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Deep learning has led to significant advances in artificial intelligence, in part, by adopting strategies motivated by neurophysiology. However, it is unclear whether deep learning could occur in the real brain. Here, we show that a deep…

Neurons and Cognition · Quantitative Biology 2017-04-11 Jordan Guergiuev , Timothy P. Lillicrap , Blake A. Richards

The algorithm of brain learning and memory is still undetermined. The backpropagation algorithm of artificial neural networks was thought not suitable for brain cortex, and there is a lack of algorithm for memory engram. We designed a brain…

Neural and Evolutionary Computing · Computer Science 2020-10-29 Yifei Mao

Equilibrium Propagation (EP) is a biologically inspired local learning rule first proposed for convergent recurrent neural networks (CRNNs), in which synaptic updates depend only on neuron states from two distinct phases. EP estimates…

Machine Learning · Computer Science 2026-05-11 Jiaqi Lin , Malyaban Bal , Abhronil Sengupta

In this paper, deep neural network (DNN) is utilized to improve the belief propagation (BP) detection for massive multiple-input multiple-output (MIMO) systems. A neural network architecture suitable for detection task is firstly introduced…

Signal Processing · Electrical Eng. & Systems 2018-04-06 Xiaosi Tan , Weihong Xu , Yair Be'ery , Zaichen Zhang , Xiaohu You , Chuan Zhang

Backpropagation is a cornerstone algorithm in training neural networks for supervised learning, which uses a gradient descent method to update network weights by minimizing the discrepancy between actual and desired outputs. Despite its…

While next-token prediction (NTP) has been the standard objective for training language models, it often struggles to capture global structure in reasoning tasks. Multi-token prediction (MTP) has recently emerged as a promising alternative,…

Machine Learning · Computer Science 2026-04-15 Jianhao Huang , Zhanpeng Zhou , Renqiu Xia , Baharan Mirzasoleiman , Weijie Su , Wei Huang

Inspired by key neuroscience principles, deep learning has driven exponential breakthroughs in developing functional models of perception and other cognitive processes. A key to this success has been the implementation of crucial features…

Neurons and Cognition · Quantitative Biology 2025-11-07 Guillaume Etter

Backpropagation (BP) is a core component of the contemporary deep learning incarnation of neural networks. Briefly, BP is an algorithm that exploits the computational architecture of neural networks to efficiently evaluate the gradient of a…

Machine Learning · Statistics 2021-07-21 Dirk Ostwald , Franziska Usée

Backpropagation has long been criticized for being biologically implausible due to its reliance on concepts that are not viable in natural learning processes. Two core issues are the weight transport and update locking problems caused by…

Machine Learning · Computer Science 2026-01-14 Katharina Flügel , Daniel Coquelin , Marie Weiel , Charlotte Debus , Achim Streit , Markus Götz

Graph convolutional neural networks have recently shown great potential for the task of zero-shot learning. These models are highly sample efficient as related concepts in the graph structure share statistical strength allowing…

Computer Vision and Pattern Recognition · Computer Science 2019-03-28 Michael Kampffmeyer , Yinbo Chen , Xiaodan Liang , Hao Wang , Yujia Zhang , Eric P. Xing

Throughout this paper, we focus on the improvement of the direct feedback alignment (DFA) algorithm and extend the usage of the DFA to convolutional and recurrent neural networks (CNNs and RNNs). Even though the DFA algorithm is…

Machine Learning · Computer Science 2020-06-25 Donghyeon Han , Gwangtae Park , Junha Ryu , Hoi-jun Yoo

Deep learning models have gained great success in many real-world applications. However, most existing networks are typically designed in heuristic manners, thus lack of rigorous mathematical principles and derivations. Several recent…

Computer Vision and Pattern Recognition · Computer Science 2017-12-18 Risheng Liu , Xin Fan , Shichao Cheng , Xiangyu Wang , Zhongxuan Luo

Attribution methods aim to explain a neural network's prediction by highlighting the most relevant image areas. A popular approach is to backpropagate (BP) a custom relevance score using modified rules, rather than the gradient. We analyze…

Machine Learning · Computer Science 2024-02-20 Leon Sixt , Maximilian Granz , Tim Landgraf

Interest in biologically inspired alternatives to backpropagation is driven by the desire to both advance connections between deep learning and neuroscience and address backpropagation's shortcomings on tasks such as online, continual…

Neural and Evolutionary Computing · Computer Science 2020-06-18 Jack Lindsey , Ashok Litwin-Kumar

Backpropagation (BP) of errors is the backbone training algorithm for artificial neural networks (ANNs). It updates network weights through gradient descent to minimize a loss function representing the mismatch between predictions and…

Machine Learning · Statistics 2025-08-13 Davide Casnici , Charlotte Frenkel , Justin Dauwels

The Backpropagation algorithm relies on the abstraction of using a neural model that gets rid of the notion of time, since the input is mapped instantaneously to the output. In this paper, we claim that this abstraction of ignoring time,…

Machine Learning · Computer Science 2020-06-19 Alessandro Betti , Marco Gori

We propose a new learning framework, signal propagation (sigprop), for propagating a learning signal and updating neural network parameters via a forward pass, as an alternative to backpropagation. In sigprop, there is only the forward path…

Machine Learning · Computer Science 2022-11-18 Adam Kohan , Edward A. Rietman , Hava T. Siegelmann

Derived from the regular perturbation treatment of the nonlinear Schrodinger equation, a machine learning-based scheme to mitigate the intra-channel optical fiber nonlinearity is proposed. Referred to as the perturbation theory-aided (PA)…

Signal Processing · Electrical Eng. & Systems 2022-04-06 Xiang Lin , Shenghang Luo , Sunish Kumar Orappanpara Soman , Octavia A. Dobre , Lutz Lampe , Deyuan Chang , Chuandong Li

Backpropagation is the default algorithm for training deep neural networks due to its simplicity, efficiency and high convergence rate. However, its requirements make it impossible to be implemented in a human brain. In recent years, more…

Machine Learning · Computer Science 2021-09-01 Albert Jiménez Sanfiz , Mohamed Akrout

The backpropagation algorithm remains the dominant and most successful method for training deep neural networks (DNNs). At the same time, training DNNs at scale comes at a significant computational cost and therefore a high carbon…

Machine Learning · Computer Science 2025-11-12 Sander Dalm , Joshua Offergeld , Nasir Ahmad , Marcel van Gerven
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