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Machine learning has been successfully used in critical domains, such as medicine. However, extracting meaningful insights from biomedical data is often constrained by the lack of their available disease labels. In this research, we…
Fueled by breakthrough technology developments, the biological, biomedical, and behavioral sciences are now collecting more data than ever before. There is a critical need for time- and cost-efficient strategies to analyze and interpret…
Understanding disease relationships through blood biomarkers offers a pathway toward data-driven taxonomy and precision medicine. In this study, we constructed a digital blood twin, a computational model derived from 103 disease signatures…
With the increasing complexity of industrial production systems, accurate fault diagnosis is essential to ensure safe and efficient system operation. However, due to changes in production demands, dynamic process adjustments, and complex…
Missing data is a common challenge in observational studies. Another challenge stems from the observational nature of the study itself. Here, propensity score analysis can be used as a technique to replicate conditions similar to those…
Identifying disease interconnections through manual analysis of large-scale clinical data is labor-intensive, subjective, and prone to expert disagreement. While machine learning (ML) shows promise, three critical challenges remain: (1)…
Brain disorders in the early and late life of humans potentially share pathological alterations in brain functions. However, the key evidence from neuroimaging data for pathological commonness remains unrevealed. To explore this hypothesis,…
In this paper, we explore the possibility to apply machine learning to make diagnostic predictions using discomfort drawings. A discomfort drawing is an intuitive way for patients to express discomfort and pain related symptoms. These…
Medical imaging is an important research field with many opportunities for improving patients' health. However, there are a number of challenges that are slowing down the progress of the field as a whole, such optimizing for publication. In…
Content Warning: This paper contains examples of misgendering and erasure that could be offensive and potentially triggering. Misgendering, the act of incorrectly addressing someone's gender, inflicts serious harm and is pervasive in…
miRNA mRNA relations are closely linked to several biological processes and disease mechanisms In a recent study we tested the performance of large language models LLMs on extracting miRNA mRNA relations from PubMed PubMedBERT achieved the…
In conducting preliminary analysis during an epidemic, data on reported disease cases offer key information in guiding the direction to the in-depth analysis. Models for growth and transmission dynamics are heavily dependent on preliminary…
With the advent of modern computer networks, fault diagnosis has been a focus of research activity. This paper reviews the history of fault diagnosis in networks and discusses the main methods in information gathering section, information…
Aggregated Relational Data (ARD) contain summary information about individual social networks and are widely used to estimate social network characteristics and the size of populations of interest. Although a variety of ARD estimators…
Heart disease is the leading cause of death worldwide. Currently, 33% of cases are misdiagnosed, and approximately half of myocardial infarctions occur in people who are not predicted to be at risk. The use of Artificial Intelligence could…
Model-based diagnosis reasons backwards from a functional schematic of a system to isolate faults given observations of anomalous behavior. We develop a fully probabilistic approach to model based diagnosis and extend it to support…
Insufficiently precise diagnosis of clinical disease is likely responsible for many treatment failures, even for common conditions and treatments. With a large enough dataset, it may be possible to use unsupervised machine learning to…
This paper addresses patient heterogeneity associated with prediction problems in biomedical applications. We propose a systematic hypothesis testing approach to determine the existence of patient subgroup structure and the number of…
Machine-learned diagnosis models have shown promise as medical aides but are trained under a closed-set assumption, i.e. that models will only encounter conditions on which they have been trained. However, it is practically infeasible to…
Mining relationships between treatment(s) and medical problem(s) is vital in the biomedical domain. This helps in various applications, such as decision support system, safety surveillance, and new treatment discovery. We propose a deep…