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We address the problem of supporting radiologists in the longitudinal management of lung cancer. Therefore, we proposed a deep learning pipeline, composed of four stages that completely automatized from the detection of nodules to the…

Image and Video Processing · Electrical Eng. & Systems 2021-03-29 Xavier Rafael-Palou , Anton Aubanell , Mario Ceresa , Vicent Ribas , Gemma Piella , Miguel A. González Ballester

Computed tomography (CT) examinations are commonly used to predict lung nodule malignancy in patients, which are shown to improve noninvasive early diagnosis of lung cancer. It remains challenging for computational approaches to achieve…

Computer Vision and Pattern Recognition · Computer Science 2018-02-07 Jason Causey , Junyu Zhang , Shiqian Ma , Bo Jiang , Jake Qualls , David G. Politte , Fred Prior , Shuzhong Zhang , Xiuzhen Huang

The introduction of lung cancer screening programs will produce an unprecedented amount of chest CT scans in the near future, which radiologists will have to read in order to decide on a patient follow-up strategy. According to the current…

Early detection of lung cancer is crucial for effective treatment and relies on accurate volumetric assessment of pulmonary nodules in CT scans. Traditional methods, such as consolidation-to-tumor ratio (CTR) and spherical approximation,…

Image and Video Processing · Electrical Eng. & Systems 2025-08-29 Yihan Zhou , Haocheng Huang , Yue Yu , Jianhui Shang

Characterization of lung nodules as benign or malignant is one of the most important tasks in lung cancer diagnosis, staging and treatment planning. While the variation in the appearance of the nodules remains large, there is a need for a…

Computer Vision and Pattern Recognition · Computer Science 2018-10-18 Sarfaraz Hussein , Robert Gillies , Kunlin Cao , Qi Song , Ulas Bagci

Early diagnosis of lung cancer is challenging due to biological uncertainty and the limited understanding of the biological mechanisms driving nodule progression. To address this, we propose Nodule-Aligned Multimodal (Latent) Diffusion…

Computer Vision and Pattern Recognition · Computer Science 2026-03-18 James Song , Yifan Wang , Chuan Zhou , Liyue Shen

Pulmonary nodules are an early sign of lung cancer, and detecting them early is vital for improving patient survival rates. Most current methods use only single Computed Tomography (CT) images to assess nodule malignancy. However, doctors…

Image and Video Processing · Electrical Eng. & Systems 2025-01-29 Yin Shen , Zhaojie Fang , Ke Zhuang , Guanyu Zhou , Xiao Yu , Yucheng Zhao , Yuan Tian , Ruiquan Ge , Changmiao Wang , Xiaopeng Fan , Ahmed Elazab

Deep learning, as a promising new area of machine learning, has attracted a rapidly increasing attention in the field of medical imaging. Compared to the conventional machine learning methods, deep learning requires no hand-tuned feature…

Quantitative Methods · Quantitative Biology 2016-11-29 He Yang , Hengyong Yu , Ge Wang

In this paper, we propose a novel framework with 3D convolutional networks (ConvNets) for automated detection of pulmonary nodules from low-dose CT scans, which is a challenging yet crucial task for lung cancer early diagnosis and…

Computer Vision and Pattern Recognition · Computer Science 2017-08-15 Qi Dou , Hao Chen , Yueming Jin , Huangjing Lin , Jing Qin , Pheng-Ann Heng

Pulmonary pathologies are a significant global health concern, often leading to fatal outcomes if not diagnosed and treated promptly. Chest radiography serves as a primary diagnostic tool, but the availability of experienced radiologists…

Image and Video Processing · Electrical Eng. & Systems 2024-12-17 Abdelbaki Souid , Mohamed Hamroun , Soufiene Ben Othman , Hedi Sakli , Naceur Abdelkarim

The accurate classification of benign and malignant pulmonary nodules in CT scans is critical for early lung cancer screening, yet remains challenging due to the multi-scale and heterogeneous nature of pulmonary nodules. While deep learning…

Computer Vision and Pattern Recognition · Computer Science 2026-05-14 Jinyue Li , Yuzhou Yu , Jingjing Yang , Meng Fu , Yani Zhang , Shuyao He , Dianlong Ge , Xin Ning , Yannan Chu , Qiankun Li

Lung cancer has the highest mortality rate of deadly cancers in the world. Early detection is essential to treatment of lung cancer. However, detection and accurate diagnosis of pulmonary nodules depend heavily on the experiences of…

Image and Video Processing · Electrical Eng. & Systems 2022-04-12 Chenglong Wang , Yun Liu , Fen Wang , Chengxiu Zhang , Yida Wang , Mei Yuan , Guang Yang

Lung cancer follow-up is a complex, error prone, and time consuming task for clinical radiologists. Several lung CT scan images taken at different time points of a given patient need to be individually inspected, looking for possible…

Image and Video Processing · Electrical Eng. & Systems 2019-12-24 Xavier Rafael-Palou , Anton Aubanell , Ilaria Bonavita , Mario Ceresa , Gemma Piella , Vicent Ribas , Miguel Ángel González Ballester

Nodule malignancy assessment is a complex, time-consuming and error-prone task. Current clinical practice requires measuring changes in size and density of the nodule at different time-points. State of the art solutions rely on 3D…

Image and Video Processing · Electrical Eng. & Systems 2020-05-27 Xavier Rafael-Palou , Anton Aubanell , Ilaria Bonavita , Mario Ceresa , Gemma Piella , Vicent Ribas , Miguel A. González Ballester

Detecting malignant pulmonary nodules at an early stage can allow medical interventions which may increase the survival rate of lung cancer patients. Using computer vision techniques to detect nodules can improve the sensitivity and the…

Image and Video Processing · Electrical Eng. & Systems 2020-10-30 Siqi Liu , Arnaud Arindra Adiyoso Setio , Florin C. Ghesu , Eli Gibson , Sasa Grbic , Bogdan Georgescu , Dorin Comaniciu

The 3D simulation model of the lung was established by using the reconstruction method. A computer aided pulmonary nodule detection model was constructed. The process iterates over the images to refine the lung nodule recognition model…

Image and Video Processing · Electrical Eng. & Systems 2024-06-21 Yutian Yang , Hongjie Qiu , Yulu Gong , Xiaoyi Liu , Yang Lin , Muqing Li

Early detection of pulmonary cancer is the most promising way to enhance a patient's chance for survival. Accurate pulmonary nodule detection in computed tomography (CT) images is a crucial step in diagnosing pulmonary cancer. In this…

Computer Vision and Pattern Recognition · Computer Science 2017-08-30 Jia Ding , Aoxue Li , Zhiqiang Hu , Liwei Wang

Automatic diagnosing lung cancer from Computed Tomography (CT) scans involves two steps: detect all suspicious lesions (pulmonary nodules) and evaluate the whole-lung/pulmonary malignancy. Currently, there are many studies about the first…

Computer Vision and Pattern Recognition · Computer Science 2019-02-04 Fangzhou Liao , Ming Liang , Zhe Li , Xiaolin Hu , Sen Song

Lung cancer ranks as one of the leading causes of cancer diagnosis and is the foremost cause of cancer-related mortality worldwide. The early detection of lung nodules plays a pivotal role in improving outcomes for patients, as it enables…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Jiasen Zhang , Mingrui Yang , Weihong Guo , Brian A. Xavier , Michael Bolen , Xiaojuan Li

The early identification of malignant pulmonary nodules is critical for better lung cancer prognosis and less invasive chemo or radio therapies. Nodule malignancy assessment done by radiologists is extremely useful for planning a preventive…

Image and Video Processing · Electrical Eng. & Systems 2019-12-19 Ilaria Bonavita , Xavier Rafael-Palou , Mario Ceresa , Gemma Piella , Vicent Ribas , Miguel A. González Ballester
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