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Modern applications of survival analysis increasingly involve time-dependent covariates. The Python package BoXHED2.0 is a tree-boosted hazard estimator that is fully nonparametric, and is applicable to survival settings far more general…

Machine Learning · Computer Science 2023-09-08 Arash Pakbin , Xiaochen Wang , Bobak J. Mortazavi , Donald K. K. Lee

Given functional data from a survival process with time-dependent covariates, we derive a smooth convex representation for its nonparametric log-likelihood functional and obtain its functional gradient. From this, we devise a generic…

Machine Learning · Statistics 2021-10-07 Donald K. K. Lee , Ningyuan Chen , Hemant Ishwaran

Electronic Health Record (EHR) systems provide critical, rich and valuable information at high frequency. One of the most exciting applications of EHR data is in developing a real-time mortality warning system with tools from survival…

Machine Learning · Computer Science 2021-11-12 Zhale Nowroozilarki , Arash Pakbin , James Royalty , Donald K. K. Lee , Bobak J. Mortazavi

We propose a nonparametric method for dynamic prediction in event history analysis with high-dimensional, time-dependent covariates. The approach estimates future conditional hazards by combining landmarking supermodels with gradient…

Statistics Theory · Mathematics 2026-01-27 Oliver Lunding Sandqvist

Prognostic models in survival analysis are aimed at understanding the relationship between patients' covariates and the distribution of survival time. Traditionally, semi-parametric models, such as the Cox model, have been assumed. These…

Machine Learning · Statistics 2020-11-06 Denise Rava , Jelena Bradic

This paper investigates the integration of gradient boosted decision trees and varying coefficient models. We introduce the tree boosted varying coefficient framework which justifies the implementation of decision tree boosting as the…

Methodology · Statistics 2019-04-03 Yichen Zhou , Giles Hooker

Electronic health records (EHR) are widely used to study clinical decisions, yet unmeasured confounding remains a persistent challenge. Proxy variables offer a potential solution. In EHR data, clinicians already record many such…

Methodology · Statistics 2026-03-23 Haley Colgate Kottler , Amy Cochran

Gradient boosted trees are competition-winning, general-purpose, non-parametric regressors, which exploit sequential model fitting and gradient descent to minimize a specific loss function. The most popular implementations are tailored to…

Machine Learning · Computer Science 2022-08-23 Lorenzo Nespoli , Vasco Medici

Bayesian additive regression trees (BART) (Chipman et. al., 2010) is a powerful predictive model that often outperforms alternative models at out-of-sample prediction. BART is especially well-suited to settings with unstructured predictor…

Machine Learning · Statistics 2019-03-15 Jingyu He , Saar Yalov , P. Richard Hahn

In epidemiological studies of time-to-event data, a quantity of interest to the clinician and the patient is the risk of an event given a covariate profile. However, methods relying on time matching or risk-set sampling (including Cox…

Methodology · Statistics 2020-09-23 Sahir Rai Bhatnagar , Maxime Turgeon , Jesse Islam , James A. Hanley , Olli Saarela

Survival analysis is a statistical framework for modeling time-to-event data. It plays a pivotal role in medicine, reliability engineering, and social science research, where understanding event dynamics even with few data samples is…

Machine Learning · Computer Science 2026-02-03 Alberto Archetti , Eugenio Lomurno , Diego Piccinotti , Matteo Matteucci

In recent years, the growing availability of biomedical datasets featuring numerous longitudinal covariates has motivated the development of several multi-step methods for the dynamic prediction of survival outcomes. These methods employ…

Methodology · Statistics 2026-01-14 Mirko Signorelli , Sophie Retif

In various data situations joint models are an efficient tool to analyze relationships between time dependent covariates and event times or to correct for event-dependent dropout occurring in regression analysis. Joint modeling connects a…

Methodology · Statistics 2018-10-25 Colin Griesbach , Andreas Mayr , Elisabeth Waldmann

We propose a novel tree-based ensemble method, named XGBoostPP, to nonparametrically estimate the intensity of a point process as a function of covariates. It extends the use of gradient-boosted regression trees (Chen & Guestrin, 2016) to…

Methodology · Statistics 2024-02-01 C. Lu , Y. Guan , M. N. M. van Lieshout , G. Xu

Linear mixed models are widely used for clustered data, but their reliance on parametric forms limits flexibility in complex and high-dimensional settings. In contrast, gradient boosting methods achieve high predictive accuracy through…

Machine Learning · Statistics 2025-11-04 Mitchell L. Prevett , Francis K. C. Hui , Zhi Yang Tho , A. H. Welsh , Anton H. Westveld

Time-varying covariates are often available in survival studies and estimation of the hazard function needs to be updated as new information becomes available. In this paper, we investigate several different easy-to-implement ways that…

Methodology · Statistics 2021-03-04 Hoora Moradian , Weichi Yao , Denis Larocque , Jeffrey S. Simonoff , Halina Frydman

Heart rate measuring based on remote photoplethysmography (rPPG) plays an important role in health caring, which estimates heart rate from facial video in a non-contact, less-constrained way. End-to-end neural network is a main branch of…

Computer Vision and Pattern Recognition · Computer Science 2022-09-28 Weiyu Sun , Xinyu Zhang , Ying Chen , Yun Ge , Chunyu Ji , Xiaolin Huang

Stress, anxiety, and nervousness are all high-risk health states in everyday life. Previously, stress levels were determined by speaking with people and gaining insight into what they had experienced recently or in the past. Typically,…

Signal Processing · Electrical Eng. & Systems 2022-04-08 Sadhana Tiwari , Sonali Agarwal

Survival analysis, or time-to-event analysis, is an important and widespread problem in healthcare research. Medical research has traditionally relied on Cox models for survival analysis, due to their simplicity and interpretability. Cox…

Machine Learning · Computer Science 2023-10-25 Mike Van Ness , Tomas Bosschieter , Natasha Din , Andrew Ambrosy , Alexander Sandhu , Madeleine Udell

In this paper, we propose a gradient boosting algorithm for large-scale regression problems called \textit{Gradient Boosted Binary Histogram Ensemble} (GBBHE) based on binary histogram partition and ensemble learning. From the theoretical…

Machine Learning · Statistics 2021-06-04 Hanyuan Hang , Tao Huang , Yuchao Cai , Hanfang Yang , Zhouchen Lin
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