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Horizontal gene transfer (HGT) is an important process in bacterial evolution. Current phylogeny-based approaches to capture it cannot however appropriately account for the fact that HGT can occur between bacteria living in different…

Populations and Evolution · Quantitative Biology 2025-03-31 Katharina T. Huber , Darren Overman

Manifold alignment is a type of data fusion technique that creates a shared low-dimensional representation of data collected from multiple domains, enabling cross-domain learning and improved performance in downstream tasks. This paper…

Machine Learning · Computer Science 2024-11-26 Jake S. Rhodes , Adam G. Rustad

A phylogenetic tree is a way to organize a finite set of species, individuals or other sources of related data. The species for which we have existing DNA data make up the set of leaves of the tree. The balanced minimal evolution method of…

Combinatorics · Mathematics 2016-08-05 Stefan Forcey , Logan Keefe , William Sands

In molecular phylogeny, relationships among organisms are reconstructed using DNA or protein sequences and are displayed as trees. A linear increase in the number of sequences results in an exponential increase of possible trees. Thus,…

Genomics · Quantitative Biology 2007-05-23 Kerstin Hoef-Emden

Since their recent introduction, process trees have been frequently used as a process modeling formalism in many process mining algorithms. A process tree is a tree-based model of a process, in which internal vertices represent behavioral…

Logic in Computer Science · Computer Science 2020-11-04 Sebastiaan J. van Zelst

Random forests have become an established tool for classification and regression, in particular in high-dimensional settings and in the presence of complex predictor-response relationships. For bounded outcome variables restricted to the…

Methodology · Statistics 2019-01-21 Leonie Weinhold , Matthias Schmid , Marvin N. Wright , Moritz Berger

Phylogenetic diversity is a measure for describing how much of an evolutionary tree is spanned by a subset of species. If one applies this to the (unknown) subset of current species that will still be present at some future time, then this…

Subcellular Processes · Quantitative Biology 2009-09-29 Beata Faller , Fabio Pardi , Mike Steel

Given a gene tree and a species tree, ancestral configurations represent the combinatorially distinct sets of gene lineages that can reach a given node of the species tree. They have been introduced as a data structure for use in the…

Populations and Evolution · Quantitative Biology 2016-10-25 Filippo Disanto , Noah A. Rosenberg

Phylogenomics heavily relies on well-curated sequence data sets that consist, for each gene, exclusively of 1:1-orthologous. Paralogs are treated as a dangerous nuisance that has to be detected and removed. We show here that this severe…

Discrete Mathematics · Computer Science 2017-12-19 Marc Hellmuth , Nicolas Wieseke , Marcus Lechner , Hans-Peter Lenhof , Martin Middendorf , Peter F. Stadler

Ranked tree-child networks are a recently introduced class of rooted phylogenetic networks in which the evolutionary events represented by the network are ordered so as to respect the flow of time. This class includes the well-studied…

Populations and Evolution · Quantitative Biology 2024-10-15 Vincent Moulton , Andreas Spillner

Identifying undocumented or potential future interactions among species is a challenge facing modern ecologists. Recent link prediction methods rely on trait data, however large species interaction databases are typically sparse and…

Applications · Statistics 2019-09-23 Mohamad Elmasri , Maxwell J. Farrell , T. Jonathan Davies , David A. Stephens

Over the past decade, random forest models have become widely used as a robust method for high-dimensional data regression tasks. In part, the popularity of these models arises from the fact that they require little hyperparameter tuning…

Machine Learning · Computer Science 2020-03-18 Shipra Malhotra , John Karanicolas

A phylogenetic tree is an important way in Bioinformatics to find the evolutionary relationship among biological species. In this research, a proposed model is described for the estimation of a phylogenetic tree for a given set of data. To…

Populations and Evolution · Quantitative Biology 2025-09-03 S M Rafiuddin

Background: Speciation corresponds to the progressive establishment of reproductive barriers between groups of individuals derived from an ancestral stock. Since Darwin did not believe that reproductive barriers could be selected for, he…

Populations and Evolution · Quantitative Biology 2011-12-12 Etienne Joly

While Deep Learning has demonstrated impressive results in applications on various data types, it continues to lag behind tree-based methods when applied to tabular data, often referred to as the last "unconquered castle" for neural…

Machine Learning · Computer Science 2026-02-27 Marius Dragoi , Florin Gogianu , Elena Burceanu

Given overlapping subsets of a set of taxa (e.g. species), and posterior distributions on phylogenetic tree topologies for each of these taxon sets, how can we infer a posterior distribution on phylogenetic tree topologies for the entire…

Populations and Evolution · Quantitative Biology 2021-04-23 Michael Karcher , Cheng Zhang , Frederick A Matsen

Probabilistic metric embedding into trees is a powerful technique for designing online algorithms. The standard approach is to embed the entire underlying metric into a tree metric and then solve the problem on the latter. The overhead in…

Data Structures and Algorithms · Computer Science 2024-09-02 Yair Bartal , Ora N. Fandina , Seeun William Umboh

Inference of the marginal likelihood of sample allele configurations using backward algorithms yields identical results with the Kingman coalescent, the Moran model, and the diffusion model (up to a scaling of time). For inference of…

Populations and Evolution · Quantitative Biology 2021-12-20 Claus Vogl , Sandra Peer , Lynette Caitlin Mikula

Rapid advancements in genome sequencing have led to the collection of vast amounts of genomics data. Researchers may be interested in using machine learning models on such data to predict the pathogenicity or clinical significance of a…

Quantitative Methods · Quantitative Biology 2024-08-15 Arshmeet Kaur , Morteza Sarmadi

In computational phylogenetics, the problem of constructing a supertree of a given set of rooted input trees can be formalized in different ways, to cope with contradictory information in the input. We consider the Minimum Flip Supertree…

Data Structures and Algorithms · Computer Science 2011-04-25 Sebastian Böcker
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