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This paper proposes a data-driven approximate Bayesian computation framework for parameter estimation and uncertainty quantification of epidemic models, which incorporates two novelties: (i) the identification of the initial conditions by…

Applications · Statistics 2023-06-28 Americo Cunha , David A. W. Barton , Thiago G. Ritto

We consider the problem of inference for the states and parameters of a continuous-time multitype branching process from partially observed time series data. Exact inference for this class of models, typically using sequential Monte Carlo,…

Methodology · Statistics 2025-12-01 Angus Lewis , Antonio Parrella , John Maclean , Andrew J. Black

We develop a stochastic two-patch epidemic model with nonlinear recidivism to investigate infectious disease dynamics in heterogeneous populations. Extending a deterministic framework, we introduce stochasticity to account for random…

Populations and Evolution · Quantitative Biology 2024-05-21 Juan G. Calvo , Mario I. Simoy , Juan P. Aparicio , José E. Chacón , Fabio Sanchez

Sequential Monte Carlo methods are a powerful framework for approximating the posterior distribution of a state variable in a sequential manner. They provide an attractive way of analyzing dynamic systems in real-time, taking into account…

Populations and Evolution · Quantitative Biology 2024-08-29 Dhorasso Temfack , Jason Wyse

Monte Carlo methods to evaluate and maximize the likelihood function enable the construction of confidence intervals and hypothesis tests, facilitating scientific investigation using models for which the likelihood function is intractable.…

Methodology · Statistics 2017-02-13 Edward L. Ionides , Carles Breto , Joonha Park , Richard A. Smith , Aaron A. King

Stochastic epidemic models describe the dynamics of an epidemic as a disease spreads through a population. Typically, only a fraction of cases are observed at a set of discrete times. The absence of complete information about the time…

Computation · Statistics 2017-02-14 Jonathan Fintzi , Xiang Cui , Jon Wakefield , Vladimir N. Minin

Traditional compartmental models capture population-level dynamics but fail to characterize individual-level risk. The computational cost of exact likelihood evaluation for partially observed individual-based models, however, grows…

Methodology · Statistics 2026-01-27 Lorenzo Rimella , Nick Whiteley , Chris Jewell , Paul Fearnhead , Michael Whitehouse

The estimation of unknown parameters in simulations, also known as calibration, is crucial for practical management of epidemics and prediction of pandemic risk. A simple yet widely used approach is to estimate the parameters by minimizing…

Methodology · Statistics 2023-06-26 Chih-Li Sung , Ying Hung

Stochastic epidemic models which incorporate interactions between space and human mobility are a key tool to inform prioritisation of outbreak control to appropriate locations. However, methods for fitting such models to national-level…

The transmission dynamics of an epidemic are rarely homogeneous. Super-spreading events and super-spreading individuals are two types of heterogeneous transmissibility. Inference of super-spreading is commonly carried out on secondary case…

Quantitative Methods · Quantitative Biology 2025-01-23 Hannah Craddock , Simon EF Spencer , Xavier Didelot

This article investigates stochastic epidemic models with partial information and addresses the estimation of current values of not directly observable states. The latter is also called nowcasting and related to the so-called "dark figure"…

Populations and Evolution · Quantitative Biology 2025-06-03 Florent Ouabo Kamkumo , Ibrahim Mbouandi Njiasse , Ralf Wunderlich

In this paper we introduce a novel method to conduct inference with models defined through a continuous-time Markov process, and we apply these results to a classical stochastic SIR model as a case study. Using the inverse-size expansion of…

Applications · Statistics 2011-11-10 Marcos A. Capistrán , J. Andrés Christen , Jorge X. Velasco-Hernández

The COVID-19 pandemic has been characterised by multiple waves of transmission driven by interventions and emerging variants, challenging epidemic models that assume gradually evolving transmission dynamics. We propose a class of…

Applications · Statistics 2026-05-05 Patrick Aschermayr , Konstantinos Kalogeropoulos , Nikolaos Demiris

We consider a time-inhomogeneous diffusion process able to describe the dynamics of infected people in a susceptible-infectious epidemic model in which the transmission intensity function is time-dependent. Such a model is well suited to…

Methodology · Statistics 2024-10-30 Giuseppina Albano , Virginia Giorno , Francisco Torres-Ruiz

We use a multivariate formulation of sequential Monte Carlo filter that utilizes mechanistic models for Ebola virus propagation and available incidence data to simultaneously estimate the disease progression states and the model parameters.…

We propose a generative model and an inference scheme for epidemic processes on dynamic, adaptive contact networks. Network evolution is formulated as a link-Markovian process, which is then coupled to an individual-level stochastic SIR…

Methodology · Statistics 2020-04-07 Fan Bu , Allison E. Aiello , Jason Xu , Alexander Volfovsky

Despite the recent development of methods dealing with partially observed epidemic dynamics (unobserved model coordinates, discrete and noisy outbreak data), limitations remain in practice, mainly related to the quantity of augmented data…

Applications · Statistics 2021-07-26 Romain Narci , Maud Delattre , Catherine Larédo , Elisabeta Vergu

Two stochastic models are proposed to describe the evolution of the COVID-19 pandemic. In the first model the population is partitioned into four compartments: susceptible $S$, infected $I$, removed $R$ and dead people $D$. In order to have…

Populations and Evolution · Quantitative Biology 2021-09-16 Fabiana Calleri , Giovanni Nastasi , Vittorio Romano

Statistical inference with non-probability survey samples is an emerging topic in survey sampling and official statistics and has gained increased attention from researchers and practitioners in the field. Much of the existing literature,…

Methodology · Statistics 2024-10-07 Yang Liu , Meng Yuan , Pengfei Li , Changbao Wu

This document is the Part IV of the book 'Stochastic Epidemic Models with Inference' edited by Tom Britton and Etienne Pardoux. It is written by Catherine Lar\'edo, with the contribution of Viet Chi Tran for the Chapter 4. Epidemic data…

Probability · Mathematics 2020-04-17 Catherine Larédo , Viet Chi Tran