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Within diagnostic reasoning there have been a number of proposed definitions of a diagnosis, and thus of the most likely diagnosis, including most probable posterior hypothesis, most probable interpretation, most probable covering…
Diseases involve complex processes and modifications to the cellular machinery. The gene expression profile of the affected cells contains characteristic patterns linked to a disease. Hence, biological knowledge pertaining to a disease can…
MicroRNAs play critical roles in many physiological processes. Their dysregulations are also closely related to the development and progression of various human diseases, including cancer. Therefore, identifying new microRNAs that are…
Large language models (LLMs) are becoming increasingly relevant as a potential tool for healthcare, aiding communication between clinicians, researchers, and patients. However, traditional evaluations of LLMs on medical exam questions do…
The healthcare sector is an important pillar of every community, numerous research studies have been carried out in this context to optimize medical processes and improve care quality and facilitate patient management. In this article we…
Large language models (LLMs) have broad medical knowledge and can reason about medical information across many domains, holding promising potential for diverse medical applications in the near future. In this study, we demonstrate a…
The rapid dissemination of health misinformation poses an increasing risk to public health. To best understand the way of combating health misinformation, it is important to acknowledge how the fundamental characteristics of misinformation…
We consider a patient risk models which has access to patient features such as vital signs, lab values, and prior history but does not have access to a patient's diagnosis. For example, this occurs in a model deployed at intake time for…
There have been reports of correlation between estimates of prevalence and test accuracy across studies included in diagnostic meta-analyses. It has been hypothesized that this unexpected association arises because of certain biases…
The relation classification task assigns the proper semantic relation to a pair of subject and object entities; the task plays a crucial role in various text mining applications, such as knowledge graph construction and entities interaction…
Biomedical research has revealed the crucial role of miRNAs in the progression of many diseases, and computational prediction methods are increasingly proposed for assisting biological experiments to verify miRNA-disease associations…
Diagnostic reasoning has been characterized logically as consistency-based reasoning or abductive reasoning. Previous analyses in the literature have shown, on the one hand, that choosing the (in general more restrictive) abductive…
Electronic Health Records maintained in health care settings are a potential source of substantial clinical knowledge. The massive volume of data, unstructured nature of records and obligatory requirement of domain acquaintance together…
Computer-aided diagnosis (CAD), a vibrant medical imaging research field, is expanding quickly. Because errors in medical diagnostic systems might lead to seriously misleading medical treatments, major efforts have been made in recent years…
In the context of personalized medicine, text mining methods pose an interesting option for identifying disease-gene associations, as they can be used to generate novel links between diseases and genes which may complement knowledge from…
Social media contains unfiltered and unique information, which is potentially of great value, but, in the case of misinformation, can also do great harm. With regards to biomedical topics, false information can be particularly dangerous.…
A patient is often willing to quickly get, from his physician, reliable analysis and concise explanation according to provided linked medical images. The fact of making choices individually by the patient's physician may lead to…
Machine Learning (ML) has garnered considerable attention from researchers and practitioners as a new and adaptable tool for disease diagnosis. With the advancement of ML and the proliferation of papers and research in this field, a…
This paper describes a novel approach to medical diagnosis based on the SP theory of computing and cognition. The main attractions of this approach are: a format for representing diseases that is simple and intuitive; an ability to cope…
Automated learning of patients demographics can be seen as multi-label problem where a patient model is based on different race and gender groups. The resulting model can be further integrated into Privacy-Preserving Data Mining, where it…