

In this paper, the authors develop a method of detecting correlations between epidemic patterns in different regions that are due to human movement and introduce a null model in which the travel-induced correlations are cancelled. They…

Populations and Evolution · Quantitative Biology 2008-06-24 Pascal Crépey , Marc Barthélemy

Infectious pathogens often propagate by superspreading, which focusses onward transmission on disproportionately few infected individuals. At the same time, infector-infectee pairs tend to have more similar transmission potentials than…

Populations and Evolution · Quantitative Biology 2025-09-22 Noah Silva de Leonardi , Benjamin D. Dalziel

We introduce and analyze coupled, multi-strain epidemic models designed to simulate the emergence and dissemination of mutant (e.g. drug-resistant) pathogen strains. In particular, we investigate the mathematical and biological properties…

Populations and Evolution · Quantitative Biology 2017-05-10 Michael T. Meehan , Daniel G. Cocks , James M. Trauer , Emma S. McBryde